BRPI0408247A - usos de antagonistas e agonistas de il-23 e reagentes relacionados - Google Patents

usos de antagonistas e agonistas de il-23 e reagentes relacionados

Info

Publication number
BRPI0408247A
BRPI0408247A BRPI0408247-8A BRPI0408247A BRPI0408247A BR PI0408247 A BRPI0408247 A BR PI0408247A BR PI0408247 A BRPI0408247 A BR PI0408247A BR PI0408247 A BRPI0408247 A BR PI0408247A
Authority
BR
Brazil
Prior art keywords
agonists
antagonists
related reagents
methods
reagents
Prior art date
Application number
BRPI0408247-8A
Other languages
English (en)
Inventor
Martin Oft
Terrill K Mcclanahan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of BRPI0408247A publication Critical patent/BRPI0408247A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"USOS DE ANTAGONISTAS E AGONISTAS DE IL-23 E REAGENTES RELACIONADOS". A presente invenção refere-se a métodos de tratamento para tumores. Em particular, métodos que são providos para a modulação de atividade de uma molécula de citocina e seu receptor.
BRPI0408247-8A 2003-03-10 2004-03-09 usos de antagonistas e agonistas de il-23 e reagentes relacionados BRPI0408247A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45367203P 2003-03-10 2003-03-10
PCT/US2004/007198 WO2004081190A2 (en) 2003-03-10 2004-03-09 Uses of il-23 agonists and antagonists; related reagents

Publications (1)

Publication Number Publication Date
BRPI0408247A true BRPI0408247A (pt) 2006-03-01

Family

ID=32990805

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408247-8A BRPI0408247A (pt) 2003-03-10 2004-03-09 usos de antagonistas e agonistas de il-23 e reagentes relacionados

Country Status (23)

Country Link
US (4) US7282204B2 (pt)
EP (2) EP2108658B1 (pt)
JP (4) JP4605798B2 (pt)
CN (1) CN1759123B (pt)
AT (1) ATE440864T1 (pt)
AU (2) AU2004219625B9 (pt)
BR (1) BRPI0408247A (pt)
CA (1) CA2518262C (pt)
CL (1) CL2004000467A1 (pt)
CY (1) CY1109468T1 (pt)
DE (1) DE602004022781D1 (pt)
DK (1) DK1601694T3 (pt)
ES (1) ES2330220T3 (pt)
HK (1) HK1076477A1 (pt)
MX (1) MXPA05009717A (pt)
NO (1) NO20054630L (pt)
NZ (2) NZ541898A (pt)
PL (1) PL1601694T3 (pt)
PT (1) PT1601694E (pt)
SI (1) SI1601694T1 (pt)
TW (2) TWI439285B (pt)
WO (1) WO2004081190A2 (pt)
ZA (1) ZA200506879B (pt)

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CN1942201B (zh) * 2004-02-17 2012-06-20 先灵公司 调节il-23活性的方法；相关试剂
EP1756138A4 (en) * 2004-03-05 2009-07-01 Archemix Corp HUMAN CYTOKINE FAMILY BINDING APTAMERS AND THEIR USE AS THERAPEUTIC AGENTS OF AUTOIMMUNE DISEASES
US20060193821A1 (en) * 2004-03-05 2006-08-31 Diener John L Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
AR051444A1 (es) * 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
TWI363091B (en) * 2004-12-20 2012-05-01 Schering Corp Uses of mammalian cytokine; related reagents
CA2613818C (en) * 2005-06-30 2013-08-27 Centocor, Inc. Anti-il-23 antibodies, compositions, methods and uses
AU2012258409B2 (en) * 2005-06-30 2016-01-07 Centocor, Inc. Anti-IL-23 antibodies, compositions, methods and uses
JP2009500021A (ja) * 2005-06-30 2009-01-08 アーケミックス コーポレイション サイトカインのｉｌ−１２ファミリーのポリヌクレオチドおよびポリペプチド
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EP1882699A1 (en) * 2006-07-27 2008-01-30 Heinfried Radeke Regulation of interleukin-23
TWI426918B (zh) * 2007-02-12 2014-02-21 Merck Sharp & Dohme Ｉｌ-２３拮抗劑於治療感染之用途
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BRPI0807991A2 (pt) 2007-02-28 2014-06-17 Schering Corp Anticorpos anti-il-23r elaborados.
CN101668531B (zh) 2007-02-28 2014-05-07 默沙东公司 用于治疗免疫病症的联合治疗
AU2008273814A1 (en) * 2007-07-06 2009-01-15 Valorisation Hsj, Societe En Commandite IL-23 receptor antagonists and uses thereof
AR068723A1 (es) * 2007-10-05 2009-12-02 Glaxo Group Ltd Proteina que se une a antigenos que se une a il-23 humana y sus usos
JPWO2009054454A1 (ja) 2007-10-24 2011-03-03 国立大学法人 東京医科歯科大学 カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤
NZ623706A (en) 2008-05-05 2015-12-24 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
WO2010027767A1 (en) * 2008-08-27 2010-03-11 Schering Corporation Engineered anti-il-23r antibodies
WO2010036924A2 (en) * 2008-09-25 2010-04-01 The United States Of America, As Represented By The Secretary, Department Of Healthe And Human Serv. Inflammatory genes and microrna-21 as biomarkers for colon cancer prognosis
DK2350316T3 (da) * 2008-10-20 2014-05-05 Valipharma Fremgangsmåder og anvendelser der involverer genetiske aberrationer af nav3 og aberrerende ekspression af multiple gener
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Also Published As

Publication number Publication date
WO2004081190A3 (en) 2005-02-03
AU2010212372A1 (en) 2010-09-09
WO2004081190A2 (en) 2004-09-23
ES2330220T3 (es) 2009-12-07
CN1759123A (zh) 2006-04-12
US7282204B2 (en) 2007-10-16
EP2108658B1 (en) 2016-06-08
ATE440864T1 (de) 2009-09-15
US8034341B2 (en) 2011-10-11
CL2004000467A1 (es) 2005-05-06
AU2004219625B2 (en) 2010-08-19
JP2006520781A (ja) 2006-09-14
TWI357336B (en) 2012-02-01
DK1601694T3 (da) 2009-12-14
PL1601694T3 (pl) 2010-02-26
AU2010212372B2 (en) 2012-12-20
JP4605798B2 (ja) 2011-01-05
NO20054630D0 (no) 2005-10-07
TWI439285B (zh) 2014-06-01
EP2108658A1 (en) 2009-10-14
AU2004219625A1 (en) 2004-09-23
DE602004022781D1 (de) 2009-10-08
AU2004219625B9 (en) 2010-12-23
CA2518262C (en) 2014-05-06
ZA200506879B (en) 2006-05-31
US20080057058A1 (en) 2008-03-06
EP1601694A2 (en) 2005-12-07
NZ567860A (en) 2009-11-27
PT1601694E (pt) 2009-12-03
US20120034219A1 (en) 2012-02-09
CN1759123B (zh) 2011-04-13
SI1601694T1 (sl) 2010-01-29
HK1076477A1 (en) 2006-01-20
JP2007197453A (ja) 2007-08-09
US20100003251A1 (en) 2010-01-07
CA2518262A1 (en) 2004-09-23
TW201141521A (en) 2011-12-01
JP2014005286A (ja) 2014-01-16
JP2011032275A (ja) 2011-02-17
TW200505479A (en) 2005-02-16
NZ541898A (en) 2008-07-31
MXPA05009717A (es) 2005-10-18
US20040223969A1 (en) 2004-11-11
NO20054630L (no) 2005-10-07
EP1601694B1 (en) 2009-08-26
CY1109468T1 (el) 2014-08-13

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

B25G Requested change of headquarter approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

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