CN104274262B - For establishing the indwelling device of heart abnormality passage - Google Patents
For establishing the indwelling device of heart abnormality passage Download PDFInfo
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- CN104274262B CN104274262B CN201410441057.5A CN201410441057A CN104274262B CN 104274262 B CN104274262 B CN 104274262B CN 201410441057 A CN201410441057 A CN 201410441057A CN 104274262 B CN104274262 B CN 104274262B
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Abstract
The invention discloses a kind of indwelling device for being used to establish heart abnormality passage, the indwelling device is the hollow network structure with shape memory that braided wires braiding forms, and includes the left disk body and right disk body and waist of plate-like；Connected between the left disk body and right disk body by waist integral；The left disk body and the elastic construction that right disk body is elastically deformable, the waist are the rigid structure of support；The front end of the left disk body is provided with front port, and the rear portion of the right disk body is provided with rear port, a passage is formed through between the front port, waist inner chamber and rear port；The braided wires end convergence bunchy for being used to weave right disk body at the right disk body rear portion is simultaneously fixed by fixture.The present invention provides a kind of indwelling device that can establish heart abnormality passage, and it is difficult can to solve the problems, such as that pulmonary hypertension model is established.
Description
Technical field
The invention belongs to technical field of medical instruments, is related to a kind of indwelling device, more particularly to a kind of different for establishing heart
The indwelling device in normal open road.
Background technology
Congenital heart disease is a kind of most common heart disease of children, when congenital heart disease refers to embryonic stage or is born i.e.
The defects of existing cardiovascular structure and (or) function, China there are about 150,000 neonates and suffers from congenital heart disease every year, and
The incidence of disease also has increased trend year by year, and congenital heart disease occupy the first place of China's inborn defect at present.Congenital heart disease
Such as not early operation, pulmonary hypertension will occur for 30% patient.Congenital heart disease mechanism is not still fully aware of, wherein
One main reasons is that the model construction difficulty of congenital heart disease, there is no establish stable heart defect mould so far both at home and abroad
The report of type.
Pulmonary hypertension caused by congenital heart disease, is typically due to endocardial or big vascular endothelial has from left to right
Shunt (such as atrial septal defect, ventricular septal defect), cause pulmonary circulation blood flow amount to continue to increase, very high pressure rushes at lung and followed
Ring, make lung arteriolar spasm, produce power type pulmonary hypertension, continuing development can cause pulmonary artery pressure persistently to increase, even
Surmount aortic pressure, lung parteriole intimal thickening and hardening, pulmonary vascular resistance rise, form resistance-type pulmonary hypertension, this
When M-mode echocardiography reduce, then there is bidirectional shunt, or even reversed shunt, the disease for cyanosis and right heart failure clinically occur
Shape, develop into eisenmenger syndrome.Eisenmenger syndrome can not routine operation treatment, can only typically select cardiopulmonary to join
Transplanting is closed, surgery cost is high, and long-term survival of performing the operation, than relatively low, the eisenmenger syndrome of non-row transfer operation treatment is suffered from
Person often dies from heart failure caused by pulmonary hypertension and Secondary cases pulmonary infection.
It is most commonly seen with congenital heart disease in the secondary cause of pulmonary hypertension.The mechanism of pulmonary hypertension is still
Do not illustrate completely, once developing into organic pulmonary hypertension, have a strong impact on health, phase in existing congenital heart disease
Closing the treatment of pulmonary hypertension also simply improves the clinical symptoms of patient, without surgical indication if there is eisenmenger syndrome,
So far also without effective treatment means.
The content of the invention
The technical problem to be solved in the present invention is, for not yet effectively solving lacking for pulmonary hypertension in the prior art
Fall into, there is provided a kind of indwelling device for being used to establish heart abnormality passage.The indwelling device can establish the abnormal passage of heart, can be further
It is difficult to solve the problems, such as that pulmonary hypertension model is established.
The technical solution adopted for the present invention to solve the technical problems is：A kind of indwelling for being used to establish heart abnormality passage
Device, the indwelling device are the hollow network structure with shape memory that forms of braided wires braiding, including the left disk body of plate-like with
Right disk body and waist；Connected between the left disk body and right disk body by waist integral；
The left disk body and the elastic construction that right disk body is elastically deformable, the waist are the rigid structure of support；
The front end of the left disk body is provided with front port, and the rear portion of the right disk body is provided with rear port, the front port, waist
A passage is formed through between inner chamber and rear port；
The braided wires end convergence bunchy for being used to weave right disk body at the right disk body rear portion is simultaneously fixed by fixture.
