CN106265395A - A kind of compound recipe snow chrysanthemum health-care toothpaste - Google Patents
A kind of compound recipe snow chrysanthemum health-care toothpaste Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The invention discloses a kind of compound recipe snow chrysanthemum health-care toothpaste; it is belonging to a kind of health Chinese herbal toothpaste; its Main Function is to clean tooth at toothpaste itself; while protection oral hygiene health, there is heat-clearing and toxic substances removing, inhibiting bacteria and diminishing inflammation, reducing swelling and alleviating pain, nourishing YIN to relieve dryness, promoting the production of body fluid and inducing sedation of the mind, dispel halitosis, anti-treating dental ulcer and the effect of prophylaxis of teeth disease; also have without essence, the feature of pigment; use rear breath freshening, comfortable taste, oral cavity cleaning, teeth whitening, attractive in appearance and healthy can be kept.The present invention is that the Chinese herbal medicine extract that with the addition of in preparing toothpaste cream base technique and have efficacy active component includes: coreopsis tinctoria extract, Radix Ginseng extract, Ganoderma extract, Herba Dendrobii extract, Folium Et Cacumen Murrayae extract, these five kinds of Chinese herbal medicine extracts are nursing tooth and the preferable ancillary drug of prevention oral disease, itself and toothpaste cream base reasonable compatibility are made toothpaste, it is to form according to theory of Chinese medical science compatibility, all medicines are made a concerted effort, and play its effect.This product formula is gentle, safely and effectively, when brushing teeth by the mucosal absorption in oral cavity, cleaning the teeth function and preventing and treating odontopathy function and organically combine, reaches prevention and the effect kept healthy, is one of very popular product.
Description
Technical field
One compound recipe of the present invention snow chrysanthemum health-care toothpaste, it is belonging to daily-use chemical industry oral-cavity article field, relate to a kind of health Chinese herbal toothpaste, efficacy active component Chinese herbal medicine extract is included by this toothpaste: coreopsis tinctoria extract, Radix Ginseng extract, Ganoderma extract, Herba Dendrobii extract, Folium Et Cacumen Murrayae extract, in these five kinds of Chinese herbal medicine extract first Application to the product process preparing toothpaste.This toothpaste is formed with toothpaste cream base and deionized water mixed preparing by efficacy active component Chinese herbal medicine extract, there is heat-clearing and toxic substances removing, inhibiting bacteria and diminishing inflammation, reducing swelling and alleviating pain, nourishing YIN to relieve dryness, promoting the production of body fluid and inducing sedation of the mind, dispel halitosis, anti-treating dental ulcer and the effect of prophylaxis of teeth disease, also have without essence, the feature of pigment, use rear breath freshening, comfortable taste, oral cavity cleaning, teeth whitening, attractive in appearance and healthy, the present invention can be kept to also relate to the preparation technology of compound recipe snow chrysanthemum health-care toothpaste.
Background technology
Along with the constantly progress of science and technology and improving constantly of living standards of the people, nourishing healthy and health preserving conditioning to toothpaste are had higher requirement, and many toothpaste new varieties are arisen at the historic moment.One compound recipe of the present invention snow chrysanthemum health-care toothpaste is health Chinese herbal toothpaste, include containing five kinds of Chinese herbal medicine extracts with efficacy active component: coreopsis tinctoria extract, Radix Ginseng extract, Ganoderma extract, Herba Dendrobii extract, Folium Et Cacumen Murrayae extract, these five kinds of Chinese herbal medicine extracts.Record according to traditional Chinese medical science pharmacopeia: snow chrysanthemum has heat-clearing and toxic substances removing, anti-inflammation, light speckle, dispels the effect of halitosis, treats scorching excessive thirst；Radix Ginseng has the effect of strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promoting the production of body fluid and inducing sedation of the mind；Ganoderma has the QI invigorating that nourishes blood, tranquilizing by nourishing the heart, relieving cough and asthma, the liver benefiting spleen invigorating, antioxidation, antiinflammatory, antitumor, the effect of regulation immunity；Herba Dendrobii has reinforcing stomach reg fluid, nourishing YIN and clearing away heat, nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst, hepatoprotective function of gallbladder promoting, an effect of clearind deficient heat, treatment xerostomia excessive thirst, eats retch less；Folium Et Cacumen Murrayae has pain relieving, the effect of toothache of subsiding a swelling, treat.The present invention according to theory of Chinese medical science, reasonable compatibility, all medicines make a concerted effort, magistral medicines warm in nature and, zest is little, does not hinder oral mucosa.These five kinds of Chinese herbal medicine extracts are applied in formulation of tooth-paste make toothpaste by the present invention first, its objective is to provide and a kind of there is heat-clearing and toxic substances removing, inhibiting bacteria and diminishing inflammation, reducing swelling and alleviating pain, nourishing YIN to relieve dryness, promoting the production of body fluid and inducing sedation of the mind, dispel a kind of compound recipe snow chrysanthemum health-care toothpaste of halitosis, anti-treating dental ulcer and prophylaxis of teeth disease effect, it is without essence, the natural plant health-care type Chinese herbal toothpaste of pigment, the health Chinese herbal toothpaste that Ye Shi consumer expects simultaneously.
Summary of the invention
The invention discloses a kind of compound recipe containing medicinal herb components snow chrysanthemum health-care toothpaste, being by coreopsis tinctoria extract, Radix Ginseng extract, Ganoderma extract, Herba Dendrobii extract, Folium Et Cacumen Murrayae extract, these five kinds of Chinese herbal medicine extracts add toothpaste cream base to and deionized water mixed preparing forms.This toothpaste also has heat-clearing and toxic substances removing, inhibiting bacteria and diminishing inflammation, reducing swelling and alleviating pain, nourishing YIN to relieve dryness, promoting the production of body fluid and inducing sedation of the mind while having ordinary toothpaste cleaning tooth, protection oral hygiene health, dispels halitosis, the effect of anti-treating dental ulcer; also there is protection oral mucosa, reduce oral disease, prophylaxis of teeth and the effect of oral disease; it it is a kind of health Chinese herbal toothpaste; using safety, health-care effect is notable.
One compound recipe of the present invention snow chrysanthemum health-care toothpaste, described coreopsis tinctoria extract is the xeraphium of snow chrysanthemum ethanol extraction, Radix Ginseng extract is the xeraphium of Radix Ginseng ethanol extraction, Ganoderma extract is the xeraphium of Ganoderma ethanol extraction, Herba Dendrobii extract is the xeraphium of Herba Dendrobii ethanol extraction, and Folium Et Cacumen Murrayae extract is the xeraphium of Folium Et Cacumen Murrayae ethanol extraction.
One compound recipe of the present invention snow chrysanthemum health-care toothpaste, described coreopsis tinctoria extract, Radix Ginseng extract, Ganoderma extract, Herba Dendrobii extract, Folium Et Cacumen Murrayae extract, these five kinds of Chinese herbal medicine extracts are not limited to the xeraphium as avenged chrysanthemum ethanol extraction, can also be used with supercritical extract, ultrasonic extraction thing, extracting solution, extractum extract, ground product, existing commercially available Chinese medicine extract can also be used, if be applied in toothpaste by other forms such as extracting solution or extractum, the addition in formula should be converted to the addition of extract in the formula that disclosed in this invention.
Cream base in a kind of compound recipe of present invention snow chrysanthemum health-care toothpaste includes.
Abrasivus, accounting for the percentage by weight in toothpaste cream base is 20%-50%, can be selected for calcium carbonate, calcium hydrogen phosphate, silicon dioxide, sodium aluminosilicate, aluminium hydroxide and combinations thereof.
Wetting agent, accounting for the percentage by weight in toothpaste cream base is 20% ~ 70%, can be selected for sorbitol, glycerol, propylene glycol, xylitol and combinations thereof.
Foaming agent, accounting for the percentage by weight in toothpaste cream base is 1% ~ 3%, can be selected for sodium lauryl sulfate, sodium N-lauroyl sarcosinate, sodium lauroyl glutamate, lauroyl sulfoacetic acid sodium.
Adhesive, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 2%, can be selected for sodium carboxymethyl cellulose, hydroxyethyl cellulose, xanthan gum, carrageenan, guar gum and combinations thereof.
Aromatic, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 3%, can be selected for Oleum Menthae Rotundifoliae, Oleum menthae, wintergreen oil, Oleum Caryophylli, Oleum Anisi Stellati, Oleum Cinnamomi, Cladrastis kentukea Rudd oil, orange oil and combinations thereof.
Efficacy active component Chinese herbal medicine extract includes: coreopsis tinctoria extract, and accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 30%；Radix Ginseng extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Ganoderma extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Herba Dendrobii extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Folium Et Cacumen Murrayae extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%.
Preservative, accounting for the percentage by weight in toothpaste cream base is 0.05% ~ 1.5%, can be selected for sodium benzoate, methyl hydroxybenzoate, ethyl hydroxybenzoate, butoben and combinations thereof.
Corrosion inhibiter, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 2%, can be selected for sodium silicate, calcium hydrogen phosphate, disodium hydrogen phosphate, tertiary sodium phosphate, tetrasodium pyrophosphate, potassium nitrate and their combination.
Surplus is deionized water.
Five kinds of Chinese herbal medicine extracts containing efficacy active component are added in the product process preparing toothpaste by the present invention first; it it is the reasonable compatibility of Chinese herbal medicine and toothpaste cream base; protection oral hygiene health, heat-clearing and toxic substances removing, inhibiting bacteria and diminishing inflammation, reducing swelling and alleviating pain, nourishing YIN to relieve dryness, promoting the production of body fluid and inducing sedation of the mind can be played, dispel halitosis, the effect of anti-treating dental ulcer, moreover it is possible to play the effect of prophylaxis of teeth and oral condition.
One compound recipe of the present invention snow chrysanthemum health-care toothpaste is to form according to theory of Chinese medical science reasonable compatibility, all medicines are made a concerted effort, play its effect, there is oral cavity cleaning, breath freshening, comfortable taste, holding teeth whitening, attractive in appearance and healthy effect after use, have without essence, the feature of pigment, be a kind of natural plant health-care type Chinese herbal toothpaste.
Detailed description of the invention.
Being described in further detail the present invention below by specific embodiment, following example are illustrative, are not determinate, it is impossible to limit protection scope of the present invention with this.
One compound recipe of the present invention snow chrysanthemum health-care toothpaste, preparation process is by the coreopsis tinctoria extract measured, Radix Ginseng extract, Ganoderma extract, Herba Dendrobii extract, Folium Et Cacumen Murrayae extract, after these five kinds of Chinese herbal medicine extract xeraphiums and the toothpaste cream base measured and balance deionized water mixing and stirring through vacuum outgas, after the assay was approved, fill, sealing are made.
In 15 examples, toothpaste constitutive material is weight percent content below.
Example 1:
Compound recipe snow chrysanthemum health-care toothpaste is by calcium carbonate 40, glycerol 18, sodium lauryl sulfate 1.5, hydroxyethyl cellulose 0.5, ethyl hydroxybenzoate 0.05, Oleum menthae 0.5, tetrasodium pyrophosphate 0.5, coreopsis tinctoria extract 1.2, Radix Ginseng extract 0.2, Ganoderma extract 0.2, Herba Dendrobii extract 0.2, Folium Et Cacumen Murrayae extract 0.2, surplus is deionized water composition.After these 5 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound recipe snow chrysanthemum health-care toothpaste.
Example 2:
Compound recipe snow chrysanthemum health-care toothpaste is by calcium hydrogen phosphate 50, sorbitol 20, glycerol 5, sodium lauryl sulfate 1.5, hydroxyethyl cellulose 0.7, ethyl hydroxybenzoate 0.06, Oleum menthae 0.8, tetrasodium pyrophosphate 0.7, coreopsis tinctoria extract 2, Radix Ginseng extract 3, Ganoderma extract 1, Herba Dendrobii extract 1, Folium Et Cacumen Murrayae extract 1, surplus is deionized water composition.After these 5 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound recipe snow chrysanthemum health-care toothpaste.
