BRPI0418181A - emprego de 2-aminotetralinas substituìdas para prevenção do tratamento de morbus parkinson - Google Patents
emprego de 2-aminotetralinas substituìdas para prevenção do tratamento de morbus parkinsonInfo
- Publication number
- BRPI0418181A BRPI0418181A BRPI0418181-6A BRPI0418181A BRPI0418181A BR PI0418181 A BRPI0418181 A BR PI0418181A BR PI0418181 A BRPI0418181 A BR PI0418181A BR PI0418181 A BRPI0418181 A BR PI0418181A
- Authority
- BR
- Brazil
- Prior art keywords
- substituted
- aminotetralines
- morbus parkinson
- prevent treatment
- parkinson
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"EMPREGO DE 2-AMINOTETRALINAS SUBSTITUìDAS PARA PREVENçãO DO TRATAMENTO DE MORBUS PARKINSON". A presente invenção refere-se ao emprego de 2-aminotetralinas de fórmula geral (I) como medicamento para prevenção de Morbus Parkinson.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10361258A DE10361258A1 (de) | 2003-12-24 | 2003-12-24 | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
PCT/EP2004/014656 WO2005063238A1 (de) | 2003-12-24 | 2004-12-23 | Verwendung von substituierten 2-aminotetralinen zur vorbeugenden behandlung von morbus parkinson |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0418181A true BRPI0418181A (pt) | 2007-04-27 |
Family
ID=34706586
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0418181-6A BRPI0418181A (pt) | 2003-12-24 | 2004-12-23 | emprego de 2-aminotetralinas substituìdas para prevenção do tratamento de morbus parkinson |
Country Status (28)
Country | Link |
---|---|
US (1) | US8283376B2 (pt) |
EP (1) | EP1696905B1 (pt) |
JP (1) | JP5085938B2 (pt) |
KR (1) | KR20060125799A (pt) |
CN (1) | CN1897934B (pt) |
AT (1) | ATE389395T1 (pt) |
AU (1) | AU2004308649B2 (pt) |
BR (1) | BRPI0418181A (pt) |
CA (1) | CA2546797A1 (pt) |
CY (1) | CY1107956T1 (pt) |
DE (2) | DE10361258A1 (pt) |
DK (1) | DK1696905T3 (pt) |
EA (1) | EA011387B1 (pt) |
ES (1) | ES2303123T3 (pt) |
HK (1) | HK1094425A1 (pt) |
HR (1) | HRP20080175T3 (pt) |
IL (1) | IL175762A (pt) |
IS (1) | IS2517B (pt) |
MX (1) | MXPA06006693A (pt) |
NO (1) | NO20063275L (pt) |
NZ (1) | NZ547673A (pt) |
PL (1) | PL1696905T3 (pt) |
PT (1) | PT1696905E (pt) |
RS (1) | RS50578B (pt) |
SI (1) | SI1696905T1 (pt) |
UA (1) | UA83691C2 (pt) |
WO (1) | WO2005063238A1 (pt) |
ZA (1) | ZA200604114B (pt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
DE10041479A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
DE10234673B4 (de) * | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
US8246979B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
US8246980B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
DE10261696A1 (de) * | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
DE10361259A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes |
US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
DE102004014841B4 (de) * | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
WO2009068520A2 (en) | 2007-11-28 | 2009-06-04 | Schwarz Pharma Ag | Polymorphic form of rotigotine |
CA2735101C (en) * | 2008-10-13 | 2015-09-29 | Interquim, S.A. | Process for the preparation of optically active (s)-(-)-2-(n-propylamino)-5-methoxytetraline and (s)-(-)-2-(n-propylamino)-5-hydroxytetraline compounds |
EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
EP2478375B1 (en) * | 2009-09-16 | 2015-04-15 | United Arab Emirates University | Diagnostic agent for parkinson's disease |
CA2777358A1 (en) * | 2009-10-16 | 2011-04-21 | Epiomed Therapeutics, Inc. | Emesis treatment |
EA025584B1 (ru) | 2009-12-22 | 2017-01-30 | ЮСиБи ФАРМА ГМБХ | Поливинилпирролидон для стабилизации твердой дисперсии некристаллической формы ротиготина |
US9956201B2 (en) | 2014-07-21 | 2018-05-01 | Spriaso Llc | Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms |
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US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
DE60100595T2 (de) * | 2001-05-08 | 2004-06-24 | Lts Lohmann Therapie-Systeme Ag | Verbessertes transdermales therapeutisches System zur Behandlung von Morbus Parkinson |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
EP1344522A1 (en) | 2001-05-08 | 2003-09-17 | Schwarz Pharma Ag | Transdermal therapeutic system for Parkinson's disease inducing high plasma levels of rotigotine |
