BR9809433A - Moléculas de dna enzimáticas - Google Patents

Moléculas de dna enzimáticas

Info

Publication number
BR9809433A
BR9809433A BR9809433-5A BR9809433A BR9809433A BR 9809433 A BR9809433 A BR 9809433A BR 9809433 A BR9809433 A BR 9809433A BR 9809433 A BR9809433 A BR 9809433A
Authority
BR
Brazil
Prior art keywords
dna molecules
enzymatic dna
compositions
enzymes
molecules
Prior art date
Application number
BR9809433-5A
Other languages
English (en)
Other versions
BRPI9809433B1 (pt
Inventor
Gerald F Joyce
Ronald R Breaker
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of BR9809433A publication Critical patent/BR9809433A/pt
Publication of BRPI9809433B1 publication Critical patent/BRPI9809433B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Patente de Invenção:<B>"MOLéCULAS DE DNA ENZIMáTICAS"<D>. A presente invenção refere-se a enzimas de ácido desoxirribonucléico - moléculas de DNA catalíticas ou enzimáticas - capazes de clivar seq³ências ou moléculas de ácidos nucléicos, particularmente RNA, de maneira específica para sítio, bem como composições que incluem as mesmas. Também estão descritos métodos para fazer e usar as enzimas e composições descritas.
BRPI9809433A 1997-04-29 1998-04-29 moléculas de dna enzimáticas BRPI9809433B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4522897P 1997-04-29 1997-04-29
PCT/US1998/008677 WO1998049346A1 (en) 1997-04-29 1998-04-29 Enzymatic dna molecules

Publications (2)

Publication Number Publication Date
BR9809433A true BR9809433A (pt) 2000-06-13
BRPI9809433B1 BRPI9809433B1 (pt) 2015-09-08

Family

ID=21936713

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9809433A BRPI9809433B1 (pt) 1997-04-29 1998-04-29 moléculas de dna enzimáticas

Country Status (7)

