CN104705326B - A kind of bactericidal composition containing Zhongshengmycin and tiger glue adipic acid copper - Google Patents
A kind of bactericidal composition containing Zhongshengmycin and tiger glue adipic acid copper Download PDFInfo
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- CN104705326B CN104705326B CN201510114222.0A CN201510114222A CN104705326B CN 104705326 B CN104705326 B CN 104705326B CN 201510114222 A CN201510114222 A CN 201510114222A CN 104705326 B CN104705326 B CN 104705326B
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Abstract
The invention discloses a kind of bactericidal composition containing Zhongshengmycin and tiger glue adipic acid copper, its active ingredient is Zhongshengmycin and tiger glue adipic acid copper, and the ratio of weight and number of Zhongshengmycin and tiger glue adipic acid copper is 1:10~10:1, the percentage by weight of Zhongshengmycin and tiger glue adipic acid weight of copper summation in the composition is 4%~97%, bactericidal composition of the present invention can process the one kind being prepared into suspending agent, water dispersible granules, aqueous emulsion, microemulsion, wettable powder, there is outstanding prevention effect to agricultural bacterial evil, not only there is obvious synergistic function, also reduce Pesticide use amount.
Description
Technical field
It is specifically a kind of with Zhongshengmycin and amber glue fertilizer the present invention relates to agricultural bactericidal composition and its application field
Sour copper is the bactericidal composition of active ingredient, applied to preventing and treating agricultural bacterial evil.
Background technology
Zhongshengmycin, English name：Zhongshengmycin, it is N- glycoside antibiotic, by suppressing pathogenetic bacteria egg
The peptide bond generation of white matter, ultimately results in bacterial death.It can not only suppress the growth of hypha,hyphae, suppress the sprouting of spore,
Play a part of preventing and treating fungal disease, the generation of the precursor substance of protective plant protecting agent and lignin in plant can also be stimulated, from
And improve the resistance against diseases of plant, Zhongshengmycin can resisting gram-positive, negative bacteria, mycobacteria, saccharomycete and thread
Fungi, especially to crops pathogenic bacteria such as dish Bacteria erwinia, avenae subsp.citrull, rice leaf spot bacteria, ring rot of apple disease
Bacterium, fusarium graminearum etc..
Tiger glue adipic acid copper, English name：Copper, tiger glue adipic acid copper be succinic acid copper, glutaric acid copper, adipic acid copper it is mixed
Compound, belongs to organic copper fungicide, and tiger glue adipic acid copper mainly passes through copper ion and the potassium ion on cause of disease mycoderm surface, hydrogen ion etc.
Exchange, make protein coagulating on pathogen cell membrane, while part copper ion penetrates into pathogen and combined into the cell with some acid,
The activity of enzyme is influenceed, plays bactericidal action, it is good to cucumber bacterial angular leaf spot, citrus bacterial canker disease and other effects.
Bacterial angular leaf spot is a kind of common bacterial disease of cucumber, and sick blade back portion scab often overflows bacterial ooze, perforated, melon
Bar is aggrieved stink.Soft rot of cabbage is a kind of common bacterial disease of Chinese cabbage, and diseased plant basal part of stem often becomes soft rot, sends evil
It is smelly.The medicine for agriculturally preventing and treating bacterial disease cans be counted on one's fingers, and already leading to germ using same medicine throughout the year develops immunity to drugs.
Different pesticide species compositions are compounded, and are the common methods for preventing and treating agriculture resistance disease.The present inventor is a large amount of
Indoor virulence and field medicine effect test on the basis of, to the compounded formula of Zhongshengmycin and tiger glue adipic acid copper screening carried out depth
Enter research, it is found that Zhongshengmycin and tiger glue adipic acid copper are compounded, there is obvious Synergistic in certain proportion
Effect, and there is outstanding prevention effect to cucumber bacterial angular leaf spot, soft rot of cabbage, after further study, complete this
Invention.
