AU9646198A - Isoquinoline derivative and drug - Google Patents

Isoquinoline derivative and drug

Info

Publication number
AU9646198A
AU9646198A AU96461/98A AU9646198A AU9646198A AU 9646198 A AU9646198 A AU 9646198A AU 96461/98 A AU96461/98 A AU 96461/98A AU 9646198 A AU9646198 A AU 9646198A AU 9646198 A AU9646198 A AU 9646198A
Authority
AU
Australia
Prior art keywords
drug
isoquinoline derivative
isoquinoline
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU96461/98A
Inventor
Hiroyoshi Hidaka
Akira Matsuura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of AU9646198A publication Critical patent/AU9646198A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU96461/98A 1997-10-22 1998-10-22 Isoquinoline derivative and drug Abandoned AU9646198A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP28968897 1997-10-22
JP9-289688 1997-10-22
PCT/JP1998/004781 WO1999020620A1 (en) 1997-10-22 1998-10-22 Isoquinoline derivative and drug

Publications (1)

Publication Number Publication Date
AU9646198A true AU9646198A (en) 1999-05-10

Family

ID=17746466

Family Applications (1)

Application Number Title Priority Date Filing Date
AU96461/98A Abandoned AU9646198A (en) 1997-10-22 1998-10-22 Isoquinoline derivative and drug

Country Status (3)

Country Link
JP (1) JP4316794B2 (en)
AU (1) AU9646198A (en)
WO (1) WO1999020620A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11633404B2 (en) 2007-08-29 2023-04-25 Senju Pharmaceutical Co., Ltd. Agent for promoting corneal endothelial cell adhesion

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094789B2 (en) 2002-07-22 2006-08-22 Asahi Kasei Pharma Corporation 5-substituted isoquinoline derivatives
US7160894B2 (en) 2003-06-06 2007-01-09 Asahi Kasei Pharma Corporation Tricyclic compound
MY139797A (en) * 2004-11-29 2009-10-30 Kowa Co (s)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1, 4-homopiperazine hydrochloride dihydrate
EP1852421B1 (en) 2005-02-25 2011-05-04 Kowa Company, Ltd. Process for production of 4-fluoroisoquinoline-5-sulfonyl halide or salt thereof
WO2006115244A1 (en) * 2005-04-25 2006-11-02 D. Western Therapeutics Institute, Inc. 4-bromoisoquinoline derivative and pharmaceutical preparation comprising the same
WO2006115245A1 (en) * 2005-04-25 2006-11-02 D. Western Therapeutics Institute, Inc. 4-ethynylisoquinoline derivative and pharmaceutical preparation comprising the same
ATE423779T1 (en) * 2005-04-25 2009-03-15 Western Therapeutics Inst Inc HIGHLY SELECTIVE RHO KINASE INHIBITOR
KR101326425B1 (en) 2005-06-21 2013-11-11 코와 가부시키가이샤 Preventive or remedy for glaucoma
EP1905452B1 (en) * 2005-07-12 2013-06-19 Kowa Company, Ltd. Agent for prevention or treatment of glaucoma
KR101149954B1 (en) 2005-08-30 2012-06-01 아사히 가세이 파마 가부시키가이샤 Sulfonamide compound
JP4800720B2 (en) * 2005-09-21 2011-10-26 興和株式会社 Ophthalmic composition
US8415372B2 (en) 2007-02-27 2013-04-09 Asahi Kasei Pharma Corporation Sulfonamide compound
WO2008105442A1 (en) 2007-02-28 2008-09-04 Asahi Kasei Pharma Corporation Sulfonamide derivative
US8232292B2 (en) 2007-07-02 2012-07-31 Asahi Kasei Pharma Corporation Sulfonamide compound and crystal thereof
WO2012026529A1 (en) 2010-08-26 2012-03-01 興和株式会社 Novel production method for isoquinoline derivatives and salts thereof
TW202126308A (en) 2011-02-04 2021-07-16 日商興和股份有限公司 Drug therapy for preventing or treating glaucoma
SI2788472T1 (en) 2011-12-06 2019-04-30 Astellas Institute For Regenerative Medicine Method of directed differentiation producing corneal endothelial cells
US20150044178A1 (en) 2011-12-28 2015-02-12 Kyoto Prefectural Public University Corporation Normalization of culture of corneal endothelial cells
EP3626245B1 (en) 2013-04-24 2021-05-05 Kyushu University, National University Corporation Therapeutic agent for eyeground disease
JP6548576B2 (en) 2013-07-30 2019-07-24 京都府公立大学法人 Corneal endothelial cell marker
JPWO2015064768A1 (en) 2013-10-31 2017-03-09 京都府公立大学法人 Drugs for diseases related to endoplasmic reticulum cell death in corneal endothelium
JP6704721B2 (en) * 2014-12-12 2020-06-03 興和株式会社 Aqueous composition
EP4218773A1 (en) 2016-02-15 2023-08-02 Kyoto Prefectural Public University Corporation Human functional corneal endothelial cell and application thereof
CN107216311B (en) * 2016-03-21 2019-09-03 山东诚创医药技术开发有限公司 (s) -4- [(4- fluoro isoquinolin -5- base) sulfonyl] -3- methyl-1, the refining methd of 4- Diazesuberane hydrochloride
CN106496189A (en) * 2016-10-10 2017-03-15 江苏礼华生物技术有限公司 Hydrochloric acid Ripasudil crystal formations
EP3710008A4 (en) 2017-11-14 2021-08-25 The Schepens Eye Research Institute, Inc. Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition
CA3110661A1 (en) 2018-08-29 2020-03-05 University Of Massachusetts Inhibition of protein kinases to treat friedreich ataxia
WO2020045642A1 (en) 2018-08-31 2020-03-05 学校法人同志社 Composition and method for preserving or culturing ocular cells
KR20210069640A (en) 2018-10-02 2021-06-11 학교법인 도시샤 Methods and Vessels for Preserving Corneal Endothelial Cells
CN111116555B (en) * 2018-10-30 2023-06-02 北京盈科瑞创新药物研究有限公司 Rho kinase inhibitor and preparation method and application thereof
CA3173725A1 (en) 2020-02-27 2021-09-02 Kyoto Prefectural Public University Corporation Functional human corneal endothelial cells and application thereof
CN111909088B (en) * 2020-08-04 2022-03-01 浙江工业大学 Method for preparing isoquinoline hydrochloride intermediate and Rho kinase inhibitor by using BTC/Ph3PO chloro-system
KR20240005837A (en) 2021-05-03 2024-01-12 아스텔라스 인스티튜트 포 리제너러티브 메디슨 Method for generating mature corneal endothelial cells
JPWO2023085369A1 (en) 2021-11-11 2023-05-19

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1210521A (en) * 1996-02-02 1999-03-10 日本新药株式会社 Isoquinoline derivatives and drugs

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11633404B2 (en) 2007-08-29 2023-04-25 Senju Pharmaceutical Co., Ltd. Agent for promoting corneal endothelial cell adhesion
US11839618B2 (en) 2007-08-29 2023-12-12 Senju Pharmaceutical Co., Ltd. Agent for promoting corneal endothelial cell adhesion

Also Published As

Publication number Publication date
JP4316794B2 (en) 2009-08-19
WO1999020620A1 (en) 1999-04-29

Similar Documents

Publication Publication Date Title
AU9646198A (en) Isoquinoline derivative and drug
AU8127998A (en) Quinoline compounds and medicinal uses thereof
PL340337A1 (en) Drugs
AU2505795A (en) 1-arylpyrimidine derivatives and pharmaceutical use thereof
AU9790198A (en) Compounds and methods
AU4892897A (en) Phospholipid drug derivatives
PL328399A1 (en) Drug administration aid
AU4721897A (en) Tetrahydroisoquinoline derivatives
AU5387898A (en) Pharmaceutical agents
AU1411499A (en) Para-aminomethylaryl carboxamide derivatives
HUP9904335A3 (en) Arylpiperidinol and arylpiperidine derivatives and drugs containing the same
AU9781998A (en) Huchordin and uses thereof
AU5880498A (en) New benzolactam derivatives and medicinal compositions containing the same
AU4204697A (en) Tetrahydroisoquinoline derivatives and their pharmaceutical use
NZ332309A (en) Alkylamino-benzothiazole and -benzoxazole derivatives and medicaments
AU4161797A (en) Benzoperimidine-carboxylic acids and derivatives thereof
AU1409100A (en) Drugs
AU1415099A (en) 4-substituted-4-piperidine carboxamide derivatives
AU5923998A (en) 2-benzoylamino-3-phenylpropenamide derivatives and methods of using the same
AU7449198A (en) Phthalimide derivatives and pharmaceutical containing said derivatives
HK1036273A1 (en) Pyridine derivative and pharmaceutical containing the same
AU732214C (en) Biphenyl derivatives and drug composition
AU3107497A (en) Asialotrisaccharide moranoline derivatives and drugs
AU691677B2 (en) Tetrahydroisoquinoline derivative and medicinal preparation containing the same
AU1698899A (en) N-acetylserotonin derivatives and uses thereof

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase