CN104031779A

CN104031779A - Rectoscope washing agent

Info

Publication number: CN104031779A
Application number: CN201410269727.XA
Authority: CN
Inventors: 刘勇
Original assignee: CHUZHOU SMET COMPOUND MATERIALS Co Ltd
Current assignee: CHUZHOU SMET COMPOUND MATERIALS Co Ltd
Priority date: 2014-06-17
Filing date: 2014-06-17
Publication date: 2014-09-10

Abstract

The invention relates to a gastroendoscope cleaning product and in particular relates to a rectoscope washing agent. The rectoscope washing agent comprises the following raw materials: water, 2-hydracrylic acid, methacrolein, (2-hydroxyethyl)diisopropyl methylammonium bromide xanthene-9-carboxylic ester, 2,3,4,5,6-pentahydroxy-2-hexenoic acid-4-lactone, cetyl trimethyl ammonium bromide, bicyclo[2.2.1]heptyl-5-allyl-2-carbonitrile, N-(1-methyl-2-phenoxyethyl)-N-(2-chloroethyl)benzylamine hydrochloride, 3-[4,5-dihydro-1H-imidazole-2-ylmethyl-(4-methylphenyl)amino]phenol. The washing agent has a good and remarkable dirt removal effect, especially has a relatively good sterilizing effect while removing dirt generated in a rectal examination process and especially has a remarkable removal effect on three types of bacteria existent in rectums, so that the cleanness and the safety of a rectoscope are ensured on aspects of dirt removal and sterilization.

Description

Rectoscope washing composition

Technical field

The present invention relates to a kind of digestive endoscopy cleaning supplies, particularly PROCTO washing composition.

background technology

Proctoscopy is to utilize to be about a 20CM straight tube, and end is equipped with a strip of light miniature electronic Kamera, by anus, slowly enters rectum, to check the pathology at rectum position, and as tumour or the disease of bursting, desirable tissue check whenever necessary.Although require defecation before patient, keep emptied rectum, rectoscope still inevitably with spot and bacterium, thereby is necessary it to clean targetedly after checking, to guarantee each hygienic safety using.

Summary of the invention

The object of the present invention is to provide a kind of cleaning capacity strong and with the rectoscope washing composition of biocidal efficacies.

Technical problem of the present invention, is achieved by following technical proposals:

Rectoscope washing composition, special character is to be comprised of the raw material of following weight part proportioning: 72 parts, water, 2 hydroxy propanoic acid 20-25 part, methacrylaldehyde 18-20 part, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters 20-22 part, 2, 3, 4, 5, 6-penta hydroxy group-2-hexenoic acid-4-lactone 15-18 part, cetyl trimethylammonium bromide 10-12 part, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN 4-6 part, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride 8-10 part, 3-[4, 5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol 2-4 part.

Preparation method of the present invention: add deionized water, add while stirring Lactic acid to continue to be stirred to and be uniformly dispersed, be then heated to 40-50 ℃; Slowly add methacrylaldehyde, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters, stir and make it to dissolve; Add 2,3,4,5,6-penta hydroxy group-2-hexenoic acid-4-lactone, cetyl trimethylammonium bromide, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride, 3-[4,5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol, stir; Be cooled to 30-35 ℃, obtain required rectoscope washing composition.

This rectoscope washing composition, utilizes interaction between related chemical constituents, influences each other, and has good greasiness removal effect, particularly when going stain, has good sterilization effect, in going stain and sterilization to guarantee on both side PROCTO clean and safe.

Embodiment

Below provide the specific embodiment of the present invention, be used for the present invention to be further described.In the present invention, if no special instructions, each raw material all be take working substance content as 100%.

In following examples and comparative example, raw material introduction:

Lactic acid CAS accession number is: 50-21-5;

Methacrylaldehyde, CAS accession number is: 78-85-3;

(2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters, CAS accession number is: 50-34-0;

2,3,4,5,6-penta hydroxy group-2-hexenoic acid-4-lactone, CAS accession number is: 50-81-7;

Cetyl trimethylammonium bromide, CAS accession number is: 57-09-0;

Dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN, CAS accession number is: 95-11-4;

N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride, CAS accession number is: 63-92-3;

3-[4,5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol, CAS accession number is: 73-05-2.

Embodiment 1

Weigh: water 72kg, 2 hydroxy propanoic acid 22kg, methacrylaldehyde 18kg, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters 22kg, 2,3,4,5,6-penta hydroxy group-2-hexenoic acid-4-lactone 18kg, cetyl trimethylammonium bromide 10kg, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN 6kg, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride 10kg, 3-[4,5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol 4kg.

The preparation method of this embodiment rectoscope washing composition: add deionized water, add while stirring Lactic acid to continue to be stirred to and be uniformly dispersed, be then heated to 40-50 ℃; Slowly add methacrylaldehyde, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters, stir and make it to dissolve; Add 2,3,4,5,6-penta hydroxy group-2-hexenoic acid-4-lactone, cetyl trimethylammonium bromide, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride, 3-[4,5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol, stir; Be cooled to 30-35 ℃, obtain required rectoscope washing composition.

The present embodiment product performance:

Sterilizing power: intestinal bacteria 99.8%, Salmonellas 99.7%, suis 99.5%.

Embodiment 2

Weigh: water 72kg, 2 hydroxy propanoic acid 20kg, methacrylaldehyde 20kg, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters 21kg, 2,3,4,5,6-penta hydroxy group-2-hexenoic acid-4-lactone 15kg, cetyl trimethylammonium bromide 12kg, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN 4kg, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride 8kg, 3-[4,5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol 3kg.

The preparation method of this embodiment rectoscope washing composition is with embodiment 1.

The present embodiment product performance:

Sterilizing power: intestinal bacteria 99.6%, Salmonellas 99.8%, suis 99.4%.

Embodiment 3

Weigh: water 72kg, 2 hydroxy propanoic acid 25kg, methacrylaldehyde 19kg, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters 20kg, 2,3,4,5,6-penta hydroxy group-2-hexenoic acid-4-lactone 16kg, cetyl trimethylammonium bromide 11kg, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN 5kg, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride 9kg, 3-[4,5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol 2kg.

The present embodiment product performance:

Sterilizing power: intestinal bacteria 99.5%, Salmonellas 99.2%, suis 99.6%.

Comparative example 1

Weigh: water 72kg, 2 hydroxy propanoic acid 22kg, methacrylaldehyde 18kg, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters 22kg, cetyl trimethylammonium bromide 10kg, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN 6kg, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride 10kg.

The preparation method of this comparative example rectoscope washing composition: add deionized water, add while stirring Lactic acid to continue to be stirred to and be uniformly dispersed, be then heated to 40-50 ℃; Slowly add methacrylaldehyde, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters, stir and make it to dissolve; Add cetyl trimethylammonium bromide, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride, stir; Be cooled to 30-35 ℃, obtain required rectoscope washing composition.

This comparative example product performance:

Sterilizing power: intestinal bacteria 82.5%, Salmonellas 86.7%, suis 78.8%.

Comparative example 2

Weigh: water 72kg, 2 hydroxy propanoic acid 22kg, 2,3,4,5,6-penta hydroxy group-2-hexenoic acid-4-lactone 18kg, cetyl trimethylammonium bromide 10kg, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN 6kg, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride 10kg, 3-[4,5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol 4kg.

The preparation method of this comparative example rectoscope washing composition: add deionized water, add while stirring Lactic acid to continue to be stirred to and be uniformly dispersed, be then heated to 40-50 ℃; Slowly add 2,3,4,5,6-penta hydroxy group-2-hexenoic acid-4-lactone, cetyl trimethylammonium bromide, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride, 3-[4,5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol, stir; Be cooled to 30-35 ℃, obtain required rectoscope washing composition.