Preferably, for establishing in the indwelling device of heart abnormality passage, the left disk body, right disk body and waist are braided wires
Weave the integrative-structure formed.
Preferably, for establishing in the indwelling device of heart abnormality passage, the left disk body, right disk body are that cylindrical fabric exists
The radially projecting disk body for forming smooth surface after compression.
Preferably, for establishing in the indwelling device of heart abnormality passage, the left disk body, right disk body, waist are all in
Axis axisymmetricly structure.
Preferably, for establishing in the indwelling device of heart abnormality passage, the front port is located at the disk body center of left disk body,
Or/and the rear port is located at the disk body center of right disk body.
Preferably, for establishing in the indwelling device of heart abnormality passage, the waist is cylindrical shape, oval cylinder or frustum
Tubular, point diameter is more than rear end diameter in the waist of the frustum tubular.
Preferably, for establishing in the indwelling device of heart abnormality passage, the waist is double-deck network structure or Multilayer Network
Shape structure, the left disk body and right disk body are individual layer network structure.
Preferably, for establishing in the indwelling device of heart abnormality passage, the outer wall of the fixture is smooth and without corner angle
Curved surface, the braided wires end is fixed on inside the fixture.
Preferably, for establishing in the indwelling device of heart abnormality passage, the braided wires beam splitting on the fixture is fixed,
The perforation passed through for seal wire is formed between braided wires and fixture.
Preferably, for establishing in the indwelling device of heart abnormality passage, the fixture is correspondingly set at the rear of right disk body
At least two are put, is arranged at intervals between fixture and leaves passage corresponding with rear port.
Indwelling device provided by the present invention for establishing heart abnormality passage, formed using braided wires braiding hollow netted
Structure；After cardiac septum puncture, indwelling device is inserted by the method for intervention and punctured at defect, the wherein left disk body of indwelling device can
To be placed in the left side chambers of the heart, right disk body is placed in the right side chambers of the heart, and because indwelling apparatus has shape memory function, indwelling device is in place
Afterwards, left disk body and right disk body elasticity recover discoid, are clamped on the wall at cardiac puncture, and the front port of indwelling device, waist
Portion inner chamber and rear port form a passage, and waist has anti-blood stream pressure, thus establishes exception between the chambers of the heart of left and right
Passage.According to the diameter for establishing heart abnormality passage, the indwelling device of different waist diameter sizes can be selected, it is therefore, right
There is controllability in the size of abnormal passage.
The present invention forms an abnormal passage between the left and right sides chambers of the heart, and blood is by a left side in the presence of endocardial pressure
Shunt to the right, the change of haemodynamics further results in heart and pulmonary vascular reconstruct, and then establishes the mould of pulmonary hypertension
Type, also laid the foundation for the mechanism research of pulmonary hypertension.Indwelling device is inserted heart by the present invention by the method for intervention,
And the characteristics of carrying out individuation selection according to the size for establishing abnormal passage aperture, farthest to meet abnormal passage part
Anatomical structure, make simple to operate and reliable.
The solution have the advantages that according to the size for establishing heart abnormality channel diameter, different hollow diameters can be selected
Abnormal passage controllability is established in the indwelling device of size, raising.
Brief description of the drawings
Below in conjunction with drawings and Examples, the invention will be further described, in accompanying drawing：
Fig. 1 is the structural representation of the embodiment of the present invention；
Fig. 2 is the top view of the embodiment of the present invention；
Fig. 3 is connection relationship diagram between the fixture of the embodiment of the present invention and braided wires end；
Fig. 4 is that the embodiment of the present invention is arranged on position relationship schematic diagram in conveying device.
Embodiment
In order to which technical characteristic, purpose and the effect of the present invention is more clearly understood, now compares accompanying drawing and describe in detail
The embodiment of the present invention.
The orientation of the present invention is defined according to position of the indwelling device in heart：The disk body for being placed in the left side chambers of the heart is referred to as a left side
Disk body, another disk body for being placed in the right side chambers of the heart are referred to as right disk body, and before being positioned at left side orientation, after right lateral aspect is.
