BRPI0923500A2 - uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit. - Google Patents

uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit.

Info

Publication number
BRPI0923500A2
BRPI0923500A2 BRPI0923500-0A BRPI0923500A BRPI0923500A2 BR PI0923500 A2 BRPI0923500 A2 BR PI0923500A2 BR PI0923500 A BRPI0923500 A BR PI0923500A BR PI0923500 A2 BRPI0923500 A2 BR PI0923500A2
Authority
BR
Brazil
Prior art keywords
modulator
kit
composition
receptor agonist
pharmaceutical use
Prior art date
Application number
BRPI0923500-0A
Other languages
English (en)
Inventor
Schmouder Robert
Dumortier Thomas
David Olivier
Looby Michael
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41667217&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0923500(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0923500A2 publication Critical patent/BRPI0923500A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0923500-0A 2008-12-22 2009-12-21 uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit. BRPI0923500A2 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US13967208P 2008-12-22 2008-12-22
US61/139,672 2008-12-22
US21853009P 2009-06-19 2009-06-19
US61/218,530 2009-06-19
US24671509P 2009-09-29 2009-09-29
US61/246,715 2009-09-29
PCT/US2009/068888 WO2010075239A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist

Publications (1)

Publication Number Publication Date
BRPI0923500A2 true BRPI0923500A2 (pt) 2018-05-29

Family

ID=41667217

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923500-0A BRPI0923500A2 (pt) 2008-12-22 2009-12-21 uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit.

Country Status (41)

Country Link
US (11) US20100160259A1 (pt)
EP (7) EP3677260A1 (pt)
JP (7) JP2012513401A (pt)
KR (1) KR101347919B1 (pt)
CN (1) CN102264359A (pt)
AR (1) AR074826A1 (pt)
AU (1) AU2009330176C9 (pt)
BR (1) BRPI0923500A2 (pt)
CA (1) CA2747802C (pt)
CL (2) CL2011001529A1 (pt)
CO (1) CO6390117A2 (pt)
CR (1) CR20110274A (pt)
CU (1) CU20110136A7 (pt)
CY (4) CY1116990T1 (pt)
DK (3) DK2379067T3 (pt)
EA (1) EA201100978A1 (pt)
EC (1) ECSP11011222A (pt)
ES (3) ES2810823T3 (pt)
FR (1) FR20C1060I1 (pt)
HN (1) HN2011001759A (pt)
HR (3) HRP20151190T1 (pt)
HU (4) HUE026869T2 (pt)
IL (3) IL213170A0 (pt)
LT (3) LT3409274T (pt)
LU (1) LUC00183I2 (pt)
MA (1) MA32981B1 (pt)
ME (2) ME03594B (pt)
MX (2) MX2011006623A (pt)
NO (1) NO2020038I1 (pt)
NZ (1) NZ593065A (pt)
PE (1) PE20120337A1 (pt)
PL (3) PL2379067T3 (pt)
PT (3) PT3409274T (pt)
RS (2) RS60666B1 (pt)
SG (1) SG171404A1 (pt)
SI (3) SI3453387T1 (pt)
TN (1) TN2011000272A1 (pt)
TW (1) TW201028143A (pt)
UY (1) UY32352A (pt)
WO (1) WO2010075239A1 (pt)
ZA (2) ZA201103863B (pt)

Families Citing this family (28)

