CN105168807B - The Chinese medicine composition and preparation method thereof for treating pig blue-ear disease - Google Patents
The Chinese medicine composition and preparation method thereof for treating pig blue-ear disease Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides the preparation methods of a kind of Chinese medicine composition for treating pig blue-ear disease and the Chinese medicine composition.Belong to veterinary medicament field, the composition is mainly made of the bulk pharmaceutical chemicals of following parts by weight: 10~25 parts of Gorgon fruit, 8~10 parts of Fructus Forsythiae, 5~9 parts of the coptis, 7~13 parts of radix bupleuri, 10~20 parts of radix glycyrrhizae preparata, 9~16 parts of Radix Paeoniae Alba, 6~10 parts of garlic, 20~30 parts of plant polyose, the plant polyose are mixed to prepare by aloe polysaccharide, astragalus polyose and Codonopsis pilosula polysaccharide according to 8~15:7 of mass ratio~10:5~8.Drug of the present invention has clearing heat-fire, the functions such as anti-inflammatory, antibacterial, addition plant polyose can effectively provide the immunity of pig, reduce blue otopathy disease incidence, the present invention can add vitamin C, the advantages that promotion growth, prevention and control disease, and the composition preparation method is simple, securely and reliably, pollution-free, noresidue is easy to spread.
Description
Technical field
The invention belongs to veterinary medicament field, in particular to a kind of Chinese medicine composition for treating pig blue-ear disease and the Chinese medicine group
Close the preparation method of object.
Background technique
Porcine reproductive and respiratory syndrome, also known as blue otopathy are a kind of pig breathing caused by virus and breeding difficulty
Disease, is a kind of worldwide Infectious Diseases of pig breeding industry, and high mortality and high infectious rate are brought seriously to pig farm
Economic loss.Pig is unique host of pig blue-ear disease, and the pig under various ages, kind and various rearing conditions can infect,
But its neurological susceptibility of the pig of all ages and classes has different, and grower pigs and the metainfective symptom of fattening pig are milder, and gestation is female
Pig and piglet within 1 monthly age are most susceptible, and symptom is then more serious, and sucking pig case fatality rate is up to 80%~100%.Illness pig and band
Malicious pig is the important infection sources of this disease.Major transmission path is that contact infection, air borne and sperm are propagated, and can also pass through placenta
Vertical transmission, the pig with pig blue-ear disease are mainly shown as the production performance decline of swinery, slow growth, the reproductive ability of sow group
It can decline, Swinery immunity function reduction, other bacillary and viral diseases of easy secondary infection.The respiratory disease of swinery is (such as
Mycoplasma infection, contagious pleuropneumonia, streptococcosis, eperythrozoonosis) disease incidence rising.The pathogenic factor of pig blue-ear disease
The destruction for essentially consisting in the immune function of pig causes to infect, and therefore, the effective way for the treatment of should be susceptible to virus from body is improved
The immune function of dye cell is started with.
Currently, the method for prevention and treatment pig blue-ear disease is more, mainly prevented and treated using Western medicine, immunoprophylaxis, Chinese herbal medicine etc..
Wherein, what Western medicine used, which spread unchecked, brings great security risk to pork based food, and medicament residue has become influence pork
One of principal element of product safety.Immunoprophylaxis early stage results are preferable, but need repeatedly inoculation, troublesome in poeration, Er Qiecheng
This is higher, be easy to cause stress reaction；And there is dispute in clinical use in vaccine inoculation, and it can not large-scale promotion.Medium-height grass
Medicine feed addictive is current research direction.But to there is medicine more in current Chinese herbal feed additive preparation effect is paid no attention to
Think therefore the problems such as treatment is slow, and the course for the treatment of is long, and cure rate is low, improves the curative effect of the Chinese herbal feed additive for the treatment of pig blue-ear disease
It is still a great problem of this field.
Summary of the invention
The present invention is to solve the problems, such as that treatment pig blue-ear disease Chinese herb feed additive therapeutic effect is bad in the prior art, provides
A kind of Chinese medicine composition and preparation method thereof that treating pig blue-ear disease, it is blue by way of feeding the composition to be applied to pig
The prevention and control of otopathy reach the double effects of prevention and control indigo plant otopathy and strengthen immunity, reduce the disease incidence of pig blue-ear disease.
In order to achieve the above objectives, the present invention is implemented as follows: a kind of Chinese medicine composition for treating pig blue-ear disease, the combination
Object is mainly made of the bulk pharmaceutical chemicals of following parts by weight: 10~25 parts of Gorgon fruit, 8~10 parts of Fructus Forsythiae, 5~9 parts of the coptis, radix bupleuri 7~13
Part, 10~20 parts of radix glycyrrhizae preparata, 9~16 parts of Radix Paeoniae Alba, 6~10 parts of garlic, 20~30 parts of plant polyose, the plant polyose is by reed
Luxuriant growth polysaccharide, astragalus polyose and Codonopsis pilosula polysaccharide are mixed to prepare according to 8~15:7 of mass ratio~10:5~8；
Following extracting method is respectively adopted in aloe polysaccharide, astragalus polyose and the Codonopsis pilosula polysaccharide: raw material is cleaned up,
After crushing, extraction, concentration, into concentrate be added citric acid and ethyl alcohol mixed liquor, concentrate, citric acid and ethyl alcohol according to
The volume ratio of 2:1:1 is added；Microwave Extraction is carried out after mixing, microwave irradiating time 30s~50s, microwave power 700W are filtered,
With active carbon decoloring, up to product after concentration.
The dosage of drug component of the invention is to be obtained by plenty of explorations of the inventor, and each component is in following weight
Part lower have a good therapeutic effect, 15 parts of Gorgon fruit, 9.5 parts of Fructus Forsythiae, 7.5 parts of the coptis, 10 parts of radix bupleuri, 12 parts of radix glycyrrhizae preparata, 10.5 parts of Radix Paeoniae Alba,
6.5 parts of garlic, 28 parts of plant polyose.
Preferably, the plant polyose is mixed by aloe polysaccharide, astragalus polyose and Codonopsis pilosula polysaccharide according to mass ratio 13:8:7
It closes and is made.
Drug each component of the present invention may also is that 10~25 parts of Gorgon fruit, 8~10 parts of Fructus Forsythiae, 5~9 parts of the coptis, radix bupleuri 7~
13 parts, 10~20 parts of radix glycyrrhizae preparata, 9~16 parts of Radix Paeoniae Alba, 6~10 parts of garlic, 20~35 parts of plant polyose, 3~9 parts of vitamin C.
More preferably 15 parts of Gorgon fruit, 9.5 parts of Fructus Forsythiae, 7.5 parts of the coptis, 10 parts of radix bupleuri, 12 parts of radix glycyrrhizae preparata, 10.5 parts of Radix Paeoniae Alba,
6.5 parts of garlic, 28 parts of plant polyose, 7.5 parts of vitamin C.
Medicament selection Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic, Fructus Forsythiae, the coptis and plant polyose and vitamin C of the present invention
It is combined, so that each medicine effect is generated synergistic effect these pharmaceutical compositions, so as to effectively treat pig blue-ear disease.It is wherein yellow
Company is chiefly used in the diseases such as damp and hot retention of damp-heat in the interior, stomach, vomiting, dysentery, is used for warm disease high fever, thirsty agitation, blood-heat bleeding, Yi Jire
Carbuncle ulcer etc., main component jamaicin fight bacteriotoxin, reduce staphylococcus aureus coagulase, hemolysin potency, drop
The virulence of low Escherichia coli, is used cooperatively with saikoside, to typhoid fever, paratyphoid vaccine, Escherichia coli liquid, fermented milk,
Fever caused by yeast etc. has obvious refrigeration function；And animal normal body temperature can be made to decline.Meanwhile saikosaponin saikoside, have and promotes to exempt from
The effect of epidemic disease function, improves special viral antibody titre, improves lymphocyte and turns core rate, it is anti-to improve skin delayed type hypersensitivity
It answers.Radix glycyrrhizae preparata contains a variety of chemical components such as glycyrrhizin, enoxolone, licorice polysaccharide, and there is anti-inflammatory and antiallergic action to make
With, adjustable body's immunity, antitumor and analgesic effect.The Paeoniflorin contained in Radix Paeoniae Alba has antibacterial, antipyretic, anti-inflammatory, increasing
Add coronary flow, improves myocardial nutritional flow, expansion blood vessel, confrontation acute myocardial ischemia, inhibits platelet aggregation, town
Quiet, analgesia, spasmolysis, antiulcer, the effect for adjusting blood glucose.Aloe polysaccharide, the astragalus polyose of purity is high are obtained by Microwave Extraction
And Codonopsis pilosula polysaccharide, being added to its main active in traditional Chinese medicinal components after mixing can after mixing with each taste monarch drug in a prescription
To play one's part to the full, have the function of that good scavenging activated oxygen, especially aloe polysaccharide can be adjusted with Codonopsis pilosula polysaccharide
The immunity of body.
To reach better curative effect, the present invention also selects Gorgon fruit, garlic, Fructus Forsythiae to be combined, because Gorgon fruit is mild-natured, taste
It is sweet, puckery.There are tonifying spleen and stopping diarrhea, the function of tonifying spleen and stopping diarrhea, carbohydrate containing is extremely abundant, and it is fatty seldom, thus be easy to
It is absorbed.The effect of garlic has removing toxic substances desinsection, swelling and pain relieving, and antidiarrheal stop dysentery controls lung, expelling parasite, in addition there are warm spleen warm stomaches；Even
Heat-clearing is stuck up, is detoxified, dissipating bind, detumescence.Control warm, erysipelas, macula, large carbuncle pyogenic infections and other effects.To obtain optimum efficiency, the present invention exists
It is also added into vitamin C on the basis of said medicine, may participate in the immune response of matrix.
The preparation method of the Chinese medicine composition of above-mentioned treatment pig blue-ear disease is also claimed in the present invention, comprising the following steps:
(1) 10~25 parts of Gorgon fruit, 7~13 parts of radix bupleuri, 10~20 parts of radix glycyrrhizae preparata, 9~16 parts of Radix Paeoniae Alba, garlic 6~10 are weighed
Part, 8~10 parts of Fructus Forsythiae and 5~9 parts of the coptis, impurity elimination is dried；
(2) Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic are soaked in water 15~45 minutes, amount of water is not cross powder
Preferably, decocted 2~4 hours prior to 90~100 DEG C, by medical filtration, then at 40~50 DEG C decoction filtrate 1~1.5 hour, be centrifuged
Filter to obtain medical fluid I；
(3) water that Fructus Forsythiae, the coptis crush 8~10 times of volumes of addition is cooked 1~3 hour in 90~100 DEG C, is then used again
90%~95% alcohol reflux of mass concentration extracts, and extracting solution is filtered, it is stand-by to obtain medical fluid II by ethyl alcohol recycling；
(4) by the aloe polysaccharide of extraction, astragalus polyose and Codonopsis pilosula polysaccharide, 8~15:7~10:5~8 is mixed according to the proportion
It is even to obtain plant polyose；
(5) medical fluid I is mixed with medical fluid II, is added 20~35 parts and 3~9 parts of vitamin C of plant polyose, stirs evenly,
It is cooked 0.5~1 hour in 50~60 DEG C, in 45~50 DEG C of dryings, is crushed into powder, obtains Chinese medicine composition.
The Chinese medicine composition for the treatment of pig blue-ear disease of the present invention can be made pharmaceutically acceptable dose any
Type, spray, granule or decoction.
Drug of the present invention can be prepared into any conventional oral preparations using the conventional method of Chinese materia medica preparation.Such as it can will be former
Material medicine grind into powder, which is uniformly mixed, to be made powder and takes after mixing it with water, and can then decocting liquid be concentrated in raw material material decocting, but in order to make this
Each raw material of drug preferably plays drug effect, preferably carries out Microwave Extraction to the plant polyose in raw material, and Fructus Forsythiae, the coptis carry out second
Alcohol extracting.