This comparative example product performance:

Sterilizing power: intestinal bacteria 72.3%, Salmonellas 70.1%, suis 68.5%.

With embodiment 1-3 and comparative example 1-2 gained finished product, carry out detergency test, concrete steps are as follows:

1) preparation of artificial dirt

Mixing oil formula: take butter, lard, vegetables oil mass ratio is 0.5:0.5:1 configuration, and adds the glyceryl monostearate of its total mass 5%, and this is artificial dirt.

Artificial dirt is put on electric furnace and is heated to 220 ℃, stir and keep this temperature 15min, beaker is moved to magnetic stirrer and stir, naturally cool to temperature required standby.The temperature reference of defiling: when room temperature is 20 ℃, need 80 ℃ of oil temperatures; When room temperature is 25 ℃, need 45 ℃ of oil temperatures; When room temperature is lower than 17 ℃ or during higher than 27 ℃, test should not be carried out, and need under temperature adapt circumstance, carry out.Should use the Terg-O-Tometer of attached freezing plant if desired.

2) defile

By clean rectoscope take five put and weigh on frame as one group, with balance, be accurately weighed as W0, the rectoscope after weighing is placed on rack one by one.

When greasy dirt remains in stable temperature, one by one rectoscope is got on to take off from rack, all immerse in greasy dirt and keep 2-3s, slowly take out, after the lower speed of greasy dirt is slack-off, put back to original rack, prepare successively dirty mould bases.After the greasy dirt on rectoscope solidifies, rectoscope is taken off with filter paper or absorbent cotton corner or the unnecessary greasy dirt of side are wiped.Under room temperature, after standing 4h, weighing on frame, with balance accurate weighing, be W1.

3) testing sequence

The rectoscope of known greasy dirt amount is inserted in corresponding wash stand and prepared to wash.

Spotter is switched on power, and wash temperature is set to 32 ℃, and velocity of rotation is set to 150r/min, and washing time is set to 5min.

Take 5.0g sample to be tested in 2500ml hard water, after shaking up, measure respectively 800ml test solution in five washing becks of Terg-O-Tometer, when test solution temperature rises to 32 ℃, rapidly the rectoscope of known weight is put into washing beck accordingly together with wash stand, after putting into washing beck, last rectoscope starts to count soak time, rapidly agitator is installed simultaneously, while soaking 1min, start spotter, start washing, during 5min, machine auto stop, rapidly agitator is taken off, take out wash stand, to wash rear rectoscope is placed on rack one by one, after standing 3h, mould bases being put to corresponding weighing frame weighs as W2.

Result represents

Soil removal efficiency=[(W1-W2)/(W1-W0)] * 100%

?	Soil removal efficiency, %
		Embodiment 1	92.6
Embodiment 2	92.3
		Embodiment 3	91.9
Comparative example 1	79.5
		Comparative example 2	62.4

Claims

1. rectoscope washing composition, it is characterized in that being formed by the raw material of following weight part proportioning: 72 parts, water, 2 hydroxy propanoic acid 20-25 part, methacrylaldehyde 18-20 part, (2-hydroxyethyl) di-isopropyl methyl brometo de amonio cluck ton-9-carboxylicesters 20-22 part, 2, 3, 4, 5, 6-penta hydroxy group-2-hexenoic acid-4-lactone 15-18 part, cetyl trimethylammonium bromide 10-12 part, dicyclo [2.2.1] heptan-5-alkene-2-formonitrile HCN 4-6 part, N-(1-methyl-2-benzene oxygen ethyl)-N-(2-chloroethyl) benzene methanamine hydrochloride 8-10 part, 3-[4, 5-dihydro-1H-imidazoles-2-ylmethyl-(4-aminomethyl phenyl) amino] phenol 2-4 part.