Example 3:
Compound recipe snow chrysanthemum health-care toothpaste is by sorbitol 50, silicon dioxide 20, glycerol 10, sodium lauryl sulfate 1.5, sodium carboxymethyl cellulose 0.8, ethyl hydroxybenzoate 0.15, Oleum menthae 0.8, tetrasodium pyrophosphate 0.7, coreopsis tinctoria extract 5, Radix Ginseng extract 2, Ganoderma extract 3, Herba Dendrobii extract 3, Folium Et Cacumen Murrayae extract 2, surplus is deionized water composition.After these 5 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water base mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound recipe snow chrysanthemum health-care toothpaste.
Example 4:
Compound recipe snow chrysanthemum health-care toothpaste is by silica 15, sorbitol 60, propylene glycol 5, sodium lauryl sulfate 1.8, hydroxyethyl cellulose 0.8, xanthan gum 0.4, carrageenan 0.3, sodium benzoate 0.3, Oleum menthae 1, calcium hydrogen phosphate 1, coreopsis tinctoria extract 10, Radix Ginseng extract 5, Ganoderma extract 2, Herba Dendrobii extract 2, Folium Et Cacumen Murrayae extract 1, surplus is deionized water composition.After these 5 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound recipe snow chrysanthemum health-care toothpaste.
Example 5:
Compound recipe snow chrysanthemum health-care toothpaste is by silica 18, sorbitol 65, propylene glycol 5; sodium N-lauroyl sarcosinate 2, hydroxyethyl cellulose 0.9, xanthan gum 0.6; ethyl hydroxybenzoate 0.15, tetrasodium pyrophosphate 0.9, Mentholum 2; coreopsis tinctoria extract 6; Radix Ginseng extract 6, Ganoderma extract 3, Herba Dendrobii extract 5; Folium Et Cacumen Murrayae extract 5, surplus is deionized water composition.After these 5 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound recipe snow chrysanthemum health-care toothpaste.
The invention is not limited in above-mentioned embodiment; anyone should learn the dosage or formula made under the enlightenment of the present invention; also be that those skilled in the art obviously change, every have with the present invention same or like as technical scheme formula, belong in protection scope of the present invention.
Claims (5)
1. a compound recipe snow chrysanthemum health-care toothpaste, this toothpaste cream base is by abrasivus, wetting agent, foaming agent, adhesive, aromatic, efficacy active component Chinese herbal medicine extract includes: coreopsis tinctoria extract, Radix Ginseng extract, Ganoderma extract, Herba Dendrobii extract, Folium Et Cacumen Murrayae extract, preservative, corrosion inhibiter and deionized water composition.
One compound recipe the most of the present invention snow chrysanthemum health-care toothpaste, it is characterized in that: described coreopsis tinctoria extract is the xeraphium of snow chrysanthemum ethanol extraction, Radix Ginseng extract is the xeraphium of Radix Ginseng ethanol extraction, Ganoderma extract is the xeraphium of Ganoderma ethanol extraction, Herba Dendrobii extract is the xeraphium of Herba Dendrobii ethanol extraction, Folium Et Cacumen Murrayae extract is the xeraphium of Folium Et Cacumen Murrayae ethanol extraction, these five kinds of Chinese herbal medicine extracts have heat-clearing and toxic substances removing, inhibiting bacteria and diminishing inflammation, reducing swelling and alleviating pain, nourishing YIN to relieve dryness, promoting the production of body fluid and inducing sedation of the mind, dispel halitosis, anti-treating dental ulcer and the effect of prophylaxis of teeth disease, it is added in toothpaste cream base, it is and the reasonable compatibility of toothpaste cream base, it it is preferable effective health Chinese herbal toothpaste.