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FR2828212B1 (fr) | 2001-08-03 | 2003-10-31 | Aventis Pharma Sa | Methodes de diagnostic et de pronostic de la maladie de parkinson |
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US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
EP1386604A1 (en) | 2002-07-30 | 2004-02-04 | Schwarz Pharma Ag | Improved transdermal delivery system |
EP1386605A1 (en) | 2002-07-30 | 2004-02-04 | Schwarz Pharma Ag | Improved transdermal delivery system for the administration of rotigotine |
US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
US8246979B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
ATE295726T1 (de) * | 2002-12-02 | 2005-06-15 | Sanol Arznei Schwarz Gmbh | Verabreichung von rotigotine zur behandlung der parkinson'schen krankheit durch iontophorese |
DE10261696A1 (de) * | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
DE10334188B4 (de) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
DE10334187A1 (de) * | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
EP1547592A1 (en) * | 2003-12-23 | 2005-06-29 | Schwarz Pharma Ag | Intranasal formulation of rotigotine |
DE10361259A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes |
DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
CA2554616A1 (en) | 2004-01-22 | 2005-08-04 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and a dopamine agonist |
US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
DE102004014841B4 (de) * | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
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FR2882365B1 (fr) * | 2005-02-21 | 2007-09-07 | Sanofi Aventis Sa | Derives de 2-(1,5-diphenyl-1h-pyrazol-3-yl)-1,3,4-oxadiazole leur preparation et leur application en therapeutique |
TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
WO2009068520A2 (en) * | 2007-11-28 | 2009-06-04 | Schwarz Pharma Ag | Polymorphic form of rotigotine |
-
2003
- 2003-12-24 DE DE10361258A patent/DE10361258A1/de not_active Ceased
-
2004
- 2004-12-23 JP JP2006546072A patent/JP5085938B2/ja not_active Expired - Fee Related
- 2004-12-23 SI SI200430713T patent/SI1696905T1/sl unknown
- 2004-12-23 DK DK04804250T patent/DK1696905T3/da active
- 2004-12-23 US US10/585,609 patent/US8283376B2/en not_active Expired - Fee Related
- 2004-12-23 ES ES04804250T patent/ES2303123T3/es active Active
- 2004-12-23 DE DE502004006619T patent/DE502004006619D1/de active Active
- 2004-12-23 AT AT04804250T patent/ATE389395T1/de active
- 2004-12-23 BR BRPI0418181-6A patent/BRPI0418181A/pt not_active IP Right Cessation
- 2004-12-23 KR KR1020067011509A patent/KR20060125799A/ko not_active IP Right Cessation
- 2004-12-23 CN CN2004800384631A patent/CN1897934B/zh not_active Expired - Fee Related
- 2004-12-23 RS RSP-2008/0189A patent/RS50578B/sr unknown
- 2004-12-23 UA UAA200605754A patent/UA83691C2/ru unknown
- 2004-12-23 EP EP04804250A patent/EP1696905B1/de active Active
- 2004-12-23 MX MXPA06006693A patent/MXPA06006693A/es active IP Right Grant
- 2004-12-23 PT PT04804250T patent/PT1696905E/pt unknown
- 2004-12-23 CA CA002546797A patent/CA2546797A1/en not_active Abandoned
- 2004-12-23 EA EA200600971A patent/EA011387B1/ru not_active IP Right Cessation
- 2004-12-23 AU AU2004308649A patent/AU2004308649B2/en not_active Ceased
- 2004-12-23 PL PL04804250T patent/PL1696905T3/pl unknown
- 2004-12-23 WO PCT/EP2004/014656 patent/WO2005063238A1/de active Application Filing
- 2004-12-23 NZ NZ547673A patent/NZ547673A/en not_active IP Right Cessation
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2006
- 2006-05-18 IL IL175762A patent/IL175762A/en not_active IP Right Cessation
- 2006-05-19 ZA ZA200604114A patent/ZA200604114B/xx unknown
- 2006-05-26 IS IS8485A patent/IS2517B/is unknown
- 2006-07-14 NO NO20063275A patent/NO20063275L/no not_active Application Discontinuation
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2007
- 2007-02-07 HK HK07101435A patent/HK1094425A1/xx not_active IP Right Cessation
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2008
- 2008-04-16 HR HR20080175T patent/HRP20080175T3/xx unknown
- 2008-05-23 CY CY20081100530T patent/CY1107956T1/el unknown
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Owner name: UCB PHARMA GMBH (DE) Free format text: NOME ALTERADO DE: SCHWARZ PHARMA AG |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |