CN107259578A - A kind of probiotic composition and preparation method thereof - Google Patents
A kind of probiotic composition and preparation method thereof Download PDFInfo
- Publication number
- CN107259578A CN107259578A CN201710671608.0A CN201710671608A CN107259578A CN 107259578 A CN107259578 A CN 107259578A CN 201710671608 A CN201710671608 A CN 201710671608A CN 107259578 A CN107259578 A CN 107259578A
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- lactobacillus
- powder
- probiotic composition
- preparation
- fermentation
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-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/147—Helveticus
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/165—Paracasei
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
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Abstract
The invention provides a kind of probiotic composition and preparation method thereof, including a variety of probiotics such as Lactobacillus plantarum, Bifidobacterium Bifidum, lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus helveticus, lactobacillus bulgaricus, lactobacillus paracasei, the ability of free radical is quickly removed with three high drop, liver protection courage, defaecation, improvement intestinal environment, quickening enteron aisle toxin expelling, improvement sleep, enhancing body, gout is alleviated in prevention, prevent cancer cell generation, moreover it is possible to be human body microelement-supplementing the characteristics of.
Description
Technical field
The present invention relates to a kind of probiotic composition and preparation method thereof.
Background technology
Probiotics refers to improve host's microecological balance and play beneficial effect, improves host health level and health status
Active bacteria formulation and its metabolite；Probiotics is present in bacterium or fungi beneficial in each tellurian corner, animal body
Mainly have：Lactic acid bacteria, Bifidobacterium, actinomyces, saccharomycete etc..The function studied in the world most powerful product is mainly at present
More than all kinds of microorganism groups into composite reactive probiotics；A kind of bacterium to animal health of prebiotic fungus strain, they can directly make
Taken for food additives, to maintain the balance of Intestinal flora.Hundreds of probiotics health product has been developed abroad,
Including：Yoghurt, yogurt, Fermented Soybean Milk containing probiotics and oral liquid, tablet, capsule, the powder containing a variety of probiotics
Last agent etc..
Existing probiotic composition is made up of Bifidobacterium and lactic acid bacteria etc. mostly, more with Yoghourt and related dairy products etc.
Form commercially occurs, and these product strains are single, function is single, effect is general, and the survival rate of bacterium is low, carry and drink
Inconvenience, does not bring the effect of probiotics into play.
The content of the invention
Present invention aims at providing a kind of probiotic composition and preparation method thereof, with solve prior art strain it is single,
Function is single, effect is general, and the survival rate of bacterium is low, carries and drink inconvenient problem.
To achieve the above object, the invention provides a kind of probiotic composition, including following content of component：Plant breast bar
Bacterium 12%, Bifidobacterium Bifidum 8%, lactobacillus acidophilus 10%, Lactobacillus rhamnosus 8%, Lactobacillus helveticus 7%, bulgarian milk bar
Bacterium 6%, lactobacillus paracasei 6%, fruits and vegetables yeast powder 43%, the fruits and vegetables yeast powder includes digestible protein enzyme, amylase, fat
Enzyme, bromelain, papain.
The present invention also provides a kind of preparation method of probiotic composition, comprises the following steps：
Step 1: Lactobacillus plantarum, Bifidobacterium Bifidum, lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus helveticus, guarantor are added
Leah lactobacillus, lactobacillus paracasei and saccharomyces cerevisiae, ferment through individual plant and are mixed, and obtain zymocyte liquid, fermentation training
The control of base initial ph value is supported in 4-8, cultivation temperature control at 30 DEG C to 50 DEG C, incubation time using fermentation termination pH value to 3-6 as
It is accurate；
Step 2: after each strain fermentation terminates, taking whole zymotic fluids to be centrifuged, concentrated, the bacterium obtained after concentration is taken
Mud, adds protective agent by the 5%-15% of bacterium mud mass ratio, is freeze-dried or is spray-dried after emulsification is uniform, made highly concentrated
Spend active microbe powder or probiotics powder；
Step 4: Lactobacillus plantarum, Bifidobacterium Bifidum, lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus helveticus, guarantor are added
Leah lactobacillus, lactobacillus paracasei mixing, viable count are controlled 106-109CFU/ grams, be prepared into complex solid powder；
Step 5: preparing fruits and vegetables zymotic fluid, detailed process is by ginger, burdock, plum, Hericium erinaceus, carrot, apple, willow
Orange, grape fruit, pears, Kiwi berry, peach, banana, mango, celery, asparagus, corn, tomato, respectively be beaten after be mixed to get it is mixed
Close slurry；
Step 6: adding 50-100 parts of white sugar and 5-10 parts of starch to every 500 parts of mixed slurries, sterilize 15min in 100 DEG C
30 DEG C are cooled to, 10-30 portions of zymotic fluids are added, the zymotic fluid includes saccharomycete, lactic acid bacteria, lactobacillus bulgaricus；Again
In 30 DEG C of -35 DEG C of progress aerobic fermentations, fermentation system pH value reaches that 4.0-4.5 terminates fermentation, obtains enzyme liquid；
Step 7: enzyme liquid is carried out to be spray-dried to obtain pectase powder, synthesis is sequentially added to pectase powder
Digestive ferment, alpha-amylase, lipase, bromelain, papain, oligomeric maltose obtain final ferment powder；
Step 8: the final ferment powder that step 7 is obtained is mixed with the complex solid powder in step 4.
Preferably, protective agent is powdered glucose, cane sugar powder, whey powder, lactose powder, serum powder, marine alga in the step 2
Any one in sugar, sodium glutamate, glycerol yeast powder, maltodextrin or any several mixing.
Preferably, each fruits and vegetables quality is divided into the step 5：2 parts of ginger, remaining is burdock, plum, Hericium erinaceus, Hu Luo
Fore-telling, apple, orange, grape fruit, pears, Kiwi berry, peach, banana, mango, celery, asparagus, corn, each 1 part of tomato.
Preferably, the step 8 is performed by GMP working specifications, and operating environment humidity is less than 30%, and temperature, which is less than, to be taken the photograph
25 DEG C of family name.
The invention has the advantages that：The probiotic composition of the present invention has three high drop, liver protection courage, defaecation, improvement
Intestinal environment, quickening enteron aisle toxin expelling, improvement sleep, strengthen the ability that body quickly removes free radical, moreover it is possible to micro- for human body supplement
Secondary element；In addition also there is ferment a little：1) balance adjustment internal system, improves Menopause and irregular menstruation
Etc. various malaise symptoms；2) balance digestive system is colonized in enteron aisle after entering human body by the characteristic of probiotics；3) people is entered
Systemic circulatory system can be that the enzyme in ferment, peptide are added human body by carrier by probiotics.Summation supplement is various beneficial to people
Trace element such as, potassium, calcium, magnesium, sodium, iron, zinc, iodine etc., the another present invention can by produced in various fruits and vegetables uniqueness biology
Alkalize enzyme, can suppress the generation of uric acid, so as to reach the function of alleviating with gout prevention.
Bifidobacterium：Treatment chronic diarrhea improves intestinal environment and can treated uses antibiotic, the newborn bar of secondary cheese because a large amount of
Bacterium can promote the balance of body microorganism species and enzyme, and stimulate specific immunologic mechanism to play prevention disease, promote
Enter development to build up health, anti-aging and prolong long-life effect, lactobacillus acidophilus：Suppress the increment pair of enteron aisle undesirable microorganism
Pathogenic microorganisms has antagonism.Lactobacillus rhamnosus：Balance improves function of intestinal canal, strengthens human autoimmune's ability, promotees
Enter the growth of Bifidobacterium and lactobacillus acidophilus, prevention help treats diarrhoea, preventing respiratory tract infection, excludes toxin, pre- preventing decayed tooth
It is tooth, pre- hypo-allergenic.
