CA2243272A1 - Inhibiteurs de farnesyl-proteine transferase - Google Patents

Inhibiteurs de farnesyl-proteine transferase Download PDF

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Publication number
CA2243272A1
CA2243272A1 CA 2243272 CA2243272A CA2243272A1 CA 2243272 A1 CA2243272 A1 CA 2243272A1 CA 2243272 CA2243272 CA 2243272 CA 2243272 A CA2243272 A CA 2243272A CA 2243272 A1 CA2243272 A1 CA 2243272A1
Authority
CA
Canada
Prior art keywords
substituted
alkyl
aryl
unsubstituted
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2243272
Other languages
English (en)
Inventor
Christopher J. Dinsmore
George D. Hartman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9607124.6A external-priority patent/GB9607124D0/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1997/001455 external-priority patent/WO1997027853A1/fr
Publication of CA2243272A1 publication Critical patent/CA2243272A1/fr
Abandoned legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composés qui inhibent la farnésyl-protéine transférase (Ttase) et la farnésylation de la protéine oncogène Ras. La présente invention concerne en outre des compositions chimiothérapeutiques contenant lesdits composés et des procédés permettant d'inhiber la farnésyl-protéine transférase et la farnésylation de la protéine oncogène Ras.
CA 2243272 1996-01-30 1997-01-27 Inhibiteurs de farnesyl-proteine transferase Abandoned CA2243272A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1108196P 1996-01-30 1996-01-30
US60/011,081 1996-01-30
GB9607124.6 1996-04-04
GBGB9607124.6A GB9607124D0 (en) 1996-04-04 1996-04-04 Inhibitors of farnesyl-protein transferase
PCT/US1997/001455 WO1997027853A1 (fr) 1996-01-30 1997-01-27 Inhibiteurs de farnesyl-proteine transferase

Publications (1)

Publication Number Publication Date
CA2243272A1 true CA2243272A1 (fr) 1997-08-07

Family

ID=29424172

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2243272 Abandoned CA2243272A1 (fr) 1996-01-30 1997-01-27 Inhibiteurs de farnesyl-proteine transferase

Country Status (1)

Country Link
CA (1) CA2243272A1 (fr)

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Legal Events

Date Code Title Description
FZDE Dead