Invention content
It is an object of the invention to solve the deficiencies in the prior art, a kind of cationic baby's medical dressing and its preparation are provided
Method can nurse the wound site of baby, the isolation to bacterium, fungi, virus.
In order to achieve the above objectives, the technical solution adopted by the present invention is:
A kind of cation baby's medical dressing, by following raw material(Weight ratio)Composition:
Chitosan quaternary ammonium salt 0.8% ~ 1.8%
Polyhexamethylene guanide 0.1% ~ 0.2%
Co-Q10 0.2% ~ 0.7%
Ceramide 0.1% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Apricot kernel oil 0.06% ~ 0.2%
The skin repair factor 0.008% ~ 0.012%
Glycerine 8% ~ 15%
Peppermint oil 0.2% ~ 0.4%
Purify water surplus.
Water speed dissolved cation chitosan quaternary ammonium salt has good antibiotic property, film forming, Cation adsorption, moisture-absorbing moisture-keeping
The performances such as property, flocculability, antistatic property.Its anti-microbial property is better than chitosan and other chitosan derivatives.Chitosan quaternary ammonium salt
It after being dissolved in water, ionizes, a large amount of level Four ammonium cation is contained in solution.Ammonium cation has one to bacterium, fungi, virus
Determine fragmentation effect.
Secondly polyhexamethylene guanide has broad-spectrum;Effective concentration is low;Work fast;Property is stablized;It is soluble easily in water
Excellent performance;It can use at normal temperatures;It is long-term antibacterial, without side-effects;Polyhexamethylene guanide is polyguanidine family macromolecule polymer,
Ionization can be generated in aqueous solution, its hydrophilic base section contains strong electropositive, and absorption is usually in electronegative all kinds of thin
Bacterium, virus into cell membrane, inhibit the synthesis of film lactones plastid, cause thalline apoptosis, reach best bactericidal effect.
Chitosan quaternary ammonium salt, polyhexamethylene guanide generate and form cation, and bacterium, fungi and virus can be carried out
It kills and is isolated.
Glycerine, i.e. glycerine is colourless sweet clear and bright thick liquid, odorless;There is warm sweet taste.Glycerine can be in draw air
Moisture content to skin moisture-keeping, the moisture content in skin can also be lockked, it not allowed to be lost in.There is moisturizing.To the skin of baby
Skin can play moisturizing, moist effect.
Olive oil has beauty and skin care effect:Olive oil is rich in the squalene splendid with skin affinity and fat needed by human
Acid, absorption is rapid, effectively keeps skin elasticity and moistens;Contained abundant monounsaturated fatty acids and vitamin E in olive oil,
K, A, D etc. and phenols antioxidant, can eliminate facial wrinkles, prevent skin aging, there is skin or hair care and prevention hand and foot from chapping
And other effects, it is the cosmetics and skincare product that " can be eaten ", in addition can resist ultraviolet light with olive oil smearing skin prevents cutaneum carcinoma.Olive
In oily numerous compositions, carrotene and chlorophyll assign olive oil yellow green, and chlorophyll plays metabolism, promotes cell
Growth, accelerating wound healing.
Apricot kernel oil, rich in the micro of protein, unrighted acid, vitamin, inorganic salts, dietary fiber and needed by human body
Element has the function of moistening lung, stomach invigorating, regains one's strength of body, and amygdalin is even more natural anti-cancer active matter.Also containing dimension life
Plain E, wherein based on alpha tocopherol and gama tocopherol.Therefore the oil kind not only has very excellent trophism but also tool
There is good antioxidative stabilizer.Apricot kernel oil at home and abroad cosmetic applications very extensively, cream, milk honey, perfumed soap all makes of it
Natural additive.It increases moisturizing and anti-aging effects for product, and warm fragrance is also increased for product.Apricot kernel oil is rich in
Minerals, protein and various vitamins are a kind of skin care and the splendid vegetable oil of moisturizing effect, suitable for various skins
Matter.It can effectively mitigate skin people and itch phenomenon, eliminate redness, dryness and inflammation.Can stimulate internal system the sagging gland of brain,
Thymus gland and adrenal gland promote cell turnover.
The skin repair factor has repair to skin.Can improve the microenvironment of cell growth, promote elastomer and
The synthesis of collagen makes skin high resilience, and skin is made to be in sliding tender state.
Co-Q10 Co-Q10 is a kind of fat-soluble antioxidant, the nutrition of energy human activin cell and cellular energy, tool
It is improved body immunity, enhances the functions such as anti-oxidant, anti-aging and enhancing human activity, be medically widely used in angiocarpy
Systemic disease uses it for nutrient and healthcare products and food additives extensively both at home and abroad.Co-Q10(Coenzyme Q10)It is also known as general
Quinone(Ubiquinone, abridge UQ), it is a kind of fat-soluble quinones for being present in nature, structure and vitamin K, dimension
Raw element E is similar to plastoquinone.Human body participate in into the cell energy manufacture and activation, be prevention of arterial harden to be formed it is most effective
Anti-oxidant composition.Ubiquinone is present in most eukaryocytes, especially mitochondria.It is one of respiratory chain component;It is online
Content on mitochondrial membrane is significantly larger than the content of respiratory chain other components, and fat-soluble makes it on inner membrance with height
Mobility, particularly suitable as a kind of electron transit mediator of flowing.
Co-Q10 is main there are two acting in vivo, first, being converted into the process of energy in mitochondria in nutriment
In play an important role, second is that there is apparent lipoid peroxidization resistant.It is the energy conversion agent in cell mitochondrial, it is logical
It crosses transfer and transmits electronics and participate in " tricarboxylic acid cycle " generation ATP(Atriphos), i.e., energy factors are for cell metabolism use.
Co-Q10 is effective antioxidant and free radical scavenger, it embeds online grain as the component part of mitochondrial respiratory chain
In internal membrane lipid bimolecular, become alcohol of formula after 2 electronics received from Mitochondria complex I or complex II, then by electronics
Pass to complex III.Internal Co-Q10 becomes alcohol of formula by a large amount of consumption, it is both effective antioxidant, while is also fortune
Dynamic electron carrier, hydrogen atom is given to lipid peroxidation free radical by it from its hydroxyl, thus reduces the lipid of mitochondrial inner membrane
Peroxide reactions.Generate in the process with the general semiquinone of the out-of-proportion free radical of the alcohol of formula of Co-Q10 and Co-Q10,
Or react with oxygen and to form superoxides, the general semiquinone of free radical turns under the action of superoxide dismutase and catalase
It transports free radical and realizes detoxication, the respiratory chain that so moves in circles is constantly regenerating into alcohol of formula by Co-Q10, has restored the anti-of it
Anti-oxidant active acts on.
Peppermint oil, can improve the skin of unclean obstruction, and refrigerant feeling can shrink capilary, releive and itch, send out
It is scorching and burn, also can soft skin, for removing blackhead and oily skin also great effect.
Peppermint oil has inhibiting effect to herpes simplex virus, forest virus, mumps virus, to golden yellow Portugal
Grape coccus, staphylococcus albus, alpha streptococcus, beta streptococcus, micrococcus catarrhalis, enteritis coccus, shigella flexneri, anthrax
Bacillus, corynebacterium diphtheriae, typhoid bacillus, Pseudomonas aeruginosa, Escherichia coli etc. have bacteriostasis;Water-soluble peppermint oil can stimulate neural end
The cold receptor of the tip and generate creeping chill, and reflectivity cause the variation of deep tissue blood vessel and play anti-inflammatory, analgesic, antipruritic
Effect.
Ceramide is also known as sphingolipid, is a kind of lipid for being present in skin, in epidermal keratinocytes layer formation process
It plays an important role., when drying, furfur, cracking phenomena occurs in skin, when barrier function is substantially reduced, skin supplement is refreshing
It can restore moisturizing and barrier function rapidly through amide.
Cause have dry skin main cause be in horny layer of epidermis ceramide content reduce, ceramide content height with
Skin dryness is directly related.Adhesion strength between keratinocyte can be remarkably reinforced using ceramide, improve dry skin journey
Degree reduces desquamation of skin phenomenon.Ceramide has hydrone ability of associating by force very much, it in cuticula by forming netted knot
Structure maintains moisture of skin.Therefore, ceramide, which has, keeps moisture of skin effect.It can be made in horny layer of epidermis using ceramide
Ceramide content increases, and can improve the situations such as dry skin, furfur, coarse;Ceramide can increase horny layer of epidermis simultaneously
Thickness improves skin moisture holding capacity, reduces wrinkle, enhances skin elasticity, delay skin aging.
Ceramide is a kind of water-soluble lipid matter, it is close with the structure of matter for forming keratoderma, can be quickly
The water penetrated into skin and cuticula combines, and forms a kind of reticular structure, locks moisture.
