CN102599312B - Oligosaccharide Panax notoginseng sweet tea and preparation method thereof - Google Patents
Oligosaccharide Panax notoginseng sweet tea and preparation method thereof Download PDFInfo
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Abstract
The invention relates to an oligosaccharide Panax notoginseng sweet tea as a functional concentrated tea product and a preparation method of the oligosaccharide Panax notoginseng sweet tea. The oligosaccharide Panax notoginseng sweet tea consists of the following materials by weight: 10-35% of Panax notoginseng leaf/flower extract containing total notoginsenosides, 5-30% of Lithocarpus polystachyus sweet tea extract containing sweetener and sweet tea flavone, 10-30% of Eucommia ulmoides leaf extract and 10-45% of cottonseed oligosaccharide. The preparation method comprises the following steps of combining the active ingredients of the Panax notoginseng leaf/flower extract, the Lithocarpus polystachyus sweet tea extract, and Eucommia ulmoides leaf extract including the total notoginsenosides, the sweet tea flavone and chlorogenic acid to form molecular groups, mixing the obtained mixture and the cottonseed oligosaccharide fully and uniformly, and granulating, so as to obtain raw material of the oligosaccharide Panax notoginseng sweet tea. The Panax notoginseng sweet tea can effectively regulate the endocrine disturbance of human, regulate the alimentation of the gastrointestinal tract and enhance the immunity function, and has dietary therapeutic values in the aspects of prevention and adjuvant therapy for special groups with endocrine disturbance, diabetes, hypertension, hyperlipidemia, gastrointestinal tract inflammation, tumor diseases and the like.
Description
Technical field
According to modern life science and nutrition correlation theory, the present invention is a kind of instant tea that is suitable for the special population practicalities such as endocrine Nutrition and Metabolism functional disturbance (diabetes), high fat of blood, hypertension, intestines and stomach inflammation, atherosclerotic, tumor disease-sweet tea of compound sugar pseudo-ginseng and preparation method thereof.
Background technology
The research of the sweet tea of compound sugar pseudo-ginseng be in the situation that at present endocrine Nutrition and Metabolism functional disturbance (diabetes), high fat of blood, hypertension, gastroenteritis, atherosclerotic, the tumor disease crowd not only increases and the application product that launches is studied.The research and development sweet tea raw material of compound sugar pseudo-ginseng and related preparations product, be intended to, for above-mentioned Disease provides a kind of practicality, the economic sweet taste tea new product of convenience, meet above-mentioned Disease crowd's living needs.
The investigative technique background of the sweet tea of compound sugar pseudo-ginseng is on the basis of feasibility study relevant components material and composition Composition Mechanism, through new formula combination raw material and the related preparations product of experimental study design, its raw material is comprised of sanchi leaf/flower extract, multiple-ear rock Ke sweet tea extract, folium cortex eucommiae concentrated extract, cottonseed compound sugar.
1, sanchi leaf/flower extract
Pseudo-ginseng has another name called pseudo-ginseng, belongs to the Araliaceae herbaceos perennial, adopts and long three petioles of every strain because digging in its after planting three to seven years, and each petiole is given birth to seven blades, therefore named pseudo-ginseng.Its stem, leaf, Hua Junke are used as medicine.Sanchi leaf/flower extract is by sanchi leaf, spends the extract through concentrate drying.Modern pharmacology research shows, the main active ingredient of sanchi leaf/flower extract is arasaponin.Arasaponin (total saponins of Panax notognseng, PNS) is the main effectively active component of araliaceae ginseng plant pseudo-ginseng, contains the various of monomer saponin(e.
(1) function of arasaponin: nearly 3 years " Advance on Pharmacological Activities of arasaponin " research is shown to arasaponin has extensive physiologically active at aspects such as cardio-cerebrovascular, hematological system, immune system, anti-inflammatories through researchers such as Changchun University of Traditional Chinese Medicine's good rain after a long drought, Xu Huibo, the function that confirmation has: (a) improve brain blood circulation: PNS energy expansion of cerebral vascular, reduce cerebral vascular resistance, increase cerebral blood flow (CBF).PNS descends Anaesthetic Rabbits femoral artery mean blood pressure (BMP) and cerebral vascular resistance (CVR), the BMP of anesthetized rat and CVR is descended, and be dose dependent, but not increase cerebral blood flow (CBF), and internal carotid is also had to dilating effect.(b) promote the hematopoietic cell growth: PNS has proliferation function to hematopoietic cell, can induce the synthetic increase of hematopoietic cell GATA 1 and GATA 2 transcriptional regulation proteins, and increase the activity that it is combined with promoter and the enhancer of upstream regulatory region, thereby the expression of regulation and control hematopoietic cell proliferation, differentiation associated gene.(c) antiinflammatory action: PNS has good anti-inflammatory activity to the kinds of experiments inflammatory model.It can suppress to scald the generation of rear macrophage TNF α, suppresses NF KB activity. and intervene NF KB path, thereby reduced the expression of TNF α mRNA; Also can suppress leukocytoplania and albumen that carrageenan induces and ooze out, reduce leukocyte count in irrigating solution, stop MDA content to raise, suppress neutrophil leucocyte and discharge O
2-, increase cAMP content in Neu, thereby reduce O
2The lipid peroxidation injury brought out Deng free radical.(d) on the impact of immunologic function: PNS has the enhancing immunity, SPL increment, the conversion of energy obvious stimulation mouse, promote mouse delayed allergy effect, improve mouse antibodies cellulation number, improve the serum hemolysin of mouse, promote mouse monokaryon-macrophage carbon to clean up effect, the monokaryon of enhancing mouse-peritoneal macrophage phagocytic activity, improve the NK cells in mice activity.
(2) notoginsenoside antitumor action: the yellow clear pine of basis institute of Guangdong Pharmaceutical University, the researchers such as Li Hongzhi, Zhang Yongli study anti-sudden change and the antitumor action of Ginsenoside Rg1 " the anti-sudden change of Ginsenoside Rg1 and antitumor research " purpose, inquire into the drug effect of Ginsenoside Rg1 monomer.Method is observed the antimutagenic effect of Ginsenoside Rg1 with mouse Bone marrow cells micronucleus experiment and testicular chromosome distortion experiment, with S-180 and H-22 transplanted tumor, observe the antitumous effect of Ginsenoside Rg1.Ginsenoside Rg1 all has obvious inhibition to the Testicular Cells chromosome aberration that mouse Bone marrow cells micronucleus occurs and mitomycin brings out of Induced by Cyclophosphamide as a result; S-180 and the growth of H-22 mice transplanted tumor are also had to obvious inhibitory action.The conclusion Ginsenoside Rg1 all has protective effect to the DNA damage of body cell and reproduction cell, and mice transplanted tumor is also had to certain tumor-inhibiting action.
2, Pasania cuspidata sweet tea extract
Pasania cuspidata (lithocarpus polystachyus Rehd), call sweet tea, is the Fagaceae oak plant.Many scientists include sweet ingredient to the Pasania cuspidata Wild sweet tea and are studied, Chinese Academy of Sciences's south China Institute of Zoology in 1992 and Japan are all kindly to be changed into Co., Ltd. and cooperates, the 2 kinds of natural glucin crystallizations that obtain of purifying through multiple chemical are carried out to the molecular structure evaluation, result is that two kinds of crystallizations all contain first phloretin---the dihydrochalcone of same glucoside, claim again the dihydrochalcone glycoside, belong to Flavonoid substances.Agricultural University Of Southwest in 1999 carries out nuclear magnetic resonance spectrometry to isolated sweet taste crystallization in experiment and has confirmed that further this strong sweet taste thing is dihydrochalcone.The sugariness of dihydrochalcone is 150 times of sucrose, and heat is only one of three percentages of sucrose, and without bitter taste, nontoxicity.
(1) sweet tea extract has hypoglycemic, effect for reducing fat: through South China Science & Engineering University's light industry and Foodstuffs Academy Dong Hua Qiang, Ning Zhengxiang etc., its tender leaf of the sweet tea of " the hypoglycemic blood fat effect of Pasania cuspidata flavones phloridzin to diabetic mice " research Pasania cuspidata is contained to abundant flavones phloridzin.This research Pasania cuspidata phloridzin (STPh) of separation and purification, with 4 dosage, fill with and feed the diabetic mice 18d that alloxan is induced, with non-model and model mice tank, feed with amount distilled water and compare, fill with and feed the positive contrast of diabetes pill, then detect its blood sugar (BG), serum triglyceride (TG), T-CHOL (TC), MDA (MDA) level and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activity.Result shows, STPh processes BG, TG, TC and the MDA level that has effectively reduced diabetic mice, and to increasing SOD in serum, the GSH-Px activity also has obvious facilitation, the 70mg/kgbwd of wherein take is optimal dose.This shows that STPh has obvious positive role to diabetes control.
(2) sweet tea extract has hypoglycemic and non-toxic reaction: to " research of Pasania cuspidata extract long term toxicity ", research purpose is observed the Pasania cuspidata extract and is repeated the toxic reaction that gavage produces rat through traditional Chinese medicine research institute of Guangxi autonomous region Zeng Xianbiao, Wei Baowei etc.Method high dose group (2g extract kg-1d-1), middle dosage group (1g extract kg-1d-1), low dose group (0.5g extract kg-1d-1) and blank group, each 50 of rats, gavage the Pasania cuspidata extract, continuous 25 weeks, 2 weeks during respectively at administration mid-term, drug withdrawal and after drug withdrawal, get the part rat and carry out 16 hematological indices, 15 serological biochemical markers inspections, microexamination 29 place's histopathologies change.Each administration group blood one sugar during administration is starkly lower than control group (P0.05) as a result, and during the high dose group drug withdrawal, liver function index is significantly higher than control group (P0.05), and degeneration of liver cells, and all the other each group inspections show no obvious abnormalities.Conclusion Pasania cuspidata extract oral administration has the effect of the rat blood sugar of reduction, outside the visible invertibity hepatotoxicity of long-term, high-dose administration changes, has no significantly other toxic reactions.
The sweet tea of Pasania cuspidata is flat, flavor is sweet, clearing heat and promoting diuresis, tool food, medicine compatibility.Practice among the people confirms, sweet tea relieves heat and thirst, moistening lung, kidney tonifying, the function such as hypotensive and hypoglycemic, and particularly diabetic's long-term drinking is received good blood sugar decreasing effect.It has natural pure, be of high nutritive value, health care is strong, the large advantage of unique flavor four, is a kind of wild rare resources be of great rarity that western developed country is being found.Multiple-ear rock Ke Wild sweet tea reaches more than 80,000 mu (5333 hectares) at the wild area in snowy peak mountain area, produces fresh and tender leaf per year and reaches more than 1600 ton, accounts for 1/5th of national total output.
3, folium cortex eucommiae concentrated extract
The bark of eucommia (Eucommiaulmoides) is Eucommiaceae bark of eucommia platymiscium, is the endemic tree of the residual extinct plants and animal of China's third generation.The bark of eucommia is traditional Chinese medical science traditional Chinese medicine material, and the famous medical scholar's Compendium of Material Medica that Li Shizhen (1518-1593 A.D.) is shown of ancient Chinese is carried " bark of eucommia, can enter the liver kidney tonifying, bowl spares benefit vital essence, hard muscles and bones, strong will, control lumbago due to the kidney deficiency, and clothes, make light of one's life by commiting suicide anti-old for a long time." bark of eucommia is classified the Chinese medicine history of top grade existing more than 2000 year as.The Li Shizhen (1518-1593 A.D.) day bark of eucommia " for a long time clothes make light of one's life by commiting suicide anti-old ", illustrate that the bark of eucommia is ill to cure the disease the effect of anosis health care.
Folium cortex eucommiae is the dry leaf of Eucommiaceae plant bark of eucommia Eucommia ulmoides Oliv..
(1) eucommia leaf extract composition and function: through Jiangxi Prov. Medicine Inst, rely beautiful China, the researchers such as Xu Liying, Rao Hua studies confirm that " folium cortex eucommiae chemical composition and pharmacological research overview ": eucommia leaf extract contains chlorogenic acid, Geniposidic acid, Aucubin, flavonoids isoreactivity composition; Folium cortex eucommiae has immune-enhancing activity, regulates blood pressure, reduces blood sugar, regulates blood fat, antibiotic, antiviral, anti-stress, the pharmacological action such as inhibition tumor cell growth; The chemical composition of folium cortex eucommiae and skin is basically identical, and folium cortex eucommiae and leatherware have equal effect aspect pharmacological effect.
(2) useful effect of eucommia leaf extract on the treatment vascular hypertension: through researchers such as the Tang Zhi of medical college of University Of Nanhua break Peng Juan Jiang Jinlan at the animal experiment study on " impact of extractives of Eucommia ulmoides Leaves on levels of blood pressure in awake rats ", purpose: observe eucommia leaf extract acute and chronic hypotensive effect.Method: measure Conscious Rat arteria caudalis blood pressure with method of indirectly measuring blood pressure: (a) measure the repeatedly blood pressure of gavage eucommia leaf extract of spontaneous hypertensive rat (SHR), observe its Chronic Hypotensive Effect.(b) measure after 1 gavage eucommia ulmoides extracts of renal hypertensive rat 1,2,4,6, the blood pressure of 8h, to observe the extract Acute Hypotensive Effect.Result: (1) continuous 18d gavage eucommia leaf extract 4.2g.kg-1 or 6.3g.kg-1 all obviously reduce the SHR blood pressure.(2) disposable filling eucommia leaf extract 4.2g.kg-1 or 6.3g.kg-1 all obviously reduce the renal hypertensive rat blood pressure.Conclusion: eucommia leaf extract has the effect of obvious reduction acute and chronic blood pressure.
4. cottonseed compound sugar
The main component of cottonseed compound sugar be raffinose, stachyose, disaccharides, polysaccharide wherein content maximum for raffinose, raffinose claims again melitriose, by the oligomeric trisaccharide that galactolipin, glucose and fructose form, molecular formula: C
18H
32O
16, molecular weight: 504, sugariness is 23% left and right of sucrose.
Through " cottonseed compound sugar one raffinose research overview ", set forth, the cottonseed compound sugar in a large number can not be for digesting zymolytic chemical bond because containing, in stomach and small intestine, almost can not digestedly absorb, and it is mainly to embody by the proliferation function to intestinal beneficial bacterium groups such as Bacillus acidi lactici, Bifidobacteriums to the useful physiological function of human body.Bacillus acidi lactici and Bifidobacterium can produce a series of glycosidases in the large intestine enteron aisle, the enzyme of existing cut-out cottonseed compound sugar end glycosidic bond also has the enzyme that is hydrolyzed the interoside key.Take Bifidobacterium, Bacillus acidi lactici as the archenteric flora of advantage optionally to the utilization of fermenting of cottonseed compound sugar, make the speed of growth of Bifidobacterium and Bacillus acidi lactici accelerate, quantity increases, pernicious bacteria is difficult to utilize the cottonseed compound sugar simultaneously, quantity reduces, form this those long healthy gut flora environment that disappear, thereby bring a series of beneficial effect to human body.(1). impel Bifidobacterium propagation, regulating intestinal canal flora.(2). the P H value of regulating intestinal canal, suppress the growth of harmful intestinal tract bacteria, thereby suppressed endotoxin, alleviate burden of liver.(3). promote bowel movement, improve the nutrient absorption rate, prevent constipation.(4). synthetic vitamin increases the needed nutriments of growth of animal such as B family vitamin (B1, B2, B6, folic acid etc.), vitamin K, niacin and amino acid.(5). delay organism aging process, strengthen immunity of organisms.(6). improve the absorptivity of ferrous iron, calcium and vitamin D.(7). produce SCFA, reduce cholesterol, improve lipid-metabolism.
A research of Japan shows, Healthy People absorbs 10g cottonseed compound sugar every day, the intestinal bifidobacteria proportion can rise to 58.2%～80.1% by original 15%, from above function, can find out, the cottonseed compound sugar is a kind of functional oligose with fine health-care effect, is the Bifidobacterium from cottonseed, the super nutritive agent of Bacillus acidi lactici.
The cottonseed compound sugar is a kind of raw produce; raw products with high added value be rich in cottonseed, and 2010 No. 3 literary composition approval cottonseed compound sugar of Ministry of Health of the People's Republic of China is new resource food, and urgently we develop.
How, by the effective combination of above-mentioned raw materials material composition, make it to form, bring into play better function, and impel the absorption of human body utilization, be still and need the technical task that experimental study solves badly.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of instant tea--the sweet tea of compound sugar pseudo-ginseng and preparation method and correlated product production method that is suitable for the special population practicalities such as endocrine Nutrition and Metabolism functional disturbance (diabetes), high fat of blood, hypertension, intestines and stomach inflammation, atherosclerotic, tumor disease.
For solving the problems of the technologies described above, the invention provides the sweet tea raw material of a kind of new type natural sweet tea of compound sugar pseudo-ginseng one by one, its feature is by weight ratio sanchi leaf/flower extract 10%-35%, sweet tea extract 5%-30%, folium cortex eucommiae concentrated extract 10%-30% and cottonseed compound sugar 10%--45% are as constituent.
Described sanchi leaf/flower extract contains the notoginseng total saponin composition more than 20%; Described sweet tea extract contains the sweet tea flavones more than 15%, and described folium cortex eucommiae concentrated extract contains the chlorogenic acid more than 20%.
The described sweet tea of the sweet tea of described compound sugar pseudo-ginseng is natural sweet taste plant Fagaceae oak plant Pasania cuspidata (lithocarpus polystachyus Rehd) Wild sweet tea.
The present invention also provides the preparation method of the sweet tea of a kind of described compound sugar pseudo-ginseng, it is characterized in that comprising the following steps:
Step 1, by described sanchi leaf/flower extract, sweet tea extract, folium cortex eucommiae concentrated extract respectively after low temperature drying dehydration, under normal temperature, gnotobasis condition, by extract dry powder determination of raw material component content, mistake 100 mesh sieves that make, fully mixing, standing, make the sweet tea flavones of notoginseng total saponin, sweet tea extract of sanchi leaf/flower extract, the chlorogenic acid active ingredient in the folium cortex eucommiae concentrated extract be combined into molecule group;
Step 2, the mixture that step 1 will be obtained fully mixes, granulates with cottonseed compound sugar composition again, namely obtains the sweet tea raw material of compound sugar pseudo-ginseng thing.
By the sweet tea raw material of the compound sugar pseudo-ginseng thing made, make granula, capsule, three kinds of formulation products of tablet by required formulation process.
The present invention is on the experiment basis of associated biomolecule composition of raw material, functional character, through demonstration, experimental study and the new special tea product formed.The sweet tea material products of compound sugar pseudo-ginseng is the balance the body endocrinopathy effectively, strengthen the human immunologic function, regulate the enteral nutritional support metabolism, aspect the special populations such as prevention, adjuvant therapy of diabetes, high fat of blood, hypertension, intestines and stomach inflammation, atherosclerotic, tumor disease, have dietary function value.
The specific embodiment
The sweet tea of compound sugar pseudo-ginseng is by weight ratio sanchi leaf/flower extract 10%-35%, sweet tea extract 5%-30%, and folium cortex eucommiae concentrated extract 10%-30% and cottonseed compound sugar 10%--45% are as constituent.Wherein, sanchi leaf/flower extract contains the notoginseng total saponin composition more than 20%; Sweet tea extract contains the sweet tea flavones more than 15%, and the folium cortex eucommiae concentrated extract contains the chlorogenic acid more than 20%.The concrete sweet tea preparation method of compound sugar pseudo-ginseng of implementing is: by described sanchi leaf/flower extract, Pasania cuspidata sweet tea extract, folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration, under normal temperature, gnotobasis condition, by extract dry powder determination of raw material component content, mistake 100 mesh sieves that make, fully mixing, standing, make the active ingredients such as the notoginseng total saponin in its sanchi leaf/flower extract, Pasania cuspidata sweet tea extract, folium cortex eucommiae concentrated extract, sweet tea flavones, chlorogenic acid be combined into molecule group; The mixture obtained is fully mixed, granulates with cottonseed compound sugar composition again, namely obtain the sweet tea raw material of compound sugar pseudo-ginseng thing.By the sweet tea feed particles of compound sugar pseudo-ginseng that this preparation method makes, carry out aseptic process, metering, packing, be sealed to bag, make the granula bagged product.
Below enumerate the specific embodiment of the invention:
Example 1, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 10% sanchi leaf/flower extract, 15% sweet tea extract fully mixes in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 45% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 2, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 25% sanchi leaf/flower extract, 5% sweet tea extract fully mixes in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 40% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 3, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 25% sanchi leaf/flower extract, 20% sweet tea extract fully mixes in the factory formula ratio with 10% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 45% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 4, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 30% sanchi leaf/flower extract, 30% sweet tea extract fully mixes in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 10% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 5, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 25% sanchi leaf/flower extract, 15% sweet tea extract fully mixes in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 30% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 6, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 35% sanchi leaf/flower extract, 15% sweet tea extract fully mixes in the factory formula ratio with 25% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 25% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 7, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 15% sanchi leaf/flower extract, 30% sweet tea extract fully mixes in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 25% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 8, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 35% sanchi leaf/flower extract, 15% sweet tea extract fully mixes in the factory formula ratio with 20% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 30% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 9, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 20% sanchi leaf/flower extract, 10% sweet tea extract fully mixes in the factory formula ratio with 25% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 45% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
Example 10, sanchi leaf/the flower extract that the sweet tea constitutive material of compound sugar pseudo-ginseng is contained to the notoginseng total saponin composition more than 20%, the Pasania cuspidata sweet tea extract that contains the sweet tea flavones more than 15%, contain the folium cortex eucommiae concentrated extract of the chlorogenic acid more than 20% respectively after the low temperature drying dehydration, at normal temperature, under the gnotobasis condition, make the extract made dry powder determination of raw material component content, cross 100 mesh sieves, press production technology quality requirement preparation raw material (1): by 20% sanchi leaf/flower extract, 15% sweet tea extract fully mixes in the factory formula ratio with 30% folium cortex eucommiae concentration extraction, standing, make its notoginseng total saponin, sweet tea flavones, the active ingredients such as chlorogenic acid are combined into molecule group, (2): the mixture of (1) is fully mixed, granulates with 35% cottonseed compound sugar composition more namely obtains the sweet tea raw material of compound sugar pseudo-ginseng granula product.
The sweet tea raw material of the compound sugar pseudo-ginseng granula product be prepared into is carried out to aseptic process, metering, packing, is sealed to bag, makes the granula bagged product.The sweet tea granula of compound sugar pseudo-ginseng, every one 60 bags of box-packed amounts (1.5gx60 bag), net content 90g meter.
The sweet tea of compound sugar pseudo-ginseng of the present invention is special instant tea goods, its formula theory of constitution science, reasonable, the sweet tea Study on Functional of compound sugar pseudo-ginseng active component is extensive, its material products is the balance the body endocrinopathy effectively, strengthen the human immunologic function, regulate the enteral nutritional support metabolism, be applicable to the special populations such as prevention, adjuvant therapy of diabetes, high fat of blood, hypertension, intestines and stomach inflammation, atherosclerotic, tumor disease and use.
The above-described embodiment of take is every day 2 times in the interior sweet tea-drinking method of compound sugar pseudo-ginseng of the present invention, drinks each 1 bag sooner or later; Get before the meal 1 bag of this product, put into the cup warm water of falling 200lm--300lm and drink after to be dissolved.
Claims (4)
1. sweet tea of compound sugar pseudo-ginseng, its feature is by weight ratio sanchi leaf or flower extract 10%-35%, Pasania cuspidata sweet tea extract 5%-30%, and folium cortex eucommiae concentrated extract 10%-30% and cottonseed compound sugar 10%--45% are as constituent.
2. the sweet tea of compound sugar pseudo-ginseng according to claim 1, is characterized in that, described sanchi leaf or flower extract contain the notoginseng total saponin composition more than 20%; Described Pasania cuspidata sweet tea extract contains the sweet tea flavones more than 15%, and described folium cortex eucommiae concentrated extract contains the chlorogenic acid more than 20%.
3. the preparation method of the sweet tea of compound sugar pseudo-ginseng according to claim 1 and 2 is characterized in that comprising the following steps:
Step 1, by described sanchi leaf or flower extract, Pasania cuspidata sweet tea extract, folium cortex eucommiae concentrated extract respectively after the low temperature drying dehydration, under normal temperature, gnotobasis condition, by extract dry powder determination of raw material component content, mistake 100 mesh sieves that make, fully mixing, standing, make the sweet tea flavones of notoginseng total saponin, Pasania cuspidata sweet tea extract of sanchi leaf or flower extract, the chlorogenic acid active ingredient in the folium cortex eucommiae concentrated extract be combined into molecule group;
Step 2, the mixture that step 1 is obtained fully mixes, granulates with cottonseed compound sugar composition again, namely obtains the sweet tea raw material of compound sugar pseudo-ginseng thing.
4. the preparation method of the sweet tea of compound sugar pseudo-ginseng according to claim 3 characterized by further comprising following steps: the sweet tea raw material of the compound sugar pseudo-ginseng thing that will make, by required formulation process, make granula, capsule, three kinds of formulation products of tablet.
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| CN101874875A (en) * | 2010-05-26 | 2010-11-03 | 唐桂德 | Chinese medicinal tea for treating hypertension, hyperlipoidemia and high blood viscosity and preparation method thereof |
| CN102113584A (en) * | 2011-03-15 | 2011-07-06 | 黄选明 | Health preserving tea |
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| CN101874875A (en) * | 2010-05-26 | 2010-11-03 | 唐桂德 | Chinese medicinal tea for treating hypertension, hyperlipoidemia and high blood viscosity and preparation method thereof |
| CN102113584A (en) * | 2011-03-15 | 2011-07-06 | 黄选明 | Health preserving tea |
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