As Figure 1-4, it is a kind of to be used to establishing the indwelling device of heart abnormality passage, the indwelling device be braided wires weave and
Into the hollow network structure with shape memory, including the left disk body 100 of plate-like and right disk body 300 and waist 200；It is described
Connected between left disk body 100 and right disk body 300 by waist 200 integral；The left disk body 100 and right disk body 300 are can bullet
Property deformation elastic construction, the waist 200 for support rigid structure；The front end of the left disk body 100 is provided with front port
101, the rear portion of the right disk body 300 is provided with rear port 301, between the front port 101, the inner chamber of waist 200 and rear port 301
It is formed through a passage；Converge bunchy in the braided wires end 501 for being used to weave right disk body 300 at the rear portion of right disk body 300
And fixed by fixture 500.Described indwelling device is the abnormal blood flow passage for establishing heart, to the direction of blood flow in the chambers of the heart without
Limitation.
As shown in Figure 1, 2, the agent structure of indwelling device is exactly left disk body 100, waist 200 and right disk body 300, wherein left disk
The effect of body 100 and right disk body 300 is to insert heart in indwelling device, and left disk body 100 is located at the left side chambers of the heart, and right disk body 300 is located at
The right side chambers of the heart, left disk body 100 and right disk body 300 are elastic after in place to recover discoid, clamps cardiac septum to fix indwelling device.Waist
Portion 200 is passed through at the defect opened up on heart, the front port 101 of left disk body 100, the inner chamber of waist 200, the rear end of right disk body 300
Mouth 301 penetrates so that hollow structure mutually continues the passage to form abnormal path.
Because indwelling device needs to be implanted in heart by way of conveying device 600 is using intervention, in the mode of intervention
It is to reduce the influence to human body first, therefore, it is necessary to which conveying device 600 is as small as possible, the especially diameter of conveying device 600 is use up
May be small, indwelling device needs to be positioned in conveying device 600, and the diameter of the left disk body 100 of indwelling device and right disk body 300 is more than defeated
The diameter of device 600 is sent, the left disk body 100 and right disk body 300 of such indwelling device need to deform to be adapted to the straight of conveying device 600
Footpath size, after waiting conveying in place, indwelling device is released into conveying device 600, indwelling device self-expanding, left disk body 100 and right disk body 300
The predetermined shape that elasticity is returned to before deformation.
The indwelling device of the present invention is formed using braided wires braiding, and braided wires selection has good biocompatibility and had
The material of shape memory function is made, and can select have wire made of the memory alloy material of shape memory function, example
Such as：Nitinol alloy wire.Memorial alloy is thermally treated to be made required shape, and this is shaped as：In 200 liang of sidebands of waist of tubular
There are the left disk body 100 and right disk body 300 of plate-like.Memorial alloy after heat treatment can reach the super-elasticity and memory performance of needs,
And there is good toughness and hardness, it is unlikely to deform after heart is inserted.The present invention uses indwelling made of memorial alloy in addition
The material of device implantation heart is few, the attachment of no polyester fiber film, reduces rejection of the human body to polyester fiber film, has peace
The characteristics of good perfection.
When weaving indwelling device, the various pieces such as left disk body 100, right disk body 300 and waist 200 can individually be woven, then
Various pieces are woven or are welded together, all parts braiding directly can also be linked into an entirety, this implementation
In example preferably, left disk body 100, right disk body 300 and the waist 200 are the integrative-structure that braided wires braiding forms.It is described to stay
The hollow structure for putting the waist 200 of device is the key for building abnormal passage, and the braided wires for weaving indwelling device run through waist 200 and two
Side panel body, in the indwelling device of integrative-structure, network structure has good overall continuity, has good toughness, security
It is corresponding more preferable.Braided wires size according to be woven indwelling device size, indwelling device requirement performance determine, the waist of the indwelling device
200, for connecting left disk body 100 and right disk body 300 the two hollow structures, and waist 200 itself is formed has certain diameter
The hollow structure of size, when the diameter and all constant braided wires material of the hollow structure of the waist 200, the density of its braided wires
More close then its toughness is bigger, and indwelling device at least 73 one metal wires weave and formed in the present invention.
As shown in Figure 1, 2, the left disk body 100, right disk body 300 are cylindrical fabric radially projecting formation light after compression
The disk body of sliding curved surface.Left disk body 100, right disk body 300 only need to form the disk-like structure of a flat, it is not necessary to their shape
Shape is defined, and the two disk bodies are all without sharp corners, as long as smooth surface.Between left disk body 100, right disk body 300
Compare, the radial dimension size of the two is also not construed as limiting, can be with one big one small, can also left disk body 100, right disk body 300
Radial dimension size is identical.
