BG22815A3 - Метод за получаване на 2,6-диамино-дихидропиридини - Google Patents

Метод за получаване на 2,6-диамино-дихидропиридини

Info

Publication number
BG22815A3
BG22815A3 BG022858A BG2285873A BG22815A3 BG 22815 A3 BG22815 A3 BG 22815A3 BG 022858 A BG022858 A BG 022858A BG 2285873 A BG2285873 A BG 2285873A BG 22815 A3 BG22815 A3 BG 22815A3
Authority
BG
Bulgaria
Prior art keywords
dihydropyridines
diamino
preparation
Prior art date
Application number
BG022858A
Other languages
English (en)
Inventor
Horst Meyer
Friedrich Bossert
Wulf Vater
Kurt Stopel
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of BG22815A3 publication Critical patent/BG22815A3/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
BG022858A 1972-03-06 1973-02-28 Метод за получаване на 2,6-диамино-дихидропиридини BG22815A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2210687A DE2210687C3 (de) 1972-03-06 1972-03-06 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BG22815A3 true BG22815A3 (bg) 1977-04-20

Family

ID=5838037

Family Applications (2)

Application Number Title Priority Date Filing Date
BG022858A BG22815A3 (bg) 1972-03-06 1973-02-28 Метод за получаване на 2,6-диамино-дихидропиридини
BG024472A BG20583A3 (bg) 1972-03-06 1973-02-28 Метод за получаване на 2,6-диамино-дихидропиридини

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG024472A BG20583A3 (bg) 1972-03-06 1973-02-28 Метод за получаване на 2,6-диамино-дихидропиридини

Country Status (24)

Country Link
JP (2) JPS5626659B2 (bg)
KR (1) KR780000119B1 (bg)
AT (3) AT327904B (bg)
BE (1) BE796279A (bg)
BG (2) BG22815A3 (bg)
CA (1) CA988524A (bg)
CH (2) CH577473A5 (bg)
CS (2) CS182792B2 (bg)
DD (1) DD106833A5 (bg)
DE (1) DE2210687C3 (bg)
DK (1) DK136061C (bg)
ES (1) ES412323A1 (bg)
FI (1) FI55996C (bg)
FR (1) FR2181789B1 (bg)
GB (1) GB1379005A (bg)
HU (1) HU167089B (bg)
IE (1) IE37370B1 (bg)
IL (1) IL41664A (bg)
LU (1) LU67147A1 (bg)
NL (1) NL7303137A (bg)
PL (2) PL92078B1 (bg)
RO (2) RO61192A (bg)
SE (1) SE384208B (bg)
ZA (1) ZA731501B (bg)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210687C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE2406198C2 (de) * 1974-02-09 1983-12-15 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von neuen 2-Amino-6-dialkylamino-dihydropyridinen
JPS5922593U (ja) * 1982-08-03 1984-02-10 日本マランツ株式会社 ヘツドホ−ン用ホ−ン部取付構造
JPS5922594U (ja) * 1982-08-03 1984-02-10 日本マランツ株式会社 耳栓型ヘツドホ−ン
JPS6282898A (ja) * 1985-10-08 1987-04-16 Matsushita Electric Ind Co Ltd ヘツドホン
JPS6293060U (bg) * 1985-11-28 1987-06-13

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3855231A (en) * 1972-03-06 1974-12-17 Bayer Ag 2,6-diamino-1,4-dihydropyridine derivatives
DE2210687C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2,6-Diamino-3,5-diäthoxycarbonyldihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE2406198C2 (de) * 1974-02-09 1983-12-15 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von neuen 2-Amino-6-dialkylamino-dihydropyridinen

Also Published As

Publication number Publication date
CH580589A5 (bg) 1976-10-15
GB1379005A (en) 1975-01-02
ZA731501B (en) 1973-11-28
DE2210687A1 (de) 1973-09-20
DE2210687C3 (de) 1981-09-24
JPS5699460A (en) 1981-08-10
DK136061C (da) 1978-01-02
HU167089B (bg) 1975-08-28
PL89256B1 (bg) 1976-11-30
JPS5626659B2 (bg) 1981-06-19
RO63068A (bg) 1978-05-15
DD106833A5 (bg) 1974-07-05
IL41664A (en) 1976-01-30
ES412323A1 (es) 1976-01-01
BG20583A3 (bg) 1975-12-05
ATA925774A (de) 1975-05-15
DE2210687B2 (de) 1980-09-04
IE37370B1 (en) 1977-07-06
CA988524A (en) 1976-05-04
JPS5911584B2 (ja) 1984-03-16
KR780000119B1 (en) 1978-04-15
SE384208B (sv) 1976-04-26
FR2181789A1 (bg) 1973-12-07
AT327904B (de) 1976-02-25
CS182781B2 (en) 1978-05-31
IL41664A0 (en) 1973-05-31
DK136061B (da) 1977-08-08
FI55996C (fi) 1979-11-12
AT324338B (de) 1975-08-25
FR2181789B1 (bg) 1976-12-03
PL92078B1 (bg) 1977-03-31
JPS48103579A (bg) 1973-12-25
RO61192A (bg) 1976-09-15
CS182792B2 (en) 1978-05-31
LU67147A1 (bg) 1973-05-22
CH577473A5 (bg) 1976-07-15
BE796279A (fr) 1973-09-05
NL7303137A (bg) 1973-09-10
FI55996B (fi) 1979-07-31
IE37370L (en) 1973-09-06

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