BR0313173A - preparação farmacêutica que contém um composto de benzimidazol misto com celulose microcristalina, método para sua preparação, bem como uso da dita celulose microcristalina - Google Patents

preparação farmacêutica que contém um composto de benzimidazol misto com celulose microcristalina, método para sua preparação, bem como uso da dita celulose microcristalina

Info

Publication number
BR0313173A
BR0313173A BRPI0313173-4A BR0313173A BR0313173A BR 0313173 A BR0313173 A BR 0313173A BR 0313173 A BR0313173 A BR 0313173A BR 0313173 A BR0313173 A BR 0313173A
Authority
BR
Brazil
Prior art keywords
microcrystalline cellulose
well
benzimidazole compound
preparation
pharmaceutical preparation
Prior art date
Application number
BRPI0313173-4A
Other languages
English (en)
Inventor
Frank Muskulus
Peter Kraass
Andrea Burgenmeister
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10235475A external-priority patent/DE10235475B4/de
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Publication of BR0313173A publication Critical patent/BR0313173A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

PREPARAçãO FARMACêUTICA QUE CONTéM UM COMPOSTO DE BENZIMIDAZOL MISTO COM CELULOSE MICROCRISTALINA, MéTODO PARA SUA PREPARAçãO, BEM COMO USO DA DITA CELULOSE MICROCRISTALINA. A presente invenção refere-se a preparações farmacêuticas orais na forma de péletes em que um composto de benzimidazol é estabilizado combinando-o com celuose microcristalina.
BRPI0313173-4A 2002-08-02 2003-07-16 preparação farmacêutica que contém um composto de benzimidazol misto com celulose microcristalina, método para sua preparação, bem como uso da dita celulose microcristalina BR0313173A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40007102P 2002-08-02 2002-08-02
DE10235475A DE10235475B4 (de) 2002-08-02 2002-08-02 Arzneimittel mit einer Benzimidazolverbindung im Gemisch mit mikrokristalliner Cellulose und Verfahren zu deren Herstellung
PCT/EP2003/007741 WO2004014345A1 (en) 2002-08-02 2003-07-16 Pharmaceutical preparation containing a benzimidazole compound mixed with microcrystalline cellulose and a method for its preparation

Publications (1)

Publication Number Publication Date
BR0313173A true BR0313173A (pt) 2007-07-17

Family

ID=31716591

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0313173-4A BR0313173A (pt) 2002-08-02 2003-07-16 preparação farmacêutica que contém um composto de benzimidazol misto com celulose microcristalina, método para sua preparação, bem como uso da dita celulose microcristalina

Country Status (16)

Country Link
US (1) US7732474B2 (pt)
EP (1) EP1524967B1 (pt)
JP (1) JP2005536527A (pt)
AT (1) ATE388695T1 (pt)
AU (1) AU2003244647B2 (pt)
BR (1) BR0313173A (pt)
CA (1) CA2494716A1 (pt)
DE (1) DE60319707T2 (pt)
ES (1) ES2299710T3 (pt)
HK (1) HK1072195A1 (pt)
NO (1) NO20051018L (pt)
PL (1) PL208130B1 (pt)
PT (1) PT1524967E (pt)
RU (1) RU2332237C2 (pt)
WO (1) WO2004014345A1 (pt)
ZA (1) ZA200500324B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL130602A0 (en) 1999-06-22 2000-06-01 Dexcel Ltd Stable benzimidazole formulation
EP1720527A2 (en) * 2004-03-03 2006-11-15 Teva Pharmaceutical Industries Ltd A stable pharmaceutical composition comprising an acid labile drug
WO2006026829A1 (en) * 2004-09-09 2006-03-16 Metelli Pty Ltd Stable paste composition of enteric coated acid labile active agent and use thereof
EP1785135A1 (en) * 2005-11-10 2007-05-16 Laboratorios Del Dr. Esteve, S.A. New stabilized galenic formulations comprising lansoprazole and their preparation
JP2009538901A (ja) * 2006-06-01 2009-11-12 デクセル ファーマ テクノロジーズ エルティーディー． 複式ユニット製薬的製剤
EP2050439B1 (en) 2006-08-11 2016-11-23 Asahi Kasei Kabushiki Kaisha Process for production of spherical granule containing slightly water-soluble substance
US8911787B2 (en) * 2008-02-26 2014-12-16 Ranbaxy Laboratories Limited Stable oral benzimidazole compositions and process of preparation thereof
EP2319504A1 (en) * 2009-11-07 2011-05-11 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical solid dosage form
WO2012171540A1 (en) * 2011-06-15 2012-12-20 Bene-Arzneimittel Gmbh Suppository comprising pantoprazole comprised in pellets with a cellulose core
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
JP6168673B2 (ja) 2015-10-07 2017-07-26 協和発酵キリン株式会社 アリールアルキルアミン化合物含有医薬組成物
WO2017061621A1 (ja) * 2015-10-07 2017-04-13 協和発酵キリン株式会社 アリールアルキルアミン化合物含有医薬組成物
US10736855B2 (en) 2016-02-25 2020-08-11 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
EP3292862A1 (en) 2016-09-07 2018-03-14 Sandoz Ag Omeprazole formulations