The content of the invention
It is an object of the invention to provide a kind of efficient, low toxicity, inexpensive, quick-acting is good, lasting period length, and crop is pacified
Entirely, environment amenable agricultural bactericidal composition, applied to preventing and treating cucumber bacterial angular leaf spot, soft rot of cabbage.
Technical scheme:A kind of bactericidal composition, effective ingredient are Zhongshengmycin and tiger glue adipic acid copper, Zhongshengmycin and amber glue
The parts by weight ratio of adipic acid copper is 1:10~10:1, the weight of Zhongshengmycin and tiger glue adipic acid weight of copper summation in the composition
Percentage is 4%~97%, and remaining is pesticidal preparations auxiliary element.
The bactericidal composition of the present invention can be processed into suspending agent, moisture dissipates according to well known to a person skilled in the art method
The application forms of the suitable agricultural use such as granula, aqueous emulsion, microemulsion, wettable powder.
The present invention bactericidal composition also containing prepare pesticidal preparations needed for auxiliary element, including emulsifying agent, wetting agent,
One kind in stabilizer, dispersant, thickener, defoamer, antifreezing agent, disintegrant, binding agent, filler, filler, medium etc. or
Several mixing, it is known substance, is the various auxiliary agents commonly used in pesticidal preparations, can be varied from according to different situations, and
It is not particularly limited.
Bactericidal composition described in the invention, it can be provided in the form of finished product preparation, i.e., each material has mixed in composition
Close, the composition of composition can also unit dose form provide, directly mixed using preceding in bucket or tank, be then diluted to needed for it is dense
Degree.
Bactericidal composition described in the invention, for preventing and treating agricultural bacterial evil, the especially bacillary angle spot of cucumber
Disease, soft rot of cabbage.
Bactericidal composition described in the invention, the method for generally use spraying use, and can also use agriculture as needed
That is applied in industry other uses technology.
Bactericidal composition described in the invention has the advantages that：
1st, Zhongshengmycin and tiger glue adipic acid copper compounding have unexpected synergistic function, are used alone and carry than single dose
The high prevention effect to disease；
2nd, Zhongshengmycin and the tiger glue adipic acid copper mechanism of action are different, can delay the generation of disease drug resistance；
3rd, two kinds of active ingredients of Zhongshengmycin and tiger glue adipic acid copper compounding, reduces Pesticide use amount, reduce use into
Originally and the pollution to environment is alleviated.
Embodiment
In order that the objects, technical solutions and advantages of the present invention are more concise, present invention specific examples below
Illustrate, but the present invention is only limitted to absolutely not these examples.As described below is only the preferable embodiment of the present invention, is used only for retouching
State the present invention, it is impossible to be interpreted as limiting the scope of the present invention.It should be pointed out that it is all the spirit and principles in the present invention it
Interior done all any modification, equivalent and improvement etc., should be included in the scope of the protection.Therefore, it is of the invention
The protection domain of patent should be determined by the appended claims.
In these embodiments, unless otherwise indicated, all percentages are weight percentage.
Different types of pesticide active ingredient is compounded, is use cost in current solution agricultural chemicals single dose application process
A kind of and effective means of the problems such as resistance to the action of a drug.After different types of pesticide active ingredient mixture, three kinds of effects are typically exhibited
Type, i.e. summation action, synergistic effect, antagonism.The present inventor a large amount of indoor and outdoors biometrics experiment on the basis of,
It was found that Zhongshengmycin and tiger glue adipic acid copper in the range of certain mixed ratio, have to cucumber bacterial angular leaf spot, soft rot of cabbage
There is significant synergistic effect.
Example of formulations 1：30% Zhongshengmycin tiger glue adipic acid copper suspending agent
Weigh 5% Zhongshengmycin, 25% tiger glue adipic acid copper, 8% sodium lignin sulfonate, 2.5%OP-10 (alkyl phenol polyoxies
Vinethene), 1%CMC (carboxymethyl cellulose), 0.02% organic silicone, 2% glycerine, deionized water complement to 100%.On
It is blended to state raw material, 30% Zhongshengmycin tiger glue adipic acid copper, which is made, after high speed shear disperses 30min, after being ground with skin grinder hangs
Floating agent.
Example of formulations 2：35% Zhongshengmycin tiger glue adipic acid copper microemulsion
Weigh 8% Zhongshengmycin, 27% tiger glue adipic acid copper, 15% phenethyl phenol polyethenoxy ether and agriculture breast 34#, 5% different
Propyl alcohol, 10% dimethylbenzene, 10%N, dinethylformamide, after being sufficiently stirred dissolving, deionized water complements to 100%, continues
Stir to transparent, obtained 35% Zhongshengmycin tiger glue adipic acid copper microemulsion.
Example of formulations 3：20% Zhongshengmycin tiger glue adipic acid aqueous emulsion of copper
Weigh 5% Zhongshengmycin, 15% tiger glue adipic acid copper, 4% phenethyl phenol polyethenoxy ether, 4% alkylbenzenesulfonate,
3%C3-C6Alcohol, 2% glycerine, 0.5% Arabic gum, 0.4% silicone oil, deionized water add to 100% parts by weight.Above-mentioned raw materials pass through
20% Zhongshengmycin tiger glue adipic acid aqueous emulsion of copper is made in mixing, high speed shearing emulsification.
Example of formulations 4：33% Zhongshengmycin tiger glue adipic acid copper wettable powder
Weigh 3% Zhongshengmycin, 30% tiger glue adipic acid copper, 5% pull open powder, 5% naphthalenesulfonate formaldehyde condensation compound, 10% cunning
Stone flour, kaolin add to 100% parts by weight.Above-mentioned raw materials are blended, and 33% Zhongshengmycin amber glue fertilizer is made after air-flow crushing
Sour copper wettable powder.
Example of formulations 5：50% Zhongshengmycin tiger glue adipic acid copper water dispersion granula
Weigh 10% Zhongshengmycin, 40% tiger glue adipic acid copper, 5% mineral oil, 5% NPE, 5% infiltration
The fast T of agent, 2% lauryl sodium sulfate, 5% sodium lignin sulfonate, 4% naphthalene sulfonate, bentonite add to 100% parts by weight.On
State blended raw material, ultra micro air-flow crushing, mixing, the obtained 50% Zhongshengmycin tiger glue adipic acid copper water dispersion granula of granulation.
Assays Example 1：Zhongshengmycin and tiger glue adipic acid copper are to cucumber bacterial angular leaf spot bacterium, Erwinia carotorora
Indoor joint toxicity measuring
Test medicine uses 5% Zhongshengmycin wettable powder and 30% tiger glue adipic acid copper wettable powder.
Reference《Pesticide bioactivity evaluates SOP》, raw survey standard method NY/T1156.16-2008 and NY/T1156.6-
2006.Using turbidity method：By the cucumber bacterial angular leaf spot strain being grown in NA medium slants cultivated in advance, Chinese cabbage
Soft rot strain is diluted to 1 × 10 with sterilized water respectively7The suspension of individual spore/mL concentration, at the NB culture mediums of each drug containing
100 μ L bacterium solutions are inoculated with reason respectively, is placed at 28 DEG C and vibrates (120r/min) culture, often processing sets 4 repetitions.Before starting culture
The turbidity of each processing is determined respectively, when control treatment reaches exponential phase, is determined and is recorded the turbidity of each processing.
According to survey data, the growth inhibition ratio of bacterium is calculated by formula (1), is represented with percentage (%), result of calculation
Retain 2 significant digits.
In formula：
P---- growth inhibition ratios；
A0----blank control turbidity value added；
A1----chemicals treatment turbidity value added.
Synegism evaluation method surveys standard method NY/T1156.6-2006 with reference to raw, according to Sun＆Johnson (1960)
Co-toxicity coefficient method (CTC) evaluate the synergistic effect of pharmacy mix, i.e. CTC≤80 are antagonism, 80<CTC<120 be phase
Add effect, CTC >=120 are synergistic effect.
Percentage composition+medicament of A medicaments in the mixture of mixture theoretical toxicity index (TTI)=medicament A toxicity index × 100
The percentage composition of the mixture Chinese medicine of B toxicity index × 100
All test datas are analyzed using DPS statistical softwares.The growth inhibition of bacterium is calculated according to test data
Rate (%), and using the logarithm value of drug concentration (mg/L) as independent variable x, using the growth inhibition ratio of bacterium as dependent variable y, obtain poison
Power regression equation, coefficient correlation (r), EC50And EC90And its 95% confidence limit.
As can be seen from Table 1 and Table 2, Zhongshengmycin and tiger glue adipic acid copper are 1:10~10:When being compounded in the range of 1, altogether
Malicious coefficient (CTC) is all higher than 120, and synergistic function is shown to cucumber bacterial angular leaf spot bacterium, Erwinia carotorora.Its
In, Zhongshengmycin is with tiger glue adipic acid copper with 1：10 ratio mixture, to cucumber bacterial angular leaf spot bacterium and Erwinia carotorora
Co-toxicity coefficient highest, it is seen that Zhongshengmycin and tiger glue adipic acid copper compounding have reasonability and feasibility.
Table 1, the indoor joint toxicity measuring result to cucumber bacterial angular leaf spot bacterium
Table 2, the indoor joint toxicity measuring result to Erwinia carotorora
Assays Example 2：To the field control effectiveness test of cucumber bacterial angular leaf spot
Bactericidal composition of the present invention is located at Huizhou Chen Jiang towns Huang to cucumber bacterial angular leaf spot test site
Melon patch.In cucumber bacterial angular leaf spot early period of origination dispenser, using spray-on process dispenser, using 5% Zhongshengmycin wettable powder,
30% tiger glue adipic acid copper wettable powder sets 7 chemicals treatments altogether as comparison medicament, experiment, each handles 3 repetitions.Dispenser
It is preceding throughout to manage the cornerwise five points investigation diseased plant number in area, 20 plants of cucumber of every investigation.3 days after dispenser, respectively adjust within 7 days, 14 days
A prevention effect is looked into, records diseased plant number, and calculates prevention effect, result of the test is as shown in table 3.
The result of the test of table 3, Zhongshengmycin and tiger glue adipic acid copper mixture preventing and treating angular leaf spot of cucumber
As can be seen from Table 3 to cucumber bacterial angular leaf spot after Zhongshengmycin and tiger glue adipic acid copper compounding 3d, 7d, 14d
Preventive effect is intended to apparently higher than the Zhongshengmycin wettable powder of the same period 5% and 30% tiger glue adipic acid copper wettable powder, raw in explanation
Rhzomorph and tiger glue adipic acid copper compounding can improve the preventive effect to cucumber bacterial angular leaf spot compared with two kinds of single doses are used alone, together
When medicine after 14d preventive effects still up to more than 80%, illustrate that there is good lasting effect, do not find the compound drug to cucumber during experiment
Produce poisoning.
Assays Example 3：To the field control effectiveness test of soft rot of Chinese cabbage
Bactericidal composition of the present invention is located at Huizhou Chen Jiang towns Chinese cabbage garden to soft rot of cabbage test site.
Soft rot of cabbage early period of origination dispenser, using spray-on process.Can using 5% Zhongshengmycin wettable powder, 30% tiger glue adipic acid copper
WP sets 7 chemicals treatments altogether as comparison medicament, experiment, each handles 3 repetitions.It is diagonal that area is throughout managed before dispenser
Five points investigation diseased plant number of line, 20 plants of Chinese cabbages of every investigation.3 days after dispenser, respectively investigate a prevention effect, note within 7 days, 14 days
Diseased plant number is recorded, and calculates prevention effect, result of the test is as shown in table 4.
The result of the test of table 4, Zhongshengmycin and tiger glue adipic acid copper mixture preventing and treating soft rot of cabbage
As can be seen from Table 4 to the preventive effect of soft rot of Chinese cabbage after Zhongshengmycin and tiger glue adipic acid copper compounding 3d, 7d, 14d
It is intended to, apparently higher than the Zhongshengmycin wettable powder of the same period 5% and 30% tiger glue adipic acid copper wettable powder, illustrate Zhongshengmycin
The preventive effect that can be improved compared with two kinds of single doses are used alone to Chinese cabbage bacterial soft rot, while medicine are compounded with tiger glue adipic acid copper
14d preventive effects illustrate there is good lasting effect, do not find that the compound drug produces to Chinese cabbage during experiment still up to more than 80% afterwards
Poisoning.
In summary, bactericidal composition of the present invention, compared with existing unitary agent, not only make with obvious synergy
With also with good bactericidal effect, lasting period length, to Crop securify, dosage being reduced, be worth above pushing away in agricultural production
Wide application.
Claims (4)
- A kind of 1. bactericidal composition containing Zhongshengmycin and tiger glue adipic acid copper, it is characterised in that：Active ingredient is Zhongshengmycin And tiger glue adipic acid copper, the ratio of weight and number 1 of Zhongshengmycin and tiger glue adipic acid copper:10~10:1, Zhongshengmycin and tiger glue adipic acid copper The percentage by weight of weight summation in the composition is 4%~97%.
- A kind of 2. bactericidal composition containing Zhongshengmycin and tiger glue adipic acid copper according to claim 1, it is characterised in that： The formulation of the bactericidal composition is suspending agent, water dispersible granules, aqueous emulsion, microemulsion or wettable powder.
- 3. a kind of bactericidal composition containing Zhongshengmycin and tiger glue adipic acid copper according to claim 1 is used to prevent and treat agricultural Application in bacterial disease.
- 4. a kind of bactericidal composition containing Zhongshengmycin and tiger glue adipic acid copper according to claim 3 is used to prevent and treat agricultural Application in bacterial disease, it is characterised in that：Described agricultural bacterial evil is that cucumber bacterial angular leaf spot and Chinese cabbage are soft Maize ear rot.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106689202B (en) * | 2015-07-20 | 2019-11-22 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
| CN106614545A (en) * | 2016-12-23 | 2017-05-10 | 江西天祥通用航空股份有限公司 | Oil suspending agent and application thereof in preventing and treating agricultural bacterial diseases |
| CN107347878A (en) * | 2017-07-21 | 2017-11-17 | 江西天祥通用航空股份有限公司 | A kind of suspending agent and its application in bacterial diseases of crops is prevented and treated |
| CN110973143B (en) * | 2019-09-18 | 2022-01-07 | 北京宇悦生物科技有限公司 | Bactericide composition and application thereof |
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| CN1729791A (en) * | 2005-08-25 | 2006-02-08 | 齐军山 | Agricultural sterilizing composition aimed at plant disease |
| CN101536699A (en) * | 2009-04-24 | 2009-09-23 | 深圳诺普信农化股份有限公司 | Bactericidal composition |
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2015
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Patent Citations (3)
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| CN1729791A (en) * | 2005-08-25 | 2006-02-08 | 齐军山 | Agricultural sterilizing composition aimed at plant disease |
| CN101536699A (en) * | 2009-04-24 | 2009-09-23 | 深圳诺普信农化股份有限公司 | Bactericidal composition |
| CN103004879A (en) * | 2013-01-15 | 2013-04-03 | 福建凯立生物制品有限公司 | Bactericide composition aiming at plant bacteria and fungus diseases and application thereof |
Non-Patent Citations (1)
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