BRPI0817775A2 - Métodos de tratar distúrbios urogenitais-neurológicos usando toxinas clostridiais modificadas - Google Patents
Métodos de tratar distúrbios urogenitais-neurológicos usando toxinas clostridiais modificadasInfo
- Publication number
- BRPI0817775A2 BRPI0817775A2 BRPI0817775A BRPI0817775A2 BR PI0817775 A2 BRPI0817775 A2 BR PI0817775A2 BR PI0817775 A BRPI0817775 A BR PI0817775A BR PI0817775 A2 BRPI0817775 A2 BR PI0817775A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- neurological disorders
- modified clostridial
- clostridial toxins
- treating urogenital
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98202107P | 2007-10-23 | 2007-10-23 | |
US7622808P | 2008-06-27 | 2008-06-27 | |
PCT/US2008/080571 WO2009055351A1 (en) | 2007-10-23 | 2008-10-21 | Methods of treating urogenital-neurological disorders using modified clostridial toxins |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0817775A2 true BRPI0817775A2 (pt) | 2015-03-24 |
Family
ID=40220236
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0817775 BRPI0817775A2 (pt) | 2007-10-23 | 2008-10-21 | Métodos de tratar distúrbios urogenitais-neurológicos usando toxinas clostridiais modificadas |
Country Status (14)
Country | Link |
---|---|
US (1) | US9370548B2 (pt) |
EP (1) | EP2211890A1 (pt) |
JP (1) | JP2011514308A (pt) |
KR (1) | KR20100087019A (pt) |
CN (1) | CN101918021A (pt) |
AU (1) | AU2008316989A1 (pt) |
BR (1) | BRPI0817775A2 (pt) |
CA (1) | CA2703370A1 (pt) |
IL (1) | IL205279A0 (pt) |
MX (1) | MX2010004502A (pt) |
NZ (1) | NZ585108A (pt) |
RU (2) | RU2491086C2 (pt) |
SG (1) | SG185338A1 (pt) |
WO (1) | WO2009055351A1 (pt) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7811584B2 (en) * | 2004-06-30 | 2010-10-12 | Allergan, Inc. | Multivalent clostridial toxins |
US8778634B2 (en) | 2004-12-01 | 2014-07-15 | Syntaxin, Ltd. | Non-cytotoxic protein conjugates |
US8399400B2 (en) | 2004-12-01 | 2013-03-19 | Syntaxin, Ltd. | Fusion proteins |
GB0426394D0 (en) * | 2004-12-01 | 2005-01-05 | Health Prot Agency | Fusion proteins |
US8603779B2 (en) | 2004-12-01 | 2013-12-10 | Syntaxin, Ltd. | Non-cytotoxic protein conjugates |
US8512984B2 (en) | 2004-12-01 | 2013-08-20 | Syntaxin, Ltd. | Non-cytotoxic protein conjugates |
GB0610867D0 (en) | 2006-06-01 | 2006-07-12 | Syntaxin Ltd | Treatment of pain |
EP2211890A1 (en) | 2007-10-23 | 2010-08-04 | Allergan, Inc. | Methods of treating urogenital-neurological disorders using modified clostridial toxins |
US20100303757A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Chronic Neurogenic Inflammation Using Interleukin Retargeted Endopepidases |
US20100303789A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Chronic Neurogenic Inflammation Using Neurotrophin Retargeted Endopepidases |
US20100303791A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Chronic Neurogenic Inflammation Using Glucagon Like Hormone Retargeted Endopepidases |
US20100303794A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Urogenital-Neurological Disorders Using Glucagon Like Hormone Retargeted Endopepidases |
US8198229B2 (en) | 2009-05-29 | 2012-06-12 | Allergan, Inc. | Methods of treating urogenital-neurological disorders using galanin retargeted endopepidases |
US20100303783A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Urogenital-Neurological Disorders Using Tachykinin Retargeted Endopepidases |
US20100303788A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Chronic Neurogenic Inflammation Using Galanin Retargeted Endopepidases |
US20100303756A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Urogenital-Neurological Disorders Using Interleukin Retargeted Endopepidases |
US20100303798A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Urogenital-Neurological Disorders Using Neurotrophin Retargeted Endopepidases |
US8147848B2 (en) | 2009-08-26 | 2012-04-03 | Allergan, Inc. | Method for treating premature ejaculation with a botulinum neurotoxin |
BR112012029666A2 (pt) | 2010-05-20 | 2020-10-06 | Allergan, Inc. | toxinas clostridiais degradáveis |
US20120207704A1 (en) * | 2011-02-14 | 2012-08-16 | Allergan, Inc. | Inhibiting Aberrant Blood Vessel Formation Using Growth Factor Retargeted Endopeptidases |