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PT2278960T (pt) * 2008-03-17 2017-03-09 Actelion Pharmaceuticals Ltd Regime de dosagem para um agonista seletivo do recetor s1p1
RS60666B1 (sr) 2008-12-22 2020-09-30 Novartis Ag Režim doziranja agonista s1p receptora
EP2482810A2 (en) 2009-09-29 2012-08-08 Novartis AG Dosage regimen of an s1p receptor modulator
US20110124605A1 (en) * 2009-11-20 2011-05-26 Shreeram Aradhye Use of an S1P Receptor Agonist
CA2786994C (en) 2010-01-27 2018-01-16 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
CN102917698A (zh) * 2010-05-06 2013-02-06 诺瓦提斯公司 二芳基硫醚衍生物的给药方案
EP2455080A1 (en) * 2010-11-23 2012-05-23 Almirall, S.A. S1P1 receptor agonists for use in the treatment of multiple sclerosis
FR2968556B1 (fr) 2010-12-13 2013-12-27 Centre Nat Rech Scient Inhibiteurs des infections a vih et leurs utilisations
MX371290B (es) 2011-01-07 2020-01-24 Novartis Ag Formulaciones inmunosupresoras.
DK2675893T3 (en) 2011-02-18 2019-04-15 Scripps Research Inst Directed differentiation of oligodendrocyte precursor cells into a myelinating cell fate
AR085749A1 (es) 2011-04-01 2013-10-23 Novartis Ag Formulaciones
US9592268B2 (en) 2011-05-23 2017-03-14 Cornell University Endothelium protective materials and methods of use
TW201320994A (zh) 2011-10-11 2013-06-01 Novartis Ag 投藥療程
CA2895172C (en) 2012-08-17 2020-08-18 Actelion Pharmaceuticals Ltd Process for the preparation of|(2z,5z)-5-(3-chloro-4-((r)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3-|(o-tolyl)thiazolidin-4-one and intermediate used in said process
CA2904055A1 (en) * 2013-03-06 2014-09-12 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure
EP3054933A4 (en) 2013-10-11 2017-03-15 Teikoku Pharma USA, Inc. Topical sphingosine-1-phosphate receptor agonist formulations and methods of using the same
US10675254B2 (en) 2013-10-11 2020-06-09 Teikoku Seiyaku Co., Ltd. Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same
EP3129020A1 (en) * 2014-04-10 2017-02-15 Novartis AG S1p modulator immediate release dosage regimen
HRP20220359T8 (hr) 2014-12-11 2022-05-27 Actelion Pharmaceuticals Ltd Režim doziranja ponesimoda, selektivnog agonista receptora s1p1
KR20230151072A (ko) 2015-01-06 2023-10-31 아레나 파마슈티칼스, 인크. S1p1 수용체와 관련된 상태의 치료 방법
US20180042895A1 (en) 2015-02-26 2018-02-15 Novartis Ag Treatment of autoimmune disease in a patient receiving additionally a beta-blocker
ES2929526T3 (es) 2015-06-22 2022-11-29 Arena Pharm Inc Sal cristalina de L-arginina del ácido (R)-2-(7-(4-ciclopentil-3-(trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclo-penta[b]indol-3-il)acético para su uso en trastornos asociados al receptor S1P1
US11478448B2 (en) 2017-02-16 2022-10-25 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
CA3053418A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
MX2022005014A (es) 2019-10-31 2022-05-16 Idorsia Pharmaceuticals Ltd Combinacion de un antagonista de cxcr7 con un modulador del receptor s1p1.
US11135197B2 (en) 2020-02-07 2021-10-05 Argentum Pharmaceuticals Llc Dosage regimen of an S1P receptor modulator
WO2021158848A1 (en) * 2020-02-07 2021-08-12 Argentum Pharmaceuticals Llc Dosage regimen of an s1p receptor agonist
CN113332435B (zh) * 2021-06-18 2022-10-18 广州中医药大学(广州中医药研究院) 鞘氨醇-1-磷酸4受体激动剂及其与真武汤联合在制备治疗慢性肾小球肾炎药物中的应用

Family Cites Families (13)

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KR0155015B1 (ko) 1992-10-21 1998-12-01 고우야 마사시 2-아미노-1,3-프로판디올 화합물 및 면역 억제제
AU2001285331B2 (en) 2000-08-31 2006-04-06 Merck & Co., Inc. Phosphate derivatives as immunoregulatory agents
EP1944026B1 (en) 2002-05-16 2013-06-26 Novartis AG Use of EDG receptor binding agents in cancer
WO2005025553A2 (en) * 2003-09-12 2005-03-24 Neuronova Ab Treatment of disorders of nervous systemsystem with fty720
US20060002999A1 (en) * 2004-06-17 2006-01-05 Forest Laboratories, Inc. Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane
JP2008521827A (ja) * 2004-11-29 2008-06-26 ノバルティス アクチエンゲゼルシャフト Ｓ１ｐ受容体アゴニストの投与レジメン
EP1688141A1 (en) * 2005-01-31 2006-08-09 elbion AG The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome
US10080481B2 (en) * 2005-02-10 2018-09-25 G.I. View Ltd. Advancement techniques for gastrointestinal tool with guiding element
RU2010118457A (ru) * 2007-10-12 2011-11-20 Новартис АГ (CH) Композиции, содержащие модуляторы рецептора сфингозин-1-фосфата (sip)
PT2278960T (pt) * 2008-03-17 2017-03-09 Actelion Pharmaceuticals Ltd Regime de dosagem para um agonista seletivo do recetor s1p1
BRPI0914139A2 (pt) * 2008-06-20 2015-10-20 Novartis Ag composições pediátricas para o tratamento de esclerose múltipla
PL2379069T3 (pl) 2008-12-22 2015-08-31 Novartis Ag Schemat dawkowania agonisty receptora S1P
RS60666B1 (sr) 2008-12-22 2020-09-30 Novartis Ag Režim doziranja agonista s1p receptora

Also Published As

Publication number Publication date
SG171404A1 (en) 2011-07-28
KR101347919B1 (ko) 2014-01-07
ES2552823T3 (es) 2015-12-02
AU2009330176C9 (en) 2017-01-05
EP3453387A1 (en) 2019-03-13
CN102264359A (zh) 2011-11-30
WO2010075239A1 (en) 2010-07-01
ES2760607T3 (es) 2020-05-14
EP3453387B1 (en) 2020-06-03
DK2379067T3 (en) 2015-12-07
SI3453387T1 (sl) 2020-10-30
US20170189353A1 (en) 2017-07-06
US20140148415A1 (en) 2014-05-29
TN2011000272A1 (en) 2012-12-17
LTPA2020005I1 (lt) 2020-12-10
MX2021010759A (es) 2022-07-19
TW201028143A (en) 2010-08-01
JP2024129030A (ja) 2024-09-26
RS59857B1 (sr) 2020-02-28
PL3453387T3 (pl) 2020-11-02
AU2009330176A1 (en) 2011-07-07
HN2011001759A (es) 2013-11-26
US20200330407A1 (en) 2020-10-22
LT3409274T (lt) 2020-02-10
US20220142949A1 (en) 2022-05-12
DK3453387T3 (da) 2020-08-10
SI2379067T1 (sl) 2016-01-29
CY1116990T1 (el) 2017-04-05
LUC00183I2 (pt) 2024-07-01
EP2907511A1 (en) 2015-08-19
PL3409274T3 (pl) 2020-06-01
EP2379067B1 (en) 2015-09-02
JP2014144970A (ja) 2014-08-14
RS60666B1 (sr) 2020-09-30
UY32352A (es) 2010-07-30
AR074826A1 (es) 2011-02-16
CL2013001558A1 (es) 2013-10-25
FR20C1060I1 (fr) 2020-12-25
US20160263061A1 (en) 2016-09-15
PE20120337A1 (es) 2012-04-24
HRP20201167T1 (hr) 2020-12-11
HUE052048T2 (hu) 2021-04-28
SI3409274T1 (sl) 2020-03-31
PL2379067T3 (pl) 2016-02-29
ZA201103863B (en) 2012-10-31
AU2009330176C1 (en) 2016-12-08
JP2017141238A (ja) 2017-08-17
HUE026869T2 (en) 2016-08-29
IL274756A (en) 2020-07-30
LT3453387T (lt) 2020-08-25
JP2019167360A (ja) 2019-10-03
IL278914A (en) 2021-01-31
HUE048717T2 (hu) 2020-08-28
KR20110096175A (ko) 2011-08-29
HUS2000046I1 (hu) 2020-12-28
ECSP11011222A (es) 2011-08-31
CA2747802C (en) 2021-02-09
EP4098256A1 (en) 2022-12-07
CO6390117A2 (es) 2012-02-29
EP3120844A1 (en) 2017-01-25
JP7329965B2 (ja) 2023-08-21
MX2011006623A (es) 2011-07-12
CY1123255T1 (el) 2021-10-29
ME03802B (me) 2021-04-20
AU2009330176B2 (en) 2014-03-06
HRP20192175T1 (hr) 2020-03-20
CY1122812T1 (el) 2021-05-05
EP3677260A1 (en) 2020-07-08
JP2012513401A (ja) 2012-06-14
EP2379067A1 (en) 2011-10-26
PT3409274T (pt) 2019-12-17
EP3409274A1 (en) 2018-12-05
US20190091180A1 (en) 2019-03-28
HUE048717T4 (hu) 2022-02-28
ME03594B (me) 2020-07-20
CL2011001529A1 (es) 2012-02-24
US20140066657A1 (en) 2014-03-06
JP2022103194A (ja) 2022-07-07
MA32981B1 (fr) 2012-01-02
CY2020036I2 (el) 2021-06-25
NO2020038I1 (no) 2020-11-18
DK3409274T3 (da) 2019-12-16
US20100160259A1 (en) 2010-06-24
US20160081949A1 (en) 2016-03-24
HRP20151190T1 (hr) 2016-01-01
IL213170A0 (en) 2011-07-31
JP2016135752A (ja) 2016-07-28
CR20110274A (es) 2011-07-19
EP3409274B1 (en) 2019-11-20
CU20110136A7 (es) 2012-01-31
US20180289638A1 (en) 2018-10-11
PT3453387T (pt) 2020-08-11
CY2020036I1 (el) 2021-03-12
CA2747802A1 (en) 2010-07-01
US20110257133A1 (en) 2011-10-20
NZ593065A (en) 2012-11-30
ES2810823T3 (es) 2021-03-09
EA201100978A1 (ru) 2012-01-30
PT2379067E (pt) 2015-12-23
ZA201205942B (en) 2013-03-27

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Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]