CN107115176A - A kind of vision repair system - Google Patents
A kind of vision repair system Download PDFInfo
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- CN107115176A CN107115176A CN201710361415.5A CN201710361415A CN107115176A CN 107115176 A CN107115176 A CN 107115176A CN 201710361415 A CN201710361415 A CN 201710361415A CN 107115176 A CN107115176 A CN 107115176A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1662—Instruments for inserting intraocular lenses into the eye
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- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Prostheses (AREA)
Abstract
Technical field is replaced the invention belongs to vision, it is related to the device that a kind of human eye vision is stimulated and formed, particularly a kind of vision repair system, on the basis of based on photosensitive protein, propose a kind of external power supply and collection image, display and projection arrangement are arranged in intraocular lens, and be placed in by way of implantation in human body, pass through wireless signal and electrical transfer, so that of the invention can show and be projected out in vivo in vivo the image gathered in vitro, the image that would indicate that is projected on retinal photoreceptor part through lens group, so as to stimulate optic nerve, repair vision and bring light for blindness patient.The present invention can reduce the risk of operation implantation using ripe lens insertion procedure technology simultaneously, improve security.
Description
Technical field
Technical field is replaced the invention belongs to vision, is related to the device that a kind of human eye vision is stimulated and formed, particularly
A kind of vision repair system.
Background technology
Vision is people and other most of most direct modes of biological receptive external information, and the damage of eyesight will be to life day
Often make troubles.Visual impairment can be divided into many kinds, including corneal injury, crystalline lens denaturation, retinal damage and whole eyeball
Damage or lack etc., wherein corneal graft is the effective means treated for corneal injury;And with advancing age, it is brilliant
Shape body easily occurs denaturation and causes vision disorder, and intraocular lens's transplanting is the universal means for treating lens diseases;Eyeground is regarded
Nethike embrane is part most complicated in vision system, easily occurs various lesions, when being caused retina to be damaged by wound or lesion
When will produce permanent loss vision, once retina is impaired cause blindness when, temporarily recover to regard without particularly effective treatment means
Power.
Congenital retinal degenerative disorders such as retinal pigment degeneration will cause the death of retinal photoreceptor cells, finally
Blindness will be caused, the retinitis caused by the denaturation of ganglia retinae stem cell also leads to retinal function and is damaged.For this
The problem of kind, presently, there are electrode stimulating method and ultrasound stimulation method, electrical stimulation method is to be implanted into microelectrode on the retina, body
The gangliocyte of retina is directly stimulated with coordination electrode after outer camera collection image, so as to produce visual signal, plays and regards
Feel effect, but be due to that it uses retina contact device, security is not high;Another method is exactly ultrasound stimulation
Method, stimulates retina, so that vision is produced, using non-built-in mode method so that noninvasive by launching directional ultrasound in vitro
Property is improved, but is due to the complexity of eyeball structure so that during ultrasound-transmissive, precision is greatly affected, the above two
The method of kind is all to not accurate enough in terms of cell-specific, it is impossible to be accurately positioned on specific photosensory cell.
Photaesthesia channel protein is a kind of light Pulse Width Control non-selective cation channel albumen, with the side of genetic engineering
Method, is transferred in retinal neuronal cell, can change the activity of nerve cell by illumination.
The content of the invention
For problem above, and combine the characteristic of photosensitive protein, the purpose of the present invention on the basis of based on photosensitive protein,
Propose a kind of vision repair system.
In order to solve the above technical problems, one aspect of the present invention is:A kind of vision repair system is provided, wrapped
Device outside and vivo devices are included, the device outside includes image capture module, the first wireless signal transmission module, wireless confession
Electric module;The vivo devices include second wireless singal transport module, image and show that projection module, wireless power receive mould
Block;Described image acquisition module collection image information is sent to vivo devices by the first wireless signal transmission module;Described second
Wireless signal transmission module receives image information and is shown and be projected on retina light sensation part by image display projection module, enters
And produce optic nerve reaction.
Further, described image capture module, including micro-camera and picture processing chip;The micro-camera is used
In the picture signal of collection drawing axis, described image process chip is used to the picture signal of collection is optimized and changed,
And according to image effect, control micro-camera is focused.
Further, described image shows that projection module includes crystalline lens and shrinks induction installation, and the crystalline lens shrinks
Induction installation includes pressure sensitive circle and pressure signal process chip, and pressure sensitive circle is made up of a kind of flexible material, passes through root
Pressure and deformation according to itself each point, measure contraction control data of the ciliary muscle to vivo devices, and will shrink control data warp
First wireless signal transmission module is sent to image capture module, and described image acquisition module is micro- according to control data control is shunk
Type camera is focused.
As an improvement, described image shows that projection module also includes image display panel and projection lens set;Described
Projection lens set includes simple lens or lens array.
As a further improvement, the device outside also include power supply, the power supply respectively with image capture module and nothing
Line power supply module is connected;The power supply is that image shows that projection module is supplied by wireless power supply module and wireless power receiving module
Electricity.
Specifically, described image shows the image display panel in projection module, the image information for showing collection is described
Projection lens set is used for the image projection of display to eye ground, to form vision.
As an improvement, described image shows the image display panel in projection module, is the one of plane screen or Curved screen
Kind, shape can be square, circular or polygon.
Specifically, described image shows that the focal plane of projection module is located on retina light sensation part.
Specifically, the device outside is arranged on eye frame or used wear-type structure.
A kind of vision repair system of the present invention, on the basis of based on photosensitive protein, proposes a kind of external power supply and gathers
Image, display and projection arrangement are arranged in intraocular lens, and are placed in by way of implantation in human body, pass through wireless communication
Number and electrical transfer so that in vivo can the present invention can show and be projected out in vivo the image that gathers in vitro, would indicate that
Image be projected in through lens group on retinal photoreceptor part, so as to stimulate optic nerve, repair vision and brought for blindness patient
It is bright.The present invention can reduce the risk of operation implantation using ripe lens insertion procedure technology simultaneously, improve safety
Property.
Brief description of the drawings
Fig. 1 is a kind of overall schematic block diagram of vision repair system of the invention;
Fig. 2 is a kind of embodiment schematic block diagram of vision repair system of the invention;
Fig. 3 is a kind of vivo devices schematic block diagram of vision repair system of the invention.
Embodiment
A kind of vision repair system that the present invention is provided is illustrated below in conjunction with Fig. 1 to Fig. 3.
As shown in figure 1, being present invention specific implementation lens implanting formula vision repair system of the case based on photosensitive protein
Schematic block diagram;A kind of vision repair system, including device outside 1 and vivo devices 2, the device outside 1 include IMAQ
Module 11, the first wireless signal transmission module 12, wireless power supply module 13;The vivo devices 2 are passed including second wireless singal
Defeated module 21, image show projection module 22, wireless power receiving module 23;Described image acquisition module 11 gathers image information
Sent by the first wireless signal transmission module 12 to vivo devices 2;The second wireless singal transport module 21 receives image letter
Breath is shown and is projected on retina light sensation part 3 by image display projection module 22, and then produces optic nerve reaction.
The device outside is arranged on eye frame or used wear-type structure.It is arranged on device outside on glasses
Exemplified by, frame structure uses conventional glasses profile, as shown in Fig. 2 described image capture module 11, including Miniature phase
Machine 111 and picture processing chip 112;The micro-camera 111 is used for the picture signal for gathering drawing axis, described image processing
Chip 112 is used to the picture signal of collection is optimized and changed, and according to image effect, control micro-camera 111 enters
Row focusing.In order to simulate the binocular vision of human eye as far as possible, a pair of micro-cameras 111 are separately mounted on left and right picture frame 16,
And make it that the pupil location of micro-camera 111 facing away from the field-of-view image immediately ahead of the pupil position of human eye, collection, and by collection
Image transmitting is given in the image procossing integrated chip 112 that micro-camera 111 is connected, and carries out image procossing and optimization, feedback
The focal length of micro-camera 111 is adjusted, so as to strengthen the recognition effect of primary objects in collection image.Image capture module distinguishes position
It is symmetrical in left and right picture frame, micro-camera be can 2X zooms pinhole camera, 4 mega pixels, picture processing chip it is main
Employ contours extract and image multilevel threshold segmentation scheduling algorithm.
Further, described image shows that projection module includes crystalline lens and shrinks induction installation 24, and the crystalline lens shrinks
Induction installation includes pressure sensitive circle and pressure signal process chip, and pressure sensitive circle is made up of a kind of flexible material, passes through root
Pressure and deformation according to itself each point, measure contraction control data of the ciliary muscle to vivo devices, and will shrink control data warp
First wireless signal transmission module is sent to image capture module, and described image acquisition module is micro- according to control data control is shunk
Type camera is focused.As a kind of preferred embodiment, described image shows that projection module also includes image display panel and projection
Lens group;Described projection lens set includes simple lens or lens array.
Image shows projection module 22, second wireless singal transport module 21 and wireless power receiving module 23 and crystalline
Body shrinks induction installation 24 and is integrated in a special intraocular lens i.e. vivo devices, is implanted into the lens capsule of eyeball
In bag;The disassembly diagram of the lens implanting module of the embodiment of the present invention is illustrated in figure 3, according to picture signal direction, is wrapped successively
Include:Intraocular lens's support frame 41, wireless power reception device 33, projection display screen 42, projection microlens array 43 and artificial
Crystalline lens filling liquid protection cap 45.The image information of collection is wirelessly transferred to second wireless singal transport module 21,
The display image of display screen 42 is focused on the retina using microlens array 43 is projected, excitation retinal photoreceptor part
The expression of photosensitive channel protein on 3.The photosensitive channel protein of retina light sensation part is by photosensitive passage egg by genetic approach
White channelrhodopsin, ChR2 DNA import cerebral stratum of retina, and progress albumen synthesis, the egg on nerve cell
Cation passage can be opened under 470nm light stimulus in vain so that cell membrane potential changes.
As a further improvement, the device outside also include power supply 14, the power supply respectively with image capture module 11
Connected with wireless power supply module 13;The power supply is that image shows projection by wireless power supply module and wireless power receiving module
Module 21 is powered.Power supply 14 is arranged on the mirror holder of glasses, in order to use power supply and short-period used convenient for a long time, power supply 14
Use compact lithium cell batteries and add extended line charging port, compact lithium cell batteries are arranged on glass frame pin 15
It is interior.The mode of wired connection is used to provide electric current for image capture module 11, also using safe to the human body and technology maturation electricity
Magnetic pumping technology is to be implanted in lenticular module for power supply.Lens implanting formula wireless power reception device 13 and wireless power hair
Penetrate module 23 and match and use, the energy that extracorporeal power source is transmitted is transported in the wireless power reception device 23 of vivo devices,
Powered after rectification for the vivo devices 2 of lens implanting formula.Wireless power agreement is supplied using ripe electromagnetic excitation technology, power supply
Piezoelectric voltage 3.3V, each module operating voltage of lens implanting is 1.1V.
In order to avoid mutual interference, the first wireless signal transmission module 12 and lens implanting formula second wireless singal are passed
Defeated module 21 uses point-to-point Bluetooth transmission protocol, can transmit the picture signal of collection to internal from device outside
Second wireless singal transport module 21 on.
Specifically, described image shows the image display panel in projection module, the image information for showing collection is described
Projection lens set is used for the image projection of display to eye ground, to form vision.
As an improvement, described image shows the image display panel in projection module, is the one of plane screen or Curved screen
Kind, shape can be square, circular or polygon.
Specifically, described image shows that the focal plane of projection module is located on retina light sensation part.
A kind of vision repair system concrete operation step of the present invention is as follows:
Step 1, power supply is connected with wireless power transmitter module and image capture module respectively, and electric energy is provided for the two;Figure
As acquisition module is connected with the first wireless signal transmission module, the picture signal of collection is transferred to second wireless singal transmission mould
Block;Wireless power receiving module shows that projection module is connected with second wireless singal transport module and image respectively, by reception
Electric energy is supplied to the two;Second wireless singal transport module shows that projection module is connected with image, and the former believes the image of reception
Number being transferred to the latter is shown.
Step 2, using wireless power mode safe to the human body, electrical power is transferred to nothing from wireless power transport module
Line is powered receiving module;Using transmission of wireless signals mode safe to the human body, by picture signal from the first transmission of wireless signals
Module transfer is to second wireless singal transport module.
