CA2423837A1 - Small volume in vitro analyte sensor and methods - Google Patents
Small volume in vitro analyte sensor and methods Download PDFInfo
- Publication number
- CA2423837A1 CA2423837A1 CA002423837A CA2423837A CA2423837A1 CA 2423837 A1 CA2423837 A1 CA 2423837A1 CA 002423837 A CA002423837 A CA 002423837A CA 2423837 A CA2423837 A CA 2423837A CA 2423837 A1 CA2423837 A1 CA 2423837A1
- Authority
- CA
- Canada
- Prior art keywords
- methods
- small volume
- sensor
- analyte
- charge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012491 analyte Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000000338 in vitro Methods 0.000 title 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 abstract 1
- 238000004082 amperometric method Methods 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000013060 biological fluid Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000003869 coulometry Methods 0.000 abstract 1
- 238000007599 discharging Methods 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000004313 potentiometry Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
A small volume sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector. In one embodiment, the sensor determines the concentration of the analyte by discharging an amount of charge into the sample, determining the time needed to discharge the charge, and determining the current used to electrolyze a portion of the analyte using the amount of charge and the amount of time.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/434,026 US6616819B1 (en) | 1999-11-04 | 1999-11-04 | Small volume in vitro analyte sensor and methods |
| US09/434,026 | 1999-11-04 | ||
| CA002358993A CA2358993C (en) | 1999-11-04 | 2000-10-27 | Small volume in vitro analyte sensor and related methods |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002358993A Division CA2358993C (en) | 1999-11-04 | 2000-10-27 | Small volume in vitro analyte sensor and related methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2423837A1 true CA2423837A1 (en) | 2001-05-10 |
| CA2423837C CA2423837C (en) | 2007-09-11 |
Family
ID=25682753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002423837A Expired - Fee Related CA2423837C (en) | 1999-11-04 | 2000-10-27 | Small volume in vitro analyte sensor and methods |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2423837C (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006023810A1 (en) * | 2004-08-20 | 2006-03-02 | Bayer Healthcare Llc | Contact connector assembly for a sensor-dispensing instrument |
| WO2015106331A1 (en) * | 2014-01-16 | 2015-07-23 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence | Lateral flow assay apparatus and method, and sensor therefor |
| US9835582B2 (en) | 2005-09-30 | 2017-12-05 | Ascensia Diabetes Care Holdings Ag | Devices using gated voltammetry methods |
| US9933385B2 (en) | 2007-12-10 | 2018-04-03 | Ascensia Diabetes Care Holdings Ag | Method of using an electrochemical test sensor |
| US10067082B2 (en) | 2004-02-06 | 2018-09-04 | Ascensia Diabetes Care Holdings Ag | Biosensor for determining an analyte concentration |
| US10190150B2 (en) | 2006-10-24 | 2019-01-29 | Ascensia Diabetes Care Holdings Ag | Determining analyte concentration from variant concentration distribution in measurable species |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3483599A1 (en) | 2005-07-20 | 2019-05-15 | Ascensia Diabetes Care Holdings AG | Methods for measuring the concentration of an analyte in solution and for calibrating the measurement as well as handheld devices therefor |
-
2000
- 2000-10-27 CA CA002423837A patent/CA2423837C/en not_active Expired - Fee Related
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10067082B2 (en) | 2004-02-06 | 2018-09-04 | Ascensia Diabetes Care Holdings Ag | Biosensor for determining an analyte concentration |
| US7416430B2 (en) | 2004-08-20 | 2008-08-26 | Bayer Healthcare Llc | Contact connector assembly for a sensor-dispensing instrument |
| US7575457B2 (en) | 2004-08-20 | 2009-08-18 | Bayer Healthcare Llc | Contact connector assembly for a sensor-dispensing instrument |
| CN101040185B (en) * | 2004-08-20 | 2012-11-14 | 拜尔健康护理有限责任公司 | Contact connector assembly for a sensor-dispensing instrument |
| WO2006023810A1 (en) * | 2004-08-20 | 2006-03-02 | Bayer Healthcare Llc | Contact connector assembly for a sensor-dispensing instrument |
| US10670553B2 (en) | 2005-09-30 | 2020-06-02 | Ascensia Diabetes Care Holdings Ag | Devices using gated voltammetry methods |
| US9835582B2 (en) | 2005-09-30 | 2017-12-05 | Ascensia Diabetes Care Holdings Ag | Devices using gated voltammetry methods |
| US11435312B2 (en) | 2005-09-30 | 2022-09-06 | Ascensia Diabetes Care Holdings Ag | Devices using gated voltammetry methods |
| US10190150B2 (en) | 2006-10-24 | 2019-01-29 | Ascensia Diabetes Care Holdings Ag | Determining analyte concentration from variant concentration distribution in measurable species |
| US11091790B2 (en) | 2006-10-24 | 2021-08-17 | Ascensia Diabetes Care Holdings Ag | Determining analyte concentration from variant concentration distribution in measurable species |
| US9933385B2 (en) | 2007-12-10 | 2018-04-03 | Ascensia Diabetes Care Holdings Ag | Method of using an electrochemical test sensor |
| US10690614B2 (en) | 2007-12-10 | 2020-06-23 | Ascensia Diabetes Care Holdings Ag | Method of using an electrochemical test sensor |
| WO2015106331A1 (en) * | 2014-01-16 | 2015-07-23 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence | Lateral flow assay apparatus and method, and sensor therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2423837C (en) | 2007-09-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20201027 |