Lactobacillus helveticus：It is capable of a variety of biologically active peptides beneficial to human body of lactoalbumin hydrolysate generation, draws with suppression
Play the angiotoninase of hypertension, active effect blood pressure reduction effect, play the role of to improve sleep and increase blood calcium concentration.Plant
Thing lactobacillus：There is certain immunoregulation effect, there is inhibitory action, reduction serum cholesterol content and prevention heart and brain to pathogenic bacteria
Blood vessel, which is cured the disease, maintains intestinal flora balance to promote absorption of nutrient ingredients, alleviates lactose intolerance, suppresses the formation of tumour cell.
Lactobacillus bulgaricus：Adjust gut flora balance, improve constipation, reduction cholesterol, improve liver function, control vivotoxin,
Suppress the growth of spoilage organisms in enteron aisle, manufacture nutriment, the development of stimulation healthy cell.
In addition to objects, features and advantages described above, the present invention also has other objects, features and advantages.
The present invention is further detailed explanation below.
Embodiment
Embodiments of the invention are described in detail below, but the present invention can be limited and covered according to claim
Multitude of different ways implement.
A kind of probiotic composition, including following content of component：Lactobacillus plantarum 12%, Bifidobacterium Bifidum 8%, acidophilus breast bar
Bacterium 10%, Lactobacillus rhamnosus 8%, Lactobacillus helveticus 7%, lactobacillus bulgaricus 6%, lactobacillus paracasei 6%, fruits and vegetables hair
Ferment powder 43%, the fruits and vegetables yeast powder includes digestible protein enzyme, amylase, lipase, bromelain, papain.
A kind of preparation method of probiotic composition, comprises the following steps：
Step 1: Lactobacillus plantarum, Bifidobacterium Bifidum, lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus helveticus, guarantor are added
Leah lactobacillus, lactobacillus paracasei and saccharomyces cerevisiae, ferment through individual plant and are mixed, and obtain zymocyte liquid, fermentation training
The control of base initial ph value is supported in 4-8, cultivation temperature control at 30 DEG C to 50 DEG C, incubation time using fermentation termination pH value to 3-6 as
It is accurate；
Step 2: after each strain fermentation terminates, taking whole zymotic fluids to be centrifuged, concentrated, the bacterium obtained after concentration is taken
Mud, adds protective agent by the 5%-15% of bacterium mud mass ratio, is freeze-dried or is spray-dried after emulsification is uniform, made highly concentrated
Spend active microbe powder or probiotics powder；
Step 4: Lactobacillus plantarum, Bifidobacterium Bifidum, lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus helveticus, guarantor are added
Leah lactobacillus, lactobacillus paracasei mixing, viable count are controlled 106-109CFU/ grams, be prepared into complex solid powder；
Step 5: preparing fruits and vegetables zymotic fluid, detailed process is by ginger, burdock, plum, Hericium erinaceus, carrot, apple, willow
Orange, grape fruit, pears, Kiwi berry, peach, banana, mango, celery, asparagus, corn, tomato, respectively be beaten after be mixed to get it is mixed
Close slurry；
Step 6: adding 50-100 parts of white sugar and 5-10 parts of starch to every 500 parts of mixed slurries, sterilize 15min in 100 DEG C
30 DEG C are cooled to, 10-30 portions of zymotic fluids are added, the zymotic fluid includes saccharomycete, lactic acid bacteria, lactobacillus bulgaricus；Again
Aerobic fermentation is carried out in 30 DEG C -35 DEG C of environment, fermentation system pH value reaches that 4.0-4.5 terminates fermentation, obtains enzyme liquid；
Step 7: enzyme liquid is carried out to be spray-dried to obtain pectase powder, synthesis is sequentially added to pectase powder
Digestive ferment, alpha-amylase, lipase, bromelain, papain, oligomeric maltose obtain final ferment powder；
Step 8: the final ferment powder that step 7 is obtained is mixed with the complex solid powder in step 4.
Protective agent is powdered glucose, cane sugar powder, whey powder, lactose powder, serum powder, trehalose, paddy ammonia in the step 2
Any one in sour sodium, glycerol yeast powder, maltodextrin or any several mixing.
Each fruits and vegetables quality is divided into the step 5：2 parts of ginger, remaining be burdock, plum, Hericium erinaceus, carrot, apple,
Each 1 part of orange, grape fruit, pears, Kiwi berry, peach, banana, mango, celery, asparagus, corn, tomato.
In step 7, before enzyme liquid is spray-dried, disinfecting action can be increased, using bus bactericidal assay,
Purpose is in advance to kill harmful bacteria, more ensures health, and the process of spray drying can equally reach sterilization purpose.
The step 8 is performed by GMP working specifications, and operating environment humidity is less than 30%, and temperature is less than 25 DEG C Celsius；
In final resulting product, including 57% complex solid probiotic powder and 43% ferment powder, more specific content of component is：Plant
Lactobacillus 12%, Bifidobacterium Bifidum 8%, lactobacillus acidophilus 10%, Lactobacillus rhamnosus 8%, Lactobacillus helveticus 7%, Bulgaria
Lactobacillus 6%, lactobacillus paracasei 6%, fruits and vegetables yeast powder 43%.
The probiotic composition of the present invention has three high drop, liver protection courage, defaecation, improves intestinal environment, accelerate enteron aisle toxin expelling, change
The ability of free radical is quickly removed in kind sleep, enhancing body, moreover it is possible to be human body microelement-supplementing；In addition also there is ferment
A little：1) balance adjustment internal system, improves the various malaise symptoms such as Menopause and irregular menstruation；2) by prebiotic
The characteristic of bacterium colonizes balance digestive system after entering human body in enteron aisle；3) can be by probiotics into human recycle system
Enzyme in ferment, peptide are added human body by carrier.Various beneficial to the people trace elements of summation supplement such as, potassium, calcium, magnesium, sodium,
Iron, zinc, iodine etc., the another present invention can suppress the generation of uric acid by producing unique biological alkalization enzyme in various fruits and vegetables, from
And reach the function of alleviating with gout prevention.
Bifidobacterium：Treatment chronic diarrhea improves intestinal environment and can treated because largely using antibiotic；
Lactobacillus paracasei can promote the balance of body microorganism species and enzyme, and stimulate specific immunologic mechanism can
To play prevention disease, promote development to build up health, anti-aging and prolong long-life effect；
Lactobacillus acidophilus：Suppress the increment of enteron aisle undesirable microorganism has antagonism to pathogenic microorganisms；
Lactobacillus rhamnosus：Balance improves function of intestinal canal, strengthens human autoimmune's ability, promotes Bifidobacterium and acidophilus
The growth of lactobacillus, prevention help treats diarrhoea, preventing respiratory tract infection, exclusion toxin, pre- anti-caries, pre- hypo-allergenic.
Lactobacillus helveticus：It is capable of a variety of biologically active peptides beneficial to human body of lactoalbumin hydrolysate generation, draws with suppression
Play the angiotoninase of hypertension, active effect blood pressure reduction effect, play the role of to improve sleep and increase blood calcium concentration；
Lactobacillus plantarum：There is certain immunoregulation effect, there is inhibitory action to pathogenic bacteria, reduce serum cholesterol content
Being cured the disease with prevention cardiovascular and cerebrovascular maintains intestinal flora balance to promote absorption of nutrient ingredients, alleviates lactose intolerance, suppresses tumour
The formation of cell；
Lactobacillus bulgaricus：Gut flora balance is adjusted, improves constipation, reduction cholesterol, improves liver function, control volume
Endotoxin, the growth for suppressing spoilage organisms in enteron aisle, manufacture nutriment, the development of stimulation healthy cell.
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, for the skill of this area
For art personnel, the present invention can have various modifications and variations.Within the spirit and principles of the invention, that is made any repaiies
Change, equivalent substitution, improvement etc., should be included in the scope of the protection.
Claims (5)
1. a kind of probiotic composition, it is characterised in that including following content of component：Lactobacillus plantarum 12%, Bifidobacterium Bifidum
8%, lactobacillus acidophilus 10%, Lactobacillus rhamnosus 8%, Lactobacillus helveticus 7%, lactobacillus bulgaricus 6%, the newborn bar of secondary cheese
Bacterium 6%, fruits and vegetables yeast powder 43%, the fruits and vegetables yeast powder includes digestible protein enzyme, amylase, lipase, bromelain, wood
Melon protease.
2. the preparation method of probiotic composition as claimed in claim 1, it is characterised in that comprise the following steps：
Step 1: by Lactobacillus plantarum, Bifidobacterium Bifidum, lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus helveticus, Bulgaria
Lactobacillus, lactobacillus paracasei and saccharomyces cerevisiae, ferment through individual plant and are mixed, and obtain zymocyte liquid, fermentation culture medium
Initial ph value control is controlled at 30 DEG C to 50 DEG C in 4-8, cultivation temperature, and incubation time is defined by fermentation termination pH value to 3-6；
Step 2: after each strain fermentation terminates, taking whole zymotic fluids to be centrifuged, concentrated, the bacterium mud obtained after concentration is taken, is pressed
The 5%-15% of bacterium mud mass ratio adds protective agent, is freeze-dried or is spray-dried after emulsification is uniform, makes high concentration work
Property bacterium powder or probiotics powder；
Step 4: by Lactobacillus plantarum, Bifidobacterium Bifidum, lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus helveticus, Bulgaria
Lactobacillus, lactobacillus paracasei mixing, viable count are controlled 106-109CFU/ grams, be prepared into complex solid powder；
Step 5: prepare fruits and vegetables zymotic fluid, detailed process be by ginger, burdock, plum, Hericium erinaceus, carrot, apple, orange,
Grape fruit, pears, Kiwi berry, peach, banana, mango, celery, asparagus, corn, tomato, respectively be beaten after be mixed to get mixing
Slurry；
Step 6: adding 50-100 parts of white sugar and 5-10 parts of starch to every 500 parts of mixed slurries, the 15min that sterilized in 100 DEG C is cold again
But to 30 DEG C, 10-30 portions of zymotic fluids are added, the zymotic fluid includes saccharomycete, lactic acid bacteria, lactobacillus bulgaricus；Then at 30
DEG C of -35 DEG C progress aerobic fermentations, fermentation system pH value reaches that 4.0-4.5 terminates fermentation, obtains enzyme liquid；
Step 7: enzyme liquid is carried out to be spray-dried to obtain pectase powder, comprehensive digestion is sequentially added to pectase powder
Enzyme, alpha-amylase, lipase, bromelain, papain, oligomeric maltose obtain final ferment powder；
Step 8: the final ferment powder that step 7 is obtained is mixed with the complex solid powder in step 4.
3. the preparation method of probiotic composition according to claim 2, it is characterised in that protective agent is in the step 2
Appoint in powdered glucose, cane sugar powder, whey powder, lactose powder, serum powder, trehalose, sodium glutamate, glycerol yeast powder, maltodextrin
Meaning is a kind of or any several mixing.
4. the preparation method of probiotic composition according to claim 2, it is characterised in that each fruits and vegetables matter in the step 5
Amount is divided into：2 parts of ginger, remaining be burdock, plum, Hericium erinaceus, carrot, apple, orange, grape fruit, pears, Kiwi berry, peach,
Each 1 part of banana, mango, celery, asparagus, corn, tomato.
5. the preparation method of probiotic composition according to claim 2, it is characterised in that the step 8 is operated by GMP
Regulation enforcement, and operating environment humidity is less than 30%, temperature is less than 25 DEG C Celsius.
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107812018A (en) * | 2017-11-13 | 2018-03-20 | 浙江禾健生营养食品有限公司 | A kind of inactivated probiotic product, preparation method and applications |
| CN108159291A (en) * | 2017-12-07 | 2018-06-15 | 韩大春 | Plant extracts and probiotics compounding product and preparation method thereof |
| CN108634140A (en) * | 2018-03-08 | 2018-10-12 | 南昌大学 | A kind of high VCCompound fruit and vegetable solid beverage of content and preparation method thereof |
| CN108823125A (en) * | 2018-06-13 | 2018-11-16 | 山东巴元生物科技有限公司 | A kind of production method and application for treating sleep disturbance probiotics preparation |
| CN108850746A (en) * | 2018-07-20 | 2018-11-23 | 北京益鸿元生物科技有限公司 | A kind of strain composite beverage and preparation method thereof |
| CN109125361A (en) * | 2018-09-26 | 2019-01-04 | 广州市健全家源信息科技有限公司 | A kind of compound reducing the gentle solution acute gout arthritis symptom of high lithemia |
| CN110106122A (en) * | 2019-05-30 | 2019-08-09 | 江南大学 | It is a kind of to improve lactobacillus plantarum of sleep and application thereof |
| CN110140968A (en) * | 2019-06-18 | 2019-08-20 | 广州康泽医疗科技有限公司 | A kind of alleviation anxiety, depression adjust mood deviation, the probiotic composition for depressurizing sleeping and its preparation method and application |
| CN110301644A (en) * | 2018-03-27 | 2019-10-08 | 广州若尧特医食品科技有限公司 | Lactulose composite probiotic powder |
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| CN112273657A (en) * | 2019-07-22 | 2021-01-29 | 安琪酵母股份有限公司 | Probiotic composition for preventing or improving allergic diseases, preparation method and application |
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| CN113615838A (en) * | 2020-05-06 | 2021-11-09 | 宏浚实业有限公司 | Probiotic complexes for improving gastrointestinal health |
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| CN107812018A (en) * | 2017-11-13 | 2018-03-20 | 浙江禾健生营养食品有限公司 | A kind of inactivated probiotic product, preparation method and applications |
| CN108159291A (en) * | 2017-12-07 | 2018-06-15 | 韩大春 | Plant extracts and probiotics compounding product and preparation method thereof |
| CN108634140A (en) * | 2018-03-08 | 2018-10-12 | 南昌大学 | A kind of high VCCompound fruit and vegetable solid beverage of content and preparation method thereof |
| CN110301644A (en) * | 2018-03-27 | 2019-10-08 | 广州若尧特医食品科技有限公司 | Lactulose composite probiotic powder |
| CN108823125A (en) * | 2018-06-13 | 2018-11-16 | 山东巴元生物科技有限公司 | A kind of production method and application for treating sleep disturbance probiotics preparation |
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| CN110106122A (en) * | 2019-05-30 | 2019-08-09 | 江南大学 | It is a kind of to improve lactobacillus plantarum of sleep and application thereof |
| CN110106122B (en) * | 2019-05-30 | 2020-08-04 | 江南大学 | Lactobacillus plantarum capable of improving sleep and application thereof |
| CN110140968A (en) * | 2019-06-18 | 2019-08-20 | 广州康泽医疗科技有限公司 | A kind of alleviation anxiety, depression adjust mood deviation, the probiotic composition for depressurizing sleeping and its preparation method and application |
| CN112273657A (en) * | 2019-07-22 | 2021-01-29 | 安琪酵母股份有限公司 | Probiotic composition for preventing or improving allergic diseases, preparation method and application |
| CN111084386A (en) * | 2020-02-28 | 2020-05-01 | 大连万众益生大健康有限公司 | Probiotic supplement with function of improving intestinal tract |
| CN113615838A (en) * | 2020-05-06 | 2021-11-09 | 宏浚实业有限公司 | Probiotic complexes for improving gastrointestinal health |
| CN111838662A (en) * | 2020-07-31 | 2020-10-30 | 广西天缘绿生物科技有限公司 | High negative potential plantain fruit extract |
| CN111955742A (en) * | 2020-08-21 | 2020-11-20 | 中民集团生物科技有限公司 | Composite probiotics and preparation method thereof |
| CN113249253A (en) * | 2021-05-13 | 2021-08-13 | 内蒙古农业大学 | Production process of composite probiotics |
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