As shown in Figure 1, 2, indwelling device is from front to back for axially, it is preferable that the left disk body 100, right disk body 300, waist
200 all on indwelling device axis axisymmetricly structure.Left disk body 100, the axially symmetric structure of right disk body 300 can be disk,
Oval plate or other axially symmetric structures.Left disk body 100, right disk body 300 and the axial symmetry of waist 200 are preferred schemes, also
Unsymmetric structure can be used.In the range of admissible diameter, as needed by left disk body 100 and right disk body 300
Shape and position, the shape of the hollow structure of waist 200 carry out any setting, with the foundation suitable for a variety of abnormal passages, enter one
Step improves adaptability and validity that indwelling device establishes heart abnormality path.
The position of the front port 101 and rear port 301 can be located at disk body center, can also eccentric setting, preferably before
Port 101 is located at the disk body center of left disk body 100, or/and the rear port 301 is located at the disk body center of right disk body 300, optimal
Front port 101 and rear port 301 is selected to be all located at the center of disk body.
Waist 200 is installed at the defect of cardiac septum, in order to avoid to bringing injury, the outer wall of waist 200 at defect
Face is smooth, in shape without corner angle.Preferably, the waist 200 is cylindrical shape, oval cylinder or frustum tubular, frustum tubular
To remove the conically shaped at tip.Point diameter is more than rear end diameter in the waist 200 of the frustum tubular, i.e., from left disk body 100
The diameter of 300 waist of disk body 200 is gradually reduced to the right.
Waist 200 is played a supporting role, it is necessary to there is suitable support force, and the waist 200 is preferably double-deck network structure
Or multilayer network structure, and elastic deformation can occur for left disk body 100 and the requirement of right disk body 300, then the left disk body 100 and right disk
Body 300 is individual layer network structure, and left disk body 100 and right disk body 300 can be drawn into tubular structure, to reduce its radial diameter chi
It is very little.Waist 200 is preferably double-deck network structure, it is possible to ensures stability of the waist 200 as support mechanical structure, has one
Fixed support force.The diameter of the hollow structure of waist 200 is that have certain scope, is needed according to the size for establishing abnormal passage
And its situation of surrounding heart tissue is selected, its diameter typically can be in 2mm~10mm.
As shown in Figure 3,4, fixture 500 is provided with indwelling device rear portion, fixture 500 there are multiple effects：First, for inciting somebody to action
Braided wires end 501 is fixed, second, wrapping up the sharp end of braided wires avoids damage to tissue, third, passing through braided wires end 501
Form the connection with conveying device 600.Based on above-mentioned effect, the outer wall of the fixture 500 is smooth and without corner angle curved surface,
The braided wires end 501 is fixed on inside the fixture 500.The mode that braided wires end 501 is fixed can have a variety of, example
Such as：Welding, bonding, compression etc., the present invention is not construed as limiting.The shape of fixture 500 is also not particularly limited, it is only necessary to surface light
Slide without corner angle.
As shown in Figure 3,4, fixture 500 can be spherical, hemispherical, column, irregular shape etc..Fixture 500
Setting quantity it is as needed, due to being connected with conveying device 600, for more stable connection, it is necessary at least two fixtures
500 connect to keep the balance of connection.Preferably, fixture 500 described in the present embodiment is correspondingly arranged at the rear of right disk body 300
At least two, it is arranged at intervals and leaves and 301 corresponding passage of rear port between fixture 500.When fixture 500 sets two
Two fixtures 500 can be oppositely arranged, when setting multiple, fixture 500 is set around axis axial symmetry, and keeps
Space between fixture 500 is corresponding with rear port 301, to form passage.In the axial direction, fixture 500 is apart from right disk body 300
Position it is relevant with the length of braided wires end 501, the length of braided wires end 501, on the one hand can be by this according to being actually needed decision
A little braided wires ends 501 are put together to be fixed by fixture 500 together, on the other hand, with the connecting filament in conveying device 600
601 connections determine.
Braided wires beam splitting on the fixture 500 is fixed, and is formed between braided wires and fixture 500 and is passed through for seal wire
Perforation 502.502 main functions of perforating are：On the one hand, when conveying indwelling device, the connecting filament 601 of conveying device 600 is logical
Cross perforation 502 to be connected and fix with indwelling device, will not free easily, and the connection can be passed through and adjust left disk body 100 and the right side
Angle between disk body 300 so that indwelling device preferably agrees with establishing the surrounding myocardium tissue of passage；On the other hand, it is fixed
The surface of part 500 is smooth, it is possible to reduce the complication such as haemolysis.
