CA1023753A - Dihydroxyhexahydrodibenzo (b,d) pyrannes - Google Patents

Dihydroxyhexahydrodibenzo (b,d) pyrannes

Info

Publication number
CA1023753A
CA1023753A CA209,538A CA209538A CA1023753A CA 1023753 A CA1023753 A CA 1023753A CA 209538 A CA209538 A CA 209538A CA 1023753 A CA1023753 A CA 1023753A
Authority
CA
Canada
Prior art keywords
dihydroxyhexahydrodibenzo
pyrans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA209,538A
Other languages
English (en)
Inventor
Robert A. Archer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of CA1023753A publication Critical patent/CA1023753A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
CA209,538A 1973-11-05 1974-09-19 Dihydroxyhexahydrodibenzo (b,d) pyrannes Expired CA1023753A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/413,010 US3968125A (en) 1973-11-05 1973-11-05 Dihydroxyhexahydrodibenzo[b,d]pyrans

Publications (1)

Publication Number Publication Date
CA1023753A true CA1023753A (fr) 1978-01-03

Family

ID=23635420

Family Applications (1)

Application Number Title Priority Date Filing Date
CA209,538A Expired CA1023753A (fr) 1973-11-05 1974-09-19 Dihydroxyhexahydrodibenzo (b,d) pyrannes

Country Status (26)

Country Link
US (1) US3968125A (fr)
JP (1) JPS6033835B2 (fr)
AR (1) AR202318A1 (fr)
AT (1) AT336012B (fr)
BE (1) BE821716A (fr)
BG (1) BG26387A3 (fr)
CA (1) CA1023753A (fr)
CH (1) CH605894A5 (fr)
CS (1) CS193507B2 (fr)
DD (1) DD116230A5 (fr)
DE (1) DE2451934C2 (fr)
DK (1) DK136719B (fr)
ES (1) ES431674A1 (fr)
FR (1) FR2249664B1 (fr)
GB (1) GB1487637A (fr)
HU (1) HU169193B (fr)
IE (1) IE40023B1 (fr)
IL (1) IL45644A (fr)
NL (1) NL7414439A (fr)
PH (1) PH11788A (fr)
PL (2) PL95748B1 (fr)
RO (1) RO71766A (fr)
SE (1) SE415762B (fr)
SU (1) SU524517A3 (fr)
YU (1) YU36515B (fr)
ZA (1) ZA745751B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1522057A (en) * 1975-11-03 1978-08-23 Pfizer 9-hydroxydibenzo(b,d)pyrans and intermediates therefor
US4051152A (en) * 1976-01-07 1977-09-27 Sharps Associates Oxo C-ring benzopyrans
US4087546A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiasthmatic drugs
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4054581A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor
US4209520A (en) * 1977-06-17 1980-06-24 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4133819A (en) * 1977-06-17 1979-01-09 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
US4243674A (en) * 1978-06-12 1981-01-06 Pfizer Inc. 9-Hydroxydibenzo[b,d]pyrans and intermediates therefore
US4454144A (en) * 1982-06-21 1984-06-12 Pfizer Inc. Substituted dibenzo[b,d]pyran analgesics
JPS6299930U (fr) * 1985-12-12 1987-06-25
US8449908B2 (en) * 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
EP1554572B1 (fr) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions et procedes de modulation du transport a travers la barriere hematho-encephalique
US20050101590A1 (en) * 2002-02-19 2005-05-12 Kiyoshi Yasui Antipruritics
CA2789262C (fr) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Systeme pharma-informatique
WO2008036682A2 (fr) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap)
MX2010001242A (es) * 2007-07-30 2010-07-02 Alltranz Inc Profarmacos de canabidiol, composiciones que comprenden profarmacos de canabidiol y metodos para utilizar los mismos.
WO2009099670A2 (fr) * 2008-02-08 2009-08-13 Nektar Therapeutics Al, Corporation Conjugués d'oligomère et de cannabinoïde
US20090247619A1 (en) * 2008-03-06 2009-10-01 University Of Kentucky Cannabinoid-Containing Compositions and Methods for Their Use
EP2398500B1 (fr) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Sustème d'administration de médicament à base de glutathionne
US8445002B2 (en) 2009-05-06 2013-05-21 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US20200197357A1 (en) 2017-07-20 2020-06-25 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions and methods of lipophilic drugs
EP3681474A1 (fr) 2017-09-11 2020-07-22 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Compositions et procédés pour l'administration nasale de médicaments en direction du cerveau et en vue d'un effet systémique
US20200345656A1 (en) 2017-11-29 2020-11-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Cannabinoids compositions and methods
EP3873436A1 (fr) 2018-11-04 2021-09-08 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Compositions contenant des cannabinoïdes administrables par voie orale et procédés

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507885A (en) * 1966-03-25 1970-04-21 Hoffmann La Roche 3-alkyl-6h-dibenzo(b,d)pyrans
US3636058A (en) * 1966-03-25 1972-01-18 Hoffmann La Roche 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones
CH558792A (de) * 1971-10-14 1975-02-14 Petrzilka Theodor Verfahren zur herstellung von tetrahydrodibenzopyranen.

Also Published As

Publication number Publication date
FR2249664A1 (fr) 1975-05-30
PH11788A (en) 1978-07-05
JPS5071678A (fr) 1975-06-13
BE821716A (fr) 1975-04-30
DE2451934A1 (de) 1975-05-07
ES431674A1 (es) 1976-11-16
GB1487637A (en) 1977-10-05
DK136719C (fr) 1978-04-24
ATA886374A (de) 1976-08-15
DK573274A (fr) 1975-07-07
CH605894A5 (fr) 1978-10-13
PL93908B1 (fr) 1977-07-30
AU7321274A (en) 1976-03-18
DD116230A5 (fr) 1975-11-12
SE415762B (sv) 1980-10-27
IL45644A (en) 1978-03-10
FR2249664B1 (fr) 1978-03-24
DE2451934C2 (de) 1983-10-06
ZA745751B (en) 1976-04-28
RO71766A (fr) 1982-12-06
BG26387A3 (bg) 1979-03-15
IL45644A0 (en) 1974-11-29
SU524517A3 (ru) 1976-08-05
AT336012B (de) 1977-04-12
NL7414439A (nl) 1975-05-07
HU169193B (fr) 1976-10-28
IE40023L (en) 1975-05-05
DK136719B (da) 1977-11-14
JPS6033835B2 (ja) 1985-08-05
SE7413833L (fr) 1975-05-06
PL95748B1 (pl) 1977-11-30
IE40023B1 (en) 1979-02-28
YU36515B (en) 1984-02-29
YU265874A (en) 1982-02-25
US3968125A (en) 1976-07-06
AR202318A1 (es) 1975-05-30
CS193507B2 (en) 1979-10-31

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