Various customary adjuvants required when preparing different dosage forms can be added in composition of the invention, such as lubricant, bonding
Agent etc. is prepared into any common formulations with conventional method of Chinese medicinal, such as spray, granule or decoction.
The beneficial effects of the present invention are: drug of the present invention has clearing heat-fire, it is more to add plant for the functions such as anti-inflammatory, antibacterial
Sugar can effectively provide the immunity of pig, reduce blue otopathy disease incidence, and the present invention can add vitamin C, promote growth, prevention and control disease
The advantages that sick, and the composition preparation method is simple, and securely and reliably, pollution-free, noresidue is easy to spread.
Specific embodiment
The preparation method and beneficial effect of the present invention is further explained the by the following examples drug.
Aloe polysaccharide, astragalus polyose and Codonopsis pilosula polysaccharide are all made of following extracting method: raw material cleaned up, crushed,
After extraction, concentration, the mixed liquor of citric acid and ethyl alcohol is added into concentrate, concentrate, citric acid and ethyl alcohol are according to 2:1:1's
Volume ratio addition；Microwave Extraction, microwave irradiating time 30s~50s, microwave power 700W are carried out after mixing, active carbon is used in filtering
Decoloration, up to product after concentration.
Embodiment 1
15 grams of Gorgon fruit, 9.5 grams of Fructus Forsythiae, 7.5 grams of the coptis, 10 grams of radix bupleuri, 12 grams of radix glycyrrhizae preparata, 10.5 grams of Radix Paeoniae Alba, garlic 6.5
Gram, 28 grams of plant polyose and 7 grams of vitamin C.
28 grams of plant polyose are mixed to prepare by 13 grams of aloe polysaccharides, 8 grams of astragalus polyoses and 7 grams of Codonopsis pilosula polysaccharides.
(1) suitable Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic, Fructus Forsythiae, the coptis are weighed, impurity elimination is dried；
(2) Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic are soaked in water 15~45 minutes, amount of water is not cross powder
Preferably, decocted 2 hours prior to 100 DEG C, by medical filtration, then at 50 DEG C decoction filtrate 1.5 hours, centrifugal filtration obtains medical fluid I；
(3) water that Fructus Forsythiae, the coptis crush 10 times of volumes of addition is cooked 1 hour in 100 DEG C, then uses mass concentration again
95% alcohol reflux extracts, and extracting solution is filtered, it is stand-by to obtain medical fluid II by ethyl alcohol recycling；
(4) aloe polysaccharide of extraction, astragalus polyose and Codonopsis pilosula polysaccharide are uniformly mixed according to the proportion and obtain plant polyose；
(5) medical fluid I is mixed with medical fluid II, plant polyose and vitamin C is added, stirs evenly, it is small to cook 1 in 60 DEG C
When, in 50 DEG C of dryings, it is crushed into powder, obtains Chinese medicine composition.
Gained Chinese medicine composition is added in deionized water and is dissolved, spray can be obtained using aerosol bottle packaging.
Embodiment 2
10 grams of Gorgon fruit, 10 grams of Fructus Forsythiae, 9 grams of the coptis, 7 grams of radix bupleuri, 20 grams of radix glycyrrhizae preparata, 9 grams of Radix Paeoniae Alba, 6 grams of garlic, plant polyose
20 grams and 3 grams of vitamin C.
20 grams of plant polyose are mixed to prepare by 8 grams of aloe polysaccharides, 7 grams of astragalus polyoses and 5 grams of Codonopsis pilosula polysaccharides.
(1) suitable Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic, Fructus Forsythiae, the coptis are weighed, impurity elimination is dried；
(2) Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic are soaked in water 15~45 minutes, amount of water is not cross powder
Preferably, decocted 4 hours in 90 DEG C, by medical filtration, then at 40 DEG C decoction filtrate 1 hour, centrifugal filtration obtains medical fluid I；
(3) water that Fructus Forsythiae, the coptis are crushed to 8 times of volumes of addition cooks 2 hours in 90 DEG C, then uses mass concentration 95% again
Alcohol reflux extracts, and extracting solution is filtered, it is stand-by to obtain medical fluid II by ethyl alcohol recycling；
(4) aloe polysaccharide of extraction, astragalus polyose and Codonopsis pilosula polysaccharide are uniformly mixed according to the proportion and obtain plant polyose；
(5) medical fluid I is mixed with medical fluid II, plant polyose and vitamin C is added, stirs evenly, it is small to cook 1 in 55 DEG C
When, in 45 DEG C of dryings, it is crushed into powder, obtains Chinese medicine composition.
Gained Chinese medicine composition is ground into fine powder again, ethyl alcohol is added and makees binder, be added starch make filling and, be pressed into
Granule.
Embodiment 3
25 grams of Gorgon fruit, 5 grams of the coptis, 12 grams of radix bupleuri, 10.5 grams of radix glycyrrhizae preparata, 15 grams of Radix Paeoniae Alba, 9 grams of garlic, is planted at 9.5 grams of Fructus Forsythiae
30 grams and 9 grams of vitamin C of object polysaccharide.
30 grams of plant polyose are mixed to prepare by 12 grams of aloe polysaccharides, 10 grams of astragalus polyoses and 8 grams of Codonopsis pilosula polysaccharides.
(1) suitable Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic, Fructus Forsythiae, the coptis are weighed, impurity elimination is dried；
(2) Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic are soaked in water 15~45 minutes, amount of water is not cross powder
Preferably, decocted 3 hours in 100 DEG C, by medical filtration, then at 50 DEG C decoction filtrate 1.5 hours, centrifugal filtration obtains medical fluid I；
(3) water that Fructus Forsythiae, the coptis crush 10 times of volumes of addition is cooked 2 hours in 100 DEG C, then uses mass concentration again
90% alcohol reflux extracts, and extracting solution is filtered, it is stand-by to obtain medical fluid II by ethyl alcohol recycling；
(4) aloe polysaccharide of extraction, astragalus polyose and Codonopsis pilosula polysaccharide are uniformly mixed according to the proportion and obtain plant polyose；
(5) medical fluid I is mixed with medical fluid II, plant polyose and vitamin C is added, stirs evenly, cook 0.5 in 50 DEG C~
It 1 hour, in 45 DEG C of dryings, is crushed into powder, obtains Chinese medicine composition.
Gained Chinese medicine composition is added to dissolve to boil in deionized water, decoction is made.
Embodiment 4
20 grams of Gorgon fruit, 8 grams of Fructus Forsythiae, 8.5 grams of the coptis, 13 grams of radix bupleuri, 10 grams of radix glycyrrhizae preparata, 16 grams of Radix Paeoniae Alba, 10 grams of garlic and plant
26 grams of object polysaccharide.
33 grams of plant polyose are mixed to prepare by 15 grams of aloe polysaccharides, 10 grams of astragalus polyoses and 8 grams of Codonopsis pilosula polysaccharides.
(1) suitable Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic, Fructus Forsythiae, the coptis are weighed, impurity elimination is dried；
(2) Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic are soaked in water 15~45 minutes, amount of water is not cross powder
Preferably, decocted 2 hours in 100 DEG C, by medical filtration, then at 40 DEG C decoction filtrate 1.5 hours, centrifugal filtration obtains medical fluid I；
(3) water that Fructus Forsythiae, the coptis crush 10 times of volumes of addition is cooked 3 hours in 100 DEG C, then uses mass concentration again
90% alcohol reflux extracts, and extracting solution is filtered, it is stand-by to obtain medical fluid II by ethyl alcohol recycling；
(4) aloe polysaccharide of extraction, astragalus polyose and Codonopsis pilosula polysaccharide are uniformly mixed according to the proportion and obtain plant polyose；
(5) medical fluid I is mixed with medical fluid II, plant polyose and vitamin C is added, stirs evenly, it is small to cook 1 in 60 DEG C
When, in 45 DEG C of dryings, it is crushed into powder, obtains Chinese medicine composition.