When the skin small area of infant is by wound infection, such as the red arm of infant, bite by mosquitos, burn and scald, prickly heat, water
Acne, diaper rash, eczema, nettle rash, scabies etc..Since the skin of infant is tenderer, self-repairing capability is weaker, by wound
Afterwards, easy scar.Therefore infant's skin site of injury, repairs skin, its main effect is skin in reparation
Reparative factor promotes the synthesis of elastomer and collagen, while being repaired to skin, to avoid the skin of new connective
The mode of appearance difference of skin tissue is larger;Using the combination of olive oil and apricot kernel oil to that, into smearing, can cause at skin trauma
The skin skirt of wound keeps moist and elasticity so that the skin histology newly grown will not be because of water shortage point, chromogenesis;Form scar
Trace.Antibody in infants is less, is easily infected by after wound, therefore the processing that carries out disinfection, in the technical program
Using the combination of chitosan quaternary ammonium salt, polyhexamethylene guanide, since the bactericidal properties of polyhexamethylene guanide are stronger, and have centainly
Toxicity;Therefore, the content of polyhexamethylene guanide is relatively low, it is preferable that chitosan quaternary ammonium salt content is more than polyhexamethylene guanide content
7 times, and polyhexamethylene guanide content be no more than 0.2%.During skin repair, need skin moisture-keeping and moisten, avoid water
Shunting is lost;Moisturizing is carried out using glycerine in the technical program and is moistened.The content of glycerine is preferably no less than 8%.Skin is created
After wound, some dead skin tissues may block the pore of neoplastic skin tissue, need to be purged it;Synkaingenesis skin histology
Certain pain and gargalesthesia can be generated;Skin is cleared up using peppermint oil, at the same can play it is certain relieve pain, antipruritic effect
Fruit.The ingredient of skin mainly has grease, and after wound, the oil fraction of skin corium can expose to air, is vulnerable to oxidation and becomes
Color;Co-Q10 can effectively play antioxidant effect.Secondly, ceramide can play certain antiallergy, keep skin
The effect of moisture so that neoplastic skin tissue can effectively keep moisture, avoid drying, pigementation.
Preferably, the content summation of chitosan quaternary ammonium salt and polyhexamethylene guanide is no more than 1.95%.Two kinds of ingredients are killing
While bacterium, the leucocyte in Skin Cell and skin histology may be hurt;By clinical trial analysis, when its weight surpasses
A timing is crossed, influences whether that leucocyte works.
Preferably, a kind of cationic baby's medical dressing, by following raw material(Weight ratio)Composition:
Chitosan quaternary ammonium salt 1% ~ 1.8%
Polyhexamethylene guanide 0.15% ~ 0.2%
Co-Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.5%
Olive oil 0.08% ~ 0.12%
Apricot kernel oil 0.07% ~ 0.12%
The skin repair factor 0.009% ~ 0.01%
Glycerine 9% ~ 12%
Peppermint oil 0.2% ~ 0.4%
Purify water surplus.
More preferably, a kind of cationic baby's medical dressing, by following raw material(Weight ratio)Composition:
Chitosan quaternary ammonium salt 1.5%
Polyhexamethylene guanide 0.2%
Co-Q10 0.5%
Ceramide 0.3%
Olive oil 0.1%
Apricot kernel oil 0.1%
The skin repair factor 0.01%
Glycerine 10%
Peppermint oil 0.3%
Purify water surplus.
A kind of preparation method of above-mentioned cationic baby's medical dressing, including:
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, Co-Q10, ceramide, olive oil,
Apricot kernel oil, the skin repair factor, glycerine, peppermint oil;
Step 2: weigh the purified water of formula ratio;
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Preferably, a kind of cationic baby's medical dressing, by following raw material(Weight ratio)Composition:
Chitosan quaternary ammonium salt 1.0% ~ 1.8%
Polyhexamethylene guanide 0.15% ~ 0.2%
Co-Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Apricot kernel oil 0.06% ~ 0.2%
The skin repair factor 0.01%
Glycerine 8% ~ 15%
Peppermint oil 0.2% ~ 0.4%
Aloin 0.8% ~ 1%
Purify water surplus.
Aloin can help to discharge internal dirt, purification blood, softening blood vessel, reduce blood pressure and blood viscosity, promote blood
Liquid recycles;Mixture of the active constituent based on barbaloin is dicotyledon aloe extract.Bactericidal effect, anti-inflammatory effect,
Beautification function is moistened, the effect of letting out under stomach invigorating, cardiac stimulant promoting blood circulation effect, is immunized and palingenesis, immune and antitumor action, removing toxic substances are made
With, anti-aging effects, analgesia, sedation, anti-sunlight function.The polysaccharide and multivitamin contained in aloe has human skin good
Nutrition well is moistened, whitening effect.Aloe barbadensis Miller is the Fresh leaf of aloe of the direct beauty of optimum, i.e. aloe barbadensis Miller, it has
Make skin contraction, softness, moisturizing, anti-inflammatory, the performance bleached.Hardening, angling, the effect for improving scar are also released, not only
It can prevent small wrinkle, pouch, cutis laxa, moreover it is possible to skin wet, delicate is kept, at the same time it can also treat scytitis, to powder
Thorn, freckle, acne and scald, knife wound, insect bite etc. also have the effect of fine.It is similarly effective to hair, hair can be kept
Moisten smooth, pre-Anti-hair loss.
When the skin of infant is by wound, sometimes along with bleeding;Especially scald, it can also be along with inflammation;It is applying
Increase a certain amount of aloin in material, certain haemostatic effect and antibacterial, anti-inflammatory can be played;By clinical test, not with its
His drug ingedient conflict.
A kind of preparation method of above-mentioned cationic baby's medical dressing, including:
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, Co-Q10, ceramide, olive oil,
Apricot kernel oil, the skin repair factor, glycerine, peppermint oil, aloin;
Step 2: weigh the purified water of formula ratio;
The formula of step 1 is poured into purified water and mixed by step 3 successively.
It is further preferred that a kind of cation baby's medical dressing, by following raw material(Weight ratio)Composition:
Chitosan quaternary ammonium salt 1.0% ~ 1.8%
Polyhexamethylene guanide 0.15% ~ 0.2%
Co-Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Apricot kernel oil 0.06% ~ 0.2%
The skin repair factor 0.01%
Glycerine 8% ~ 15%
Peppermint oil 0.2% ~ 0.4%
Aloin 0.8% ~ 1%
Hydrogen peroxide 1% ~ 2%
Purify water surplus.
Hydrogen peroxide has preferable oxidation effectiveness, using low concentration(Especially weight ratio is less than 3%)Hydrogen peroxide and skin
Wound, fester or dirt when meeting, decompose generation oxygen immediately.This oxygen atom for being not yet combined into oxygen molecule has very strong
Oxidability, when being contacted with bacterium, microorganism can be destroyed, kill bacterium.An aerobic environment can be provided simultaneously, is killed
The collagen of anaerobic bacteria and aid in skin is formed.Here the content of hydrogen peroxide refers to:Weight of the hydrogen peroxide in entire dressing
Measure content:1%~2%.
A kind of preparation method of above-mentioned cationic baby's medical dressing, including:
Step 1: weigh the chitosan quaternary ammonium salt of formula ratio, polyhexamethylene guanide, Co-Q10, ceramide, olive oil,
Apricot kernel oil, the skin repair factor, glycerine, peppermint oil, aloin, hydrogen peroxide;
Step 2: weigh the purified water of formula ratio;
The formula of step 1 is poured into purified water and mixed by step 3 successively.
Since 100% hydrogen peroxide of content is difficult to obtain, the hydrogen peroxide for the quality such as the hydrogen peroxide in step 1 uses, other are dense
Hydrogen peroxide is spent to substitute;That is step 1 when with hydrogen peroxide is taken, can match other concentration hydrogen peroxide for taking equivalent, such as contain with taking
Measure 30% hydrogen peroxide of hydrogen peroxide(Quality containing hydrogen peroxide is equal);Step 2 replaces with:Weigh the purified water of surplus.
Beneficial effects of the present invention are:
1), using chitosan quaternary ammonium salt, polyhexamethylene guanide etc. have bactericidal effect to skin trauma position, avoid feeling again
Dye;
2), skin trauma position can be maintained using glycerine, olive oil, apricot kernel oil etc., avoid skin from wound portion
Bit loss moisture.
3), secondly, using repair ingredient, skin is repaired, avoids the occurrence of scar.
Fast skin reparation is can reach, and does not leave scar.It can be widely applied to the red stern of infant, prickly heat, varicella, diaper
The treating skin diseases such as rash, eczema, nettle rash, scabies, bleb;To skin, scratch, wound, scald, burn, bite by mosquitos etc.
Also there is good therapeutic effect.