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
JPH0733659A (ja) * 1992-07-17 1995-02-03 Yoshitomi Pharmaceut Ind Ltd 抗潰瘍剤含有製剤
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
DE69522921T2 (de) * 1994-07-08 2002-04-11 Astrazeneca Ab Aus mehreren einzeleinheiten zusammengesetzte dosierungsform in tablettenform (i)
ES2094694B1 (es) * 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
CH687810A5 (de) * 1995-05-24 1997-02-28 Mepha Ag Pelletformulierung mit Omeprazol.
US5824339A (en) * 1995-09-08 1998-10-20 Takeda Chemical Industries, Ltd Effervescent composition and its production
DE19626045C2 (de) 1996-06-28 1998-12-03 Klinge Co Chem Pharm Fab Stabile Arzneiform zur oralen Verabreichung, welche Omeprazol als aktiven Wirkstoff enthält, sowie Verfahren zur Herstellung derselben
AU731186B2 (en) * 1997-03-13 2001-03-29 Hexal Ag Stabilization of acid sensitive benzimidazols with amino acid/cyclodextrin combinations
ES2137862B1 (es) * 1997-07-31 2000-09-16 Intexim S A Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion.
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6228400B1 (en) 1999-09-28 2001-05-08 Carlsbad Technology, Inc. Orally administered pharmaceutical formulations of benzimidazole derivatives and the method of preparing the same
DE19959419A1 (de) * 1999-12-09 2001-06-21 Ratiopharm Gmbh Stabile galenische Zubereitungen umfassend ein Benzimidazol und Verfahren zu ihrer Herstellung
ES2244167T3 (es) * 1999-12-16 2005-12-01 Laboratorio Medinfar-Produtos Farmaceuticos, S.A. Nuevas preparaciones farmaceuticas multiunitarias estables que contienen bencimidazoles sustituidos.

Also Published As

Publication number Publication date
ZA200500324B (en) 2006-07-26
PT1524967E (pt) 2008-04-03
HK1072195A1 (en) 2005-08-19
CA2494716A1 (en) 2004-02-19
ES2299710T3 (es) 2008-06-01
ATE388695T1 (de) 2008-03-15
EP1524967B1 (en) 2008-03-12
WO2004014345A1 (en) 2004-02-19
RU2332237C2 (ru) 2008-08-27
US7732474B2 (en) 2010-06-08
EP1524967A1 (en) 2005-04-27
US20050129760A1 (en) 2005-06-16
AU2003244647A1 (en) 2004-02-25
PL374827A1 (en) 2005-10-31
RU2005102814A (ru) 2005-12-20
DE60319707T2 (de) 2008-07-17
PL208130B1 (pl) 2011-03-31
NO20051018L (no) 2005-02-24
DE60319707D1 (de) 2008-04-24
AU2003244647B2 (en) 2008-04-17
JP2005536527A (ja) 2005-12-02

Similar Documents

Publication Publication Date Title
BR0313173A (pt) preparação farmacêutica que contém um composto de benzimidazol misto com celulose microcristalina, método para sua preparação, bem como uso da dita celulose microcristalina
ECSP067110A (es) Derivados de 2-carbamida-4-feniltiazol, su preparación y su aplicación en terapéutica
AR106702A2 (es) Uso de un anticuerpo antagonista anti-ngf para la preparación de un medicamento
CR20120578A (es) Formulaciones de insulina de acción prolongada
ECSP055671A (es) Nuevas quinazolinonas espirocondensadas y su uso como inhibidores de la fosfodiesteresa
BRPI0915084B8 (pt) composto, e, composição farmacêutica
CL2007001784A1 (es) Compuestos derivados de benzoxazol de formula la, su composicion farmaceutica, metodo para medir in vivo depositos de amoloide empleando dicha composicion, y uso del compuesto la para preparar un medicamento, y compuesto de formula ib, y su uso como precursor en la preparacion de un compuesto marcado.
CL2012000024A1 (es) Composicion farmaceutica que comprende 100 a 2000 mg de metformina y 10 a 300 mg de un compuesto inhibidor de sglt-2 derivado de glucopiranosil fenil sustituidos, celulosa microcristalina, un aglutinante y croscaramelosa.
BRPI0311189B8 (pt) composições farmacêuticas contendo polimorfo a de flibanserin, bem como seu uso
BRPI0607413A2 (pt) composição farmacêutica compreendendo derivados de indolilmaleimida
UY29892A1 (es) Nuevos derivados de cromano, composiciones farmaceuticas conteniendolos, procesos de preparacion y aplicaciones
GT200900026A (es) Derivados de 5,6 -bisaril-2-piridin-carboxamida, su preparacion y su aplicacion en terapeutica como antagonistas de los receptores de urotensina ii
UY29234A1 (es) Derivados de adamantano, composiciones farmacéuticas que los contienen, procedimientos de preparación de ambos y aplicaciones.
BRPI0621347B8 (pt) composição farmacêutica para aumentar a produção de eritrócitos e para o tratamento de anemia
ECSP034754A (es) Derivados de beta-carbolina y su uso farmaceutico contra depresion y ansiedad
UY30356A1 (es) Derivados de 3-halo-n-(2.(4-fluorofenil)-4-oxobutil)-n-metil-5-(trifluorometil)benzamida y composiciones de los mismos.
PL1868631T3 (pl) Zastosowanie związków indukujących syntezę białek SIRT przy lub dla otrzymywania kompozycji kosmetycznej lub farmaceutycznej
BRPI0512986A (pt) novos derivados de hidantoìna
UY28917A1 (es) Derivados de tetrahidroisoquinolilsulfonamidas composiciones farmaceuticas y su uso terapeutico
UY29069A1 (es) Uso de compuestos tpo miméticos y composiciones farmacéuticas para el tratamiento de la anemia
AR048672A1 (es) Tabletas de desintegracion que comprenden licarbazepina
AR063597A1 (es) Nueva sal
ECSP088574A (es) Derivados de 2-carbamida-4-feniltiazol, su preparación y su aplicación en terapéutica
CR7672A (es) Metodo microbiologico para la produccion de 11- alfa- hidroxiesteroides 7- alfa sustituidos
UY30235A1 (es) Inhibidores de la adenilato ciclasa soluble

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2064 DE 27/07/2010.