One compound recipe the most of the present invention snow chrysanthemum health-care toothpaste, it is characterised in that: described cream base includes:
Abrasivus, accounting for the percentage by weight in toothpaste cream base is 20%-50%, can be selected for calcium carbonate, calcium hydrogen phosphate, silicon dioxide, sodium aluminosilicate, aluminium hydroxide and combinations thereof；
Wetting agent, accounting for the percentage by weight in toothpaste cream base is 20% ~ 70%, can be selected for sorbitol, glycerol, propylene glycol, xylitol and combinations thereof；
Foaming agent, accounting for the percentage by weight in toothpaste cream base is 1% ~ 3%, can be selected for sodium lauryl sulfate, sodium N-lauroyl sarcosinate, sodium lauroyl glutamate, lauroyl sulfoacetic acid sodium and combinations thereof；
Adhesive, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 2%, can be selected for sodium carboxymethyl cellulose, hydroxyethyl cellulose, xanthan gum, carrageenan, guar gum and combinations thereof；
Aromatic, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 3%, can be selected for Oleum Menthae Rotundifoliae, Oleum menthae, wintergreen oil, Oleum Caryophylli, Oleum Anisi Stellati, Oleum Cinnamomi, Cladrastis kentukea Rudd oil, orange oil and combinations thereof；
Efficacy active component Chinese herbal medicine extract includes: coreopsis tinctoria extract, and accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 30%；Radix Ginseng extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Ganoderma extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Herba Dendrobii extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Folium Et Cacumen Murrayae extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；
Preservative, accounting for the percentage by weight in toothpaste cream base is 0.05% ~ 1.5%, can be selected for sodium benzoate, methyl hydroxybenzoate, ethyl hydroxybenzoate, butoben and combinations thereof；
Corrosion inhibiter, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 2%, can be selected for sodium silicate, calcium hydrogen phosphate, disodium hydrogen phosphate, tertiary sodium phosphate, tetrasodium pyrophosphate, potassium nitrate and combinations thereof；
Surplus is deionized water.
One compound recipe the most of the present invention snow chrysanthemum health-care toothpaste, it is characterized in that: described coreopsis tinctoria extract, Radix Ginseng extract, Ganoderma extract, Herba Dendrobii extract, Folium Et Cacumen Murrayae extract, these five kinds of Chinese herbal medicine extracts are not limited to the xeraphium as avenged chrysanthemum ethanol extraction, can also be used with supercritical extract, ultrasonic extraction thing, extracting solution, extractum extract, ground product, existing commercially available Chinese medicine extract can also be used, if be applied in toothpaste by other forms such as extracting solution or extractum, addition in formula should be converted to the addition of extract in the formula that disclosed in this invention.
One compound recipe the most of the present invention snow chrysanthemum health-care toothpaste, it is characterized in that: without essence, pigment in toothpaste cream base, this product compound recipe snow chrysanthemum health-care toothpaste has natural Chinese medicinal herb plant fragrance taste and taste of Chinese medicine, there are the stock solution true qualities of natural Chinese medicinal herb, have no side effect, be the health Chinese herbal toothpaste of the conjunction of natural vegetable Chinese herbal medicine and toothpaste cream base.
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Cited By (5)
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| CN106619332A (en) * | 2017-03-02 | 2017-05-10 | 山西锦波生物医药股份有限公司 | Palmitoyl pentapeptide-containing biological curing toothpaste and production method thereof |
| CN106798697A (en) * | 2017-03-02 | 2017-06-06 | 山西锦波生物医药股份有限公司 | A kind of biological toothpaste for nursing and its production method containing recombinant human epidermal growth factor |
| CN106798696A (en) * | 2017-03-02 | 2017-06-06 | 山西锦波生物医药股份有限公司 | A kind of biological toothpaste for nursing and its production method containing recombination human source collagen |
| CN108524404A (en) * | 2018-07-11 | 2018-09-14 | 安徽人民健康生物科技有限公司 | A kind of sealwort herbaceous toothpaste |
| CN113101243A (en) * | 2020-01-09 | 2021-07-13 | 好维股份有限公司 | Oral soft tissue cell repair promoter, oral care composition and application |
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