Country Link
EP (2) EP2275546A3 (pt)
JP (2) JP4203126B2 (pt)
CN (1) CN1261920A (pt)
AU (1) AU735522C (pt)
BR (1) BRPI9809433B1 (pt)
CA (1) CA2287520C (pt)
WO (1) WO1998049346A1 (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH057771U (ja) * 1991-07-16 1993-02-02 株式会社イナツクス 自動洗浄装置付き小便器
AU768627B2 (en) * 1998-03-05 2003-12-18 Johnson & Johnson Research Pty. Limited Zymogenic nucleic acid detection methods, and related molecules and kits
AU5298699A (en) * 1998-08-13 2000-03-06 Johnson & Johnson Research Pty. Limited Dnazymes and methods for treating hpv-related disorders
CN1323344A (zh) * 1998-08-13 2001-11-21 庄臣及庄臣研究股份有限公司 治疗再狭窄的DNAzyme和方法
AUPP810399A0 (en) * 1999-01-11 1999-02-04 Unisearch Limited Catalytic molecules
AUPQ201499A0 (en) * 1999-08-04 1999-08-26 Unisearch Limited Treatment of inflammatory and malignant diseases
EP1212416A2 (en) * 1999-08-31 2002-06-12 Ribozyme Pharmaceuticals, Inc. Nucleic acid based modulators of gene expression
US6706474B1 (en) 2000-06-27 2004-03-16 Board Of Trustees Of The University Of Illinois Nucleic acid enzyme biosensors for ions
US7534560B2 (en) 2002-05-10 2009-05-19 The Board Of Trustees Of The University Of Illinois Simple catalytic DNA biosensors for ions based on color changes
US6890719B2 (en) 2002-05-10 2005-05-10 The Board Of Trustess Of The University Of Illinois Fluorescence based biosensor
US7612185B2 (en) 2003-03-07 2009-11-03 The Board Of Trustees Of The University Of Illinois Nucleic acid biosensors
US7485419B2 (en) 2004-01-13 2009-02-03 The Board Of Trustees Of The University Of Illinois Biosensors based on directed assembly of particles
US7892734B2 (en) 2005-08-11 2011-02-22 The Board Of Trustees Of The University Of Illinois Aptamer based colorimetric sensor systems
BRPI0616466B1 (pt) 2005-10-07 2021-01-26 Johnson & Johnson Research Pty Limited composição de enzimas de ácido nucleico multicomponentes (mnazima), métodos para detectar a presença de pelo menos um facilitador de combinação, um alvo e uma variante de sequência de ácidos nucléicos, métodos para fabricar uma pluraridade de mnazima, testar sequências de núcleo catalítico parcial e identificar suas posições, bem como uso de pelo menos um oligonucleotídeo
WO2007109500A1 (en) 2006-03-16 2007-09-27 The Board Of Trustees Of The University Of Illinois Lateral flow devices
ES2520023T3 (es) 2006-10-06 2014-11-11 Speedx Pty Ltd Interruptores moleculares y métodos para su uso
WO2008089248A2 (en) 2007-01-19 2008-07-24 The Board Of Trustees Of The University Of Illinois Amphiphilic substances and triggered liberation from lipid vesicles
KR101583834B1 (ko) 2007-04-05 2016-01-19 존슨 앤드 존슨 리서치 피티와이 리미티드 핵산 효소 및 복합체 및 이의 사용 방법
US8058415B2 (en) 2007-04-24 2011-11-15 The Board Of Trustees Of The University Of Illinois Aptamer- and nucleic acid enzyme-based systems for simultaneous detection of multiple analytes
US8409800B2 (en) 2007-07-16 2013-04-02 The Board Of Trustees Of The University Of Illinois Nucleic acid based fluorescent sensor for copper detection
US8568690B2 (en) 2007-07-31 2013-10-29 The Board Of Trustees Of The University Of Illinois MRI contrast agents and high-throughput screening by MRI
WO2009045632A2 (en) 2007-08-10 2009-04-09 The Board Of Trustees Of The University Of Illinois Nucleic acid based fluorescent sensor for mercury detection
US8062893B2 (en) 2008-10-10 2011-11-22 The Board Of Trustees Of The University Of Illinois Fluorescent sensor for mercury
US8815156B2 (en) 2010-07-19 2014-08-26 Andalyze, Inc. Sensor housing and reagent chemistry
CN104830862B (zh) * 2015-05-08 2018-04-27 蚌埠医学院 一种抗乙型肝炎病毒的脱氧核酶10-23及其应用
CN104845969B (zh) * 2015-05-08 2018-06-15 首都师范大学 一种调控和提高脱氧核酶催化活性的方法
GB201817990D0 (en) * 2018-11-02 2018-12-19 Univ Of Essex Enterprise Limited Enzymatic nucleic acid molecules
JP7437020B2 (ja) * 2020-03-19 2024-02-22 国立研究開発法人産業技術総合研究所 Ｄｎａ酵素及びｒｎａ切断方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378825A (en) 1990-07-27 1995-01-03 Isis Pharmaceuticals, Inc. Backbone modified oligonucleotide analogs
EP0642589A4 (en) 1992-05-11 1997-05-21 Ribozyme Pharm Inc METHOD AND REAGENT TO INHIBIT VIRAL REPLICATION.
US5861288A (en) * 1993-10-18 1999-01-19 Ribozyme Pharmaceuticals, Inc. Catalytic DNA
US5807718A (en) 1994-12-02 1998-09-15 The Scripps Research Institute Enzymatic DNA molecules

Also Published As

Publication number Publication date
AU735522B2 (en) 2001-07-12
JP5066016B2 (ja) 2012-11-07
EP2275546A2 (en) 2011-01-19
CN1261920A (zh) 2000-08-02
AU735522C (en) 2005-04-07
JP4203126B2 (ja) 2008-12-24
AU7267598A (en) 1998-11-24
JP2002514080A (ja) 2002-05-14
CA2287520A1 (en) 1998-11-05
CA2287520C (en) 2010-12-14
EP0981646B1 (en) 2016-01-06
JP2009000117A (ja) 2009-01-08
WO1998049346A1 (en) 1998-11-05
EP2275546A3 (en) 2013-06-05
BRPI9809433B1 (pt) 2015-09-08
EP0981646A4 (en) 2002-05-29
EP0981646A1 (en) 2000-03-01

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Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion)
B09B Decision: refusal

Free format text: DE ACORDO COM O ART. 37, INDEFIRO O PRESENTE PEDIDO COM BASE NOS ART. 8O, 10 (VIII), 13, 24 E 25 DA LPI VIGENTE.

B12B Appeal: appeal against refusal
B07D Technical examination (opinion) related to article 229 of industrial property law
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B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/09/2015, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2512 DE 26-02-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.