Step 3, installed in image capture module in front of the micro-camera collection visual field in vitro or surrounding environment image
Signal, after certain image procossing and optimization, is conveyed to the first wireless signal transmission module, and then into intraocular implants' body
That is vivo devices image signal transmission;
Step 4, second wireless singal transport module is received after the picture signal of the first wireless signal transmission module, conveying
Projection module is shown to image;
Step 5, image shows that projection module is received after picture signal, believes image on the display screen in projection module
Number carry out image show that the image of display is projected and forms real image by projection lens set on eye ground in projection module;
Step 6, the gray scale size of image display reflects the intensity size of projected position light intensity, triggers different luminous intensities
Opening and breaking for photosensitive channel protein, so as to cause different optic nerves to react, forms visual pattern.
The vision control system of step 7, brain, according to the image of projection on the retina, may make ciliary muscle
Contractile response, so that the image to different far and near positions is focused, the pressure sensitive circle of induction installation is shunk using crystalline lens,
Each contraction control data to contraction of the ciliary muscle to retina is collected, and body is transferred to by second wireless singal transport module
In outer wireless signal transmission module.
Step 8, external first wireless signal transmission module receive contraction control data, export in image capture module
Signal analysis is carried out, and controls the collection of micro-camera, the optimization of image capture position is realized.
Embodiments of the present invention are the foregoing is only, are not intended to limit the scope of the invention, it is every to utilize this
Equivalent structure or equivalent flow conversion that description of the invention and accompanying drawing content are made, or directly or indirectly it is used in other correlations
Technical field, is included within the scope of the present invention.
Claims (9)
1. a kind of vision repair system, including device outside and vivo devices, it is characterised in that the device outside includes image
Acquisition module, the first wireless signal transmission module, wireless power supply module;The vivo devices include second wireless singal and transmit mould
Block, image show projection module, wireless power receiving module;Described image acquisition module gathers image information by the first wireless communication
Number transport module is sent to vivo devices;The second wireless singal transport module receives image information and shows projective module by image
Block shows and is projected on retina light sensation part, and then produces optic nerve reaction.
2. vision repair system as claimed in claim 1, it is characterised in that described image capture module, including Miniature phase
Machine and picture processing chip;The micro-camera is used for the picture signal for gathering drawing axis, and described image process chip is used for
The picture signal of collection is optimized and changed, and according to image effect, control micro-camera is focused.
3. vision repair system as claimed in claim 2, it is characterised in that described image shows that projection module includes crystalline lens
Induction installation is shunk, the crystalline lens, which shrinks induction installation, includes pressure sensitive circle and pressure signal process chip, pressure sensitive
Circle is made up of a kind of flexible material, passes through the pressure according to itself each point and deformation, contraction of the measurement ciliary muscle to vivo devices
Control data, and sent control data is shunk through the first wireless signal transmission module to image capture module, described image is adopted
Collection module is focused according to control data control micro-camera is shunk.
4. the vision repair system as described in claim 1-3, it is characterised in that described image shows that projection module also includes figure
As display screen and projection lens set;Described projection lens set includes simple lens or lens array.
5. the vision repair system as described in claim 1-3, it is characterised in that the device outside also includes power supply, described
Power supply is connected with image capture module and wireless power supply module respectively;The power supply is connect by wireless power supply module and wireless power
It is that image shows that projection module is powered to receive module.
6. vision repair system as claimed in claim 4, it is characterised in that described image shows that the image in projection module shows
Display screen, the image information for showing collection, the projection lens set is used for the image projection of display to eye ground,
To form vision.
7. vision repair system as claimed in claim 6, it is characterised in that described image shows that the image in projection module shows
Display screen, is one kind of plane screen or Curved screen, and shape can be square, circular or polygon.
8. vision repair system as claimed in claim 7, it is characterised in that described image shows that the focal plane of projection module is located at
On retina light sensation part.
9. vision repair system as claimed in claim 8, it is characterised in that the device outside be arranged on eye frame or
Person uses wear-type structure.
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CN201710361415.5A CN107115176A (en) | 2017-05-22 | 2017-05-22 | A kind of vision repair system |
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CN201710361415.5A CN107115176A (en) | 2017-05-22 | 2017-05-22 | A kind of vision repair system |
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Cited By (2)
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CN111026276A (en) * | 2019-12-12 | 2020-04-17 | Oppo(重庆)智能科技有限公司 | Visual aid method and related product |
CN113730029A (en) * | 2021-03-06 | 2021-12-03 | 北京大学 | Artificial eye device with built-in eyeball |
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CN113730029B (en) * | 2021-03-06 | 2022-04-26 | 北京大学 | Artificial eye device with built-in eyeball |
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