Gained Chinese medicine composition is added in deionized water and is dissolved, is cooled to room temperature, can must be sprayed using aerosol bottle packaging
Agent.
Test example 1:
1, test grouping: piglet and Adult Pig each 100 of the choosing with blue otopathy amount to 200, male and female dual-purpose is divided into
Piglet group and Adult Pig group are randomly divided into four groups for two groups again, every group 50, wherein two groups as a control group, one group is uses
Etc. quality water blank group, one group for using the treatment comparative group of antibiotic, in addition two groups is use the traditional chinese medicine composition of the invention
The treatment group of different dosage forms drug.
2, diagnostic criteria:
Body temperature is up to 40 DEG C or more, and expiratory dyspnea is in abdominal respiration, appetite stimulator or abolish sometimes, and diarrhea peels off, solely
Place or mutual huddling together, coat is slightly random, muscular tremor, unstable incoordination of walking, four limbs outreach, and posterior paralysis is gradual
Syntexis, palpebral edema.Some piglet performance mouth and nose surprises are itched, and on colony house friction wall column, nose has batter shape or water for common nose disk, mouth end
Sample secretion.
3, treatment method:
10~30ml is administered every time, is used in conjunction 14 days per daily 3~5 times for spray.Granule and decoction are mixed into feed,
It conventionally feeds, each mixed volume is the 0.1~0.2% of total feed quality, is used continuously 14 days, observation in the 15th day is controlled
Treat situation.
4, efficacy assessment standard:
Effective: temperature of pig body is normal, no diarrhea, and breathing is normal, no oedema, and spirit, appetite are normal；
Improve: temperature of pig body is normal, no diarrhea, there is mild respiratory symptom, and spirit, appetite are normal；
It is invalid: improvement standard or death is not achieved.
5, treatment results
Therapeutic effect of 1 Chinese medicine composition of table to pig blue-ear disease
| Group | Dosage g/kg | Invalid head number | Survival rate | Cure rate |
| Control group | Equivalent amount of water | 46 | 8% | 0 |
| Antibiotic group | 10 | 41 | 17% | 13% |
| Medicinal herb spray group | 16.5 | 12 | 76% | 64% |
| Chinese herbal granules group | 15 | 9 | 82% | 74% |
Note: P < 0.01 * * * compared with the control group.
Test example 2
Chinese medicine composition prepared by the present invention is subjected to clinical test.
Clinical test one:
There is fever, diarrhea, dyspnea symptom and adjoint essence in the doubtful illness of piglet in 37 1 monthly ages of Dalian pig farm
Refreshing depressed, loss of appetite phenomenon, Traditional Chinese medicinal spray obtained by the present invention is treated, daily spray 5 times, each 30ml, two weeks
It is as a treatment course, two courses for the treatment of are used continuously, are as shown in table 2 observation of curative effect situation after the treatment of medicinal herb spray group.
Table 2
Clinical test two:
There is fever, diarrhea, dyspnea symptom and adjoint spirit not in the doubtful illness of Adult Pig of 60, Dalian pig farm
Vibration, loss of appetite phenomenon, Chinese medicinal granule obtained by the present invention is treated, is conventionally fed, each mixed volume is
The 0.1% of total feed quality is as shown in table 3 observation of curative effect situation after the treatment of Chinese herbal granules group.
Table 3
Clinical test three:
There is fever, diarrhea, dyspnea symptom and adjoint essence in the doubtful illness of piglet in 42 1 monthly ages of Dalian pig farm
Refreshing depressed, loss of appetite phenomenon, traditional Chinese herbal decoction obtained by the present invention is treated, is conventionally fed, is mixed into every time
Amount is the 0.2% of total feed quality, is as shown in table 4 observation of curative effect situation after the treatment of traditional Chinese herbal decoction group.
Table 4
Taking the piglet of decoction of the present invention its blue otopathy has apparent curative effect, and effective percentage can achieve 90.5%,
And it was found that the Chinese medicine play the role of to piglet it is somatotrophic.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art within the technical scope of the present disclosure, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (5)
1. a kind of Chinese medicine composition for treating pig blue-ear disease, which is characterized in that the composition by following parts by weight bulk pharmaceutical chemicals group
At: 10~25 parts of Gorgon fruit, 8~10 parts of Fructus Forsythiae, 5~9 parts of the coptis, 7~13 parts of radix bupleuri, 10~20 parts of radix glycyrrhizae preparata, Radix Paeoniae Alba 9~16
Part, 6~10 parts of garlic, 3~9 parts of vitamin C, 20~35 parts of plant polyose, the plant polyose is by aloe polysaccharide, Radix Astragali
Polysaccharide and Codonopsis pilosula polysaccharide are mixed to prepare according to 8~15:7 of mass ratio~10:5~8；
Following extracting method is respectively adopted in aloe polysaccharide, astragalus polyose and the Codonopsis pilosula polysaccharide: raw material being cleaned up, through powder
After broken, extraction, concentration, the mixed liquor of citric acid and ethyl alcohol is added into concentrate, concentrate, citric acid and ethyl alcohol are according to 2:1:
1 volume ratio addition；Microwave Extraction, microwave irradiating time 30s~50s, microwave power 700W, filtering, with work are carried out after mixing
Property carbon decoloring, up to product after concentration.
2. the Chinese medicine composition for the treatment of pig blue-ear disease according to claim 1, which is characterized in that each raw material in the composition
The dosage of medicine are as follows: 15 parts of Gorgon fruit, 9.5 parts of Fructus Forsythiae, 7.5 parts of the coptis, 10 parts of radix bupleuri, 12 parts of radix glycyrrhizae preparata, 10.5 parts of Radix Paeoniae Alba, garlic
6.5 parts, 28 parts of plant polyose, 7.5 parts of vitamin C.
3. it is according to claim 1 treatment pig blue-ear disease Chinese medicine composition, which is characterized in that the plant polyose by
Aloe polysaccharide, astragalus polyose and Codonopsis pilosula polysaccharide are mixed to prepare according to mass ratio 13:8:7.
4. a kind of preparation method for the Chinese medicine composition for treating pig blue-ear disease as described in claim 1, which is characterized in that including
Following steps:
(1) it weighs 10~25 parts of Gorgon fruit, 7~13 parts of radix bupleuri, 10~20 parts of radix glycyrrhizae preparata, 9~16 parts of Radix Paeoniae Alba, 6~10 parts of garlic, connect
8~10 parts and 5~9 parts of the coptis are stuck up, impurity elimination is dried；
(2) Gorgon fruit, radix bupleuri, radix glycyrrhizae preparata, Radix Paeoniae Alba, garlic are soaked in water 15~45 minutes, amount of water is advisable with not crossing powder, first
Decocted 2~4 hours in 90~100 DEG C, by medical filtration, then at 40~50 DEG C decoction filtrate 1~1.5 hour, centrifugal filtration obtains
Medical fluid I；
(3) water that Fructus Forsythiae, the coptis crush 8~10 times of volumes of addition is cooked 1~3 hour in 90~100 DEG C, then uses quality again
90%~95% alcohol reflux of concentration extracts, and extracting solution is filtered, it is stand-by to obtain medical fluid II by ethyl alcohol recycling；
(4) by the aloe polysaccharide of extraction, astragalus polyose and Codonopsis pilosula polysaccharide, 8~15:7~10:5~8 are uniformly mixed according to the proportion
To plant polyose；
(5) medical fluid I is mixed with medical fluid II, is added 20~35 parts and 3~9 parts of vitamin C of plant polyose, stirs evenly, in 50
~60 DEG C cook 0.5~1 hour, in 45~50 DEG C of dryings, are crushed into powder, obtain Chinese medicine composition.
5. the preparation method of the Chinese medicine composition for the treatment of pig blue-ear disease according to claim 4, which is characterized in that dosage form
Are as follows: spray, granule or decoction.
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