Claims (8)
1. a kind of indwelling device for being used to establish heart abnormality passage, it is characterised in that the indwelling device is that braided wires braiding forms
The hollow network structure with shape memory, include the left disk body and right disk body and waist of plate-like；The left disk body and the right side
Connected between disk body by waist integral；
The left disk body and the elastic construction that right disk body is elastically deformable, the waist are the rigid structure of support；
The front end of the left disk body is provided with front port, and the rear portion of the right disk body is provided with rear port, the front port, waist inner chamber
A passage is formed through between rear port；
The braided wires end convergence bunchy for being used to weave right disk body at the right disk body rear portion is simultaneously fixed by fixture；
The left disk body, right disk body are cylindrical fabric radially projecting disk body for forming smooth surface after compression；
The waist is double-deck network structure or multilayer network structure, and the left disk body and right disk body are individual layer network structure.
2. the indwelling device according to claim 1 for being used to establish heart abnormality passage, it is characterised in that the left disk body,
Right disk body and waist are the integrative-structure that braided wires braiding forms.
3. the indwelling device according to claim 2 for being used to establish heart abnormality passage, it is characterised in that the left disk body,
Right disk body, waist are all on axis axisymmetricly structure.
4. the indwelling device according to claim 3 for being used to establish heart abnormality passage, it is characterised in that the front port position
It is located at the disk body center of right disk body in the disk body center of left disk body, or/and the rear port.
5. the indwelling device according to claim 4 for being used to establish heart abnormality passage, it is characterised in that the waist is circle
Tubular, oval cylinder or frustum tubular, point diameter is more than rear end diameter in the waist of the frustum tubular.
6. the indwelling device according to claim 1 for being used to establish heart abnormality passage, it is characterised in that the fixture
Outer wall is smooth and without corner angle curved surface, and the braided wires end is fixed on inside the fixture.
7. the indwelling device according to claim 6 for being used to establish heart abnormality passage, it is characterised in that on the fixture
Braided wires beam splitting fix, the perforation passed through for seal wire is formed between braided wires and fixture.
8. the indwelling device according to claim 6 for being used to establish heart abnormality passage, it is characterised in that the fixture exists
The rear of right disk body is correspondingly arranged at least two, is arranged at intervals between fixture and leaves passage corresponding with rear port.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410441057.5A CN104274262B (en) | 2014-09-01 | 2014-09-01 | For establishing the indwelling device of heart abnormality passage |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410441057.5A CN104274262B (en) | 2014-09-01 | 2014-09-01 | For establishing the indwelling device of heart abnormality passage |
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| Publication Number | Publication Date |
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| CN104274262A CN104274262A (en) | 2015-01-14 |
| CN104274262B true CN104274262B (en) | 2018-01-16 |
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| CN201410441057.5A Active CN104274262B (en) | 2014-09-01 | 2014-09-01 | For establishing the indwelling device of heart abnormality passage |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112220505A (en) * | 2014-09-09 | 2021-01-15 | 奥特鲁泰克控股有限公司 | Flow regulating device in heart |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2524712Y (en) * | 2002-01-08 | 2002-12-11 | 常州市智业医疗仪器研究所 | Cardiac tissue defect reparing rack |
| DE10338702B9 (en) * | 2003-08-22 | 2007-04-26 | Occlutech Gmbh | Occlusioninstrument |
| WO2007115125A2 (en) * | 2006-03-31 | 2007-10-11 | Nmt Medical, Inc. | Deformable flap catch mechanism for occluder device |
| CN101449986B (en) * | 2007-11-28 | 2011-08-31 | 王涛 | Obturator of aorta ductus arteriosus |
| CN201510377U (en) * | 2009-09-18 | 2010-06-23 | 王涛 | Occluder with valve for congenital heart disease |
| CN101940501A (en) * | 2010-09-17 | 2011-01-12 | 蚌埠医学院附属医院 | Method for constructing congenital heart disease with diminutive pulmonary blood animal model |
| CN204072397U (en) * | 2014-09-01 | 2015-01-07 | 王垒 | For setting up the indwelling device of heart abnormality passage |
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Effective date of registration: 20230803 Address after: 430000 Wuhan Donghu New Technology Development Zone, Wuhan, Hubei Province, China Merchants, No. 16 Fozuling Third Road. Building 3, High tech Network Valley, No. 3, 3-3, 3-4, 3-5 (Free Trade Zone, Wuhan Area) Patentee after: WUHAN WEIKE MEDICAL TECHNOLOGY Co.,Ltd. Address before: 710003 No.69 xijuyuan lane, Lianhu District, Xi'an City, Shaanxi Province Patentee before: Wang Lei |