WO2012112432A1 (en) * | 2011-02-14 | 2012-08-23 | Allergan, Inc. | Methods of inhibiting aberrant blood vessel formation using opioid retargeted endopeptidases |
US20120207742A1 (en) * | 2011-02-14 | 2012-08-16 | Allergan, Inc. | Treatments Using PSMA Ligand Endopeptidases |
WO2012112434A1 (en) * | 2011-02-14 | 2012-08-23 | Allergan, Inc. | Inhibiting aberrant blood vessel formation using retargeted endopeptidases |
US20120251518A1 (en) * | 2011-03-29 | 2012-10-04 | Allergan, Inc. | Endopeptidase Treatment of Sexual Dysfunction Disorders |
US9144600B2 (en) | 2011-07-14 | 2015-09-29 | Allergan, Inc. | Methods for treatment of incontinence associated with sexual activity |
US20140056870A1 (en) | 2012-08-27 | 2014-02-27 | Allergan, Inc. | Fusion proteins |
CN111454931A (zh) | 2012-11-21 | 2020-07-28 | 益普生生物创新有限公司 | 用于制备经蛋白水解处理的多肽的方法 |
GB201312317D0 (en) * | 2013-07-09 | 2013-08-21 | Syntaxin Ltd | Cationic neurotoxins |
JP7100020B2 (ja) * | 2016-08-24 | 2022-07-12 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 操作されたボツリヌス神経毒素 |
US20210259865A1 (en) * | 2020-02-25 | 2021-08-26 | Gyrus Acmi, Inc. D/B/A Olympus Surgical Technologies America | Devices and methods to treat and prevent diverticulitis |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
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US4932936A (en) * | 1988-01-29 | 1990-06-12 | Regents Of The University Of Minnesota | Method and device for pharmacological control of spasticity |
US5401243A (en) * | 1990-08-21 | 1995-03-28 | Associated Synapse Biologics | Controlled administration of chemodenervating pharmaceuticals |
US5437291A (en) * | 1993-08-26 | 1995-08-01 | Univ Johns Hopkins | Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction |
US5766605A (en) * | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
US5670484A (en) * | 1994-05-09 | 1997-09-23 | Binder; William J. | Method for treatment of skin lesions associated with cutaneous cell-proliferative disorders |
US6146886A (en) | 1994-08-19 | 2000-11-14 | Ribozyme Pharmaceuticals, Inc. | RNA polymerase III-based expression of therapeutic RNAs |
GB9508204D0 (en) * | 1995-04-21 | 1995-06-07 | Speywood Lab Ltd | A novel agent able to modify peripheral afferent function |
US5861431A (en) * | 1995-06-07 | 1999-01-19 | Iotek, Inc. | Incontinence treatment |
GB9617671D0 (en) * | 1996-08-23 | 1996-10-02 | Microbiological Res Authority | Recombinant toxin fragments |
US7192596B2 (en) * | 1996-08-23 | 2007-03-20 | The Health Protection Agency Ipsen Limited | Recombinant toxin fragments |
US5939070A (en) * | 1996-10-28 | 1999-08-17 | Wisconsin Alumni Research Foundation | Hybrid botulinal neurotoxins |
US7470431B2 (en) * | 1997-07-15 | 2008-12-30 | The Regents Of The University Of Colorado | Use of neurotoxin therapy for treatment of urological-neurological disorders associated with prostate cancer |
US7449192B2 (en) * | 1997-07-15 | 2008-11-11 | The Regents Of The University Of Colorado | Use of neurotoxin therapy for treatment of urologic and related disorders related to neurogenic bladder dysfunction |
CN1321683C (zh) | 1997-07-15 | 2007-06-20 | 科罗拉多大学董事会 | 神经毒素疗法在泌尿系及相关疾病治疗中的应用 |
US6063768A (en) * | 1997-09-04 | 2000-05-16 | First; Eric R. | Application of botulinum toxin to the management of neurogenic inflammatory disorders |
GB9721189D0 (en) * | 1997-10-08 | 1997-12-03 | Speywood Lab The Limited | Analgesic conjugates |
ES2277854T5 (es) * | 1999-08-25 | 2011-02-04 | Allergan, Inc. | Neurotoxinas recombinantes activables. |
US20030180289A1 (en) * | 1999-09-23 | 2003-09-25 | Foster Keith Alan | Inhibition of secretion from non-neuronal cells |
US7138127B1 (en) * | 2000-01-19 | 2006-11-21 | Allergan, Inc. | Clostridial toxin derivatives and methods for treating pain |
US20040009180A1 (en) * | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
WO2004010934A2 (en) | 2002-07-29 | 2004-02-05 | Rajiv Doshi | Methods for the use of neurotoxin in the treatment of urologic disorders |
GB0321344D0 (en) * | 2003-09-11 | 2003-10-15 | Health Prot Agency | Re-targeted toxin conjugates |
GB0328060D0 (en) | 2003-12-04 | 2004-01-07 | Sod Conseils Rech Applic | Botulinum toxin treatment |
US20100266638A1 (en) * | 2004-02-26 | 2010-10-21 | Allergan, Inc. | Headache treatment method |
US9078892B2 (en) * | 2004-02-26 | 2015-07-14 | Allergan, Inc. | Methods for treating pain and for treating a medication overuse disorder |
US20080097219A1 (en) * | 2004-07-20 | 2008-04-24 | Allergan , Inc. | Thermographic Assessment Of Clostridial Toxin Applications |
JP5089388B2 (ja) * | 2004-09-01 | 2012-12-05 | アラーガン、インコーポレイテッド | 分解可能なクロストリジウム毒素 |
EP1824971B1 (en) * | 2004-11-22 | 2016-01-13 | New York University | Genetically engineered clostridial genes, proteins encoded by the engineered genes, and uses thereof |
EP1877073B1 (en) | 2004-12-01 | 2013-09-25 | The Secretary of State for Health | Non-cytotoxic protein conjugates |
PL1830872T3 (pl) | 2004-12-01 | 2011-09-30 | Sec Dep For Health | Białka fuzyjne |
GB0426397D0 (en) | 2004-12-01 | 2005-01-05 | Health Prot Agency | Fusion proteins |
WO2007044748A2 (en) * | 2005-10-11 | 2007-04-19 | University Of Pittsburgh | Sphingomyelin liposomes for the treatment of hyperactive bladder disorders |
US20090304747A1 (en) | 2006-05-16 | 2009-12-10 | Mayo Foundation For Medical Education And Research | Use of dmso and botulinum toxin therapy for urinary incontinence and related disorders |
GB0610868D0 (en) | 2006-06-01 | 2006-07-12 | Syntaxin Ltd | Treatment of pain |
GB0610867D0 (en) * | 2006-06-01 | 2006-07-12 | Syntaxin Ltd | Treatment of pain |
US9061025B2 (en) * | 2006-08-31 | 2015-06-23 | Allergan, Inc. | Methods for selecting headache patients responsive to botulinum toxin therapy |
EP2211890A1 (en) | 2007-10-23 | 2010-08-04 | Allergan, Inc. | Methods of treating urogenital-neurological disorders using modified clostridial toxins |
US20100303756A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Urogenital-Neurological Disorders Using Interleukin Retargeted Endopepidases |
US20100303783A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Urogenital-Neurological Disorders Using Tachykinin Retargeted Endopepidases |
US20100303798A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Urogenital-Neurological Disorders Using Neurotrophin Retargeted Endopepidases |
US20120251519A1 (en) * | 2011-03-29 | 2012-10-04 | Allergan, Inc. | Endopeptidase Treatment of Smooth Muscle Disorders |
US9144600B2 (en) * | 2011-07-14 | 2015-09-29 | Allergan, Inc. | Methods for treatment of incontinence associated with sexual activity |
EP2934571B1 (en) * | 2012-12-18 | 2018-05-30 | Allergan, Inc. | Prophylactic treatment of herpes recurrence |
-
2008
- 2008-10-21 EP EP08841644A patent/EP2211890A1/en not_active Withdrawn
- 2008-10-21 RU RU2010120017/15A patent/RU2491086C2/ru not_active IP Right Cessation
- 2008-10-21 CA CA2703370A patent/CA2703370A1/en not_active Abandoned
- 2008-10-21 CN CN2008801224290A patent/CN101918021A/zh active Pending
- 2008-10-21 KR KR1020107011141A patent/KR20100087019A/ko not_active Application Discontinuation
- 2008-10-21 JP JP2010531158A patent/JP2011514308A/ja active Pending
- 2008-10-21 WO PCT/US2008/080571 patent/WO2009055351A1/en active Application Filing
- 2008-10-21 NZ NZ585108A patent/NZ585108A/xx not_active IP Right Cessation
- 2008-10-21 RU RU2010120016/15A patent/RU2010120016A/ru not_active Application Discontinuation
- 2008-10-21 SG SG2012079265A patent/SG185338A1/en unknown
- 2008-10-21 AU AU2008316989A patent/AU2008316989A1/en not_active Abandoned
- 2008-10-21 US US12/255,369 patent/US9370548B2/en not_active Expired - Fee Related
- 2008-10-21 MX MX2010004502A patent/MX2010004502A/es active IP Right Grant
- 2008-10-21 BR BRPI0817775 patent/BRPI0817775A2/pt not_active IP Right Cessation
-
2010
- 2010-04-22 IL IL205279A patent/IL205279A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
MX2010004502A (es) | 2010-06-17 |
JP2011514308A (ja) | 2011-05-06 |
WO2009055351A1 (en) | 2009-04-30 |
AU2008316989A1 (en) | 2009-04-30 |
KR20100087019A (ko) | 2010-08-02 |
US20090117157A1 (en) | 2009-05-07 |
RU2491086C2 (ru) | 2013-08-27 |
CA2703370A1 (en) | 2009-04-30 |
NZ585108A (en) | 2012-09-28 |
EP2211890A1 (en) | 2010-08-04 |
IL205279A0 (en) | 2011-07-31 |
US9370548B2 (en) | 2016-06-21 |
CN101918021A (zh) | 2010-12-15 |
RU2010120016A (ru) | 2011-11-27 |
SG185338A1 (en) | 2012-11-29 |
RU2010120017A (ru) | 2011-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |