AU9211098A - Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents - Google Patents

Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents

Info

Publication number
AU9211098A
AU9211098A AU92110/98A AU9211098A AU9211098A AU 9211098 A AU9211098 A AU 9211098A AU 92110/98 A AU92110/98 A AU 92110/98A AU 9211098 A AU9211098 A AU 9211098A AU 9211098 A AU9211098 A AU 9211098A
Authority
AU
Australia
Prior art keywords
thiourea
useful
cholesterol levels
increasing hdl
atherosclerotic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU92110/98A
Inventor
Amedeo Arturo Failli
Jay Scott Shumsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of AU9211098A publication Critical patent/AU9211098A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU92110/98A 1997-09-03 1998-08-31 Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents Abandoned AU9211098A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92264897A 1997-09-03 1997-09-03
US08922648 1997-09-03
PCT/US1998/017955 WO1999011621A2 (en) 1997-09-03 1998-08-31 Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents

Publications (1)

Publication Number Publication Date
AU9211098A true AU9211098A (en) 1999-03-22

Family

ID=25447377

Family Applications (1)

Application Number Title Priority Date Filing Date
AU92110/98A Abandoned AU9211098A (en) 1997-09-03 1998-08-31 Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents

Country Status (4)

Country Link
AR (1) AR017047A1 (en)
AU (1) AU9211098A (en)
WO (1) WO1999011621A2 (en)
ZA (1) ZA987970B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA76977C2 (en) * 2001-03-02 2006-10-16 Icos Corp Aryl- and heteroaryl substituted chk1 inhibitors and their use as radiosensitizers and chemosensitizers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
JPS5481275A (en) * 1977-10-08 1979-06-28 Toshihiko Okamoto Nn*22chlorr44pyridyl*ureas*manufacture and vegetable growth regulating agent
US4387106A (en) * 1982-01-26 1983-06-07 American Cyanamid Company Method of treating atherosclerosis with di(aralkyl)ureas and di(aralkyl)thioureas
DD223445A1 (en) * 1984-03-18 1985-06-12 Neubauer T Paedagog Hochschule PROCESS FOR THE PREPARATION OF THIROUS FUEL DERIVATIVES
HUT62558A (en) * 1991-07-01 1993-05-28 Sandoz Ag Process for producing n-phenylthiourea derivaties and pharmaceutical compositions comprising same
JPH0612447A (en) * 1992-03-31 1994-01-21 Toshiba Corp Summary sentence preparing device
WO1996018617A1 (en) * 1994-12-12 1996-06-20 Merck & Co., Inc. Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase
US5773459A (en) * 1995-06-07 1998-06-30 Sugen, Inc. Urea- and thiourea-type compounds

Also Published As

Publication number Publication date
AR017047A1 (en) 2001-08-22
WO1999011621A3 (en) 1999-07-01
WO1999011621A2 (en) 1999-03-11
ZA987970B (en) 2000-05-31

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase