AU4766096A - Anti-obesity proteins - Google Patents

Anti-obesity proteins

Info

Publication number
AU4766096A
AU4766096A AU47660/96A AU4766096A AU4766096A AU 4766096 A AU4766096 A AU 4766096A AU 47660/96 A AU47660/96 A AU 47660/96A AU 4766096 A AU4766096 A AU 4766096A AU 4766096 A AU4766096 A AU 4766096A
Authority
AU
Australia
Prior art keywords
obesity proteins
obesity
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU47660/96A
Inventor
Margaret B Basinski
Richard D. Dimarchi
David B Flora
William F. Heath Jr.
James A Hoffmann
Brigitte E Schoner
James E Shields
David L Smiley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/381,034 external-priority patent/US5532336A/en
Priority claimed from US08/381,054 external-priority patent/US5569743A/en
Priority claimed from US08/381,370 external-priority patent/US5525705A/en
Priority claimed from US08/381,050 external-priority patent/US5563244A/en
Priority claimed from US08/381,037 external-priority patent/US5563243A/en
Priority claimed from US08/381,049 external-priority patent/US5574133A/en
Priority claimed from US08/381,057 external-priority patent/US5580954A/en
Priority claimed from US08/381,040 external-priority patent/US5552522A/en
Priority claimed from US08/381,666 external-priority patent/US5521283A/en
Priority claimed from US08/381,041 external-priority patent/US5567678A/en
Priority claimed from US08/381,163 external-priority patent/US5563245A/en
Priority claimed from US08/384,492 external-priority patent/US5594104A/en
Priority claimed from US08/383,649 external-priority patent/US5567803A/en
Priority claimed from US08/383,650 external-priority patent/US5691309A/en
Priority claimed from US08/383,632 external-priority patent/US5569744A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU4766096A publication Critical patent/AU4766096A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU47660/96A 1995-01-31 1996-01-29 Anti-obesity proteins Abandoned AU4766096A (en)

Applications Claiming Priority (39)

Application Number Priority Date Filing Date Title
US381266 1982-05-24
US381057 1989-07-17
US381040 1989-07-17
US383632 1989-07-24
US38145195A 1995-01-31 1995-01-31
US38104795A 1995-01-31 1995-01-31
US38126695A 1995-01-31 1995-01-31
US38124795A 1995-01-31 1995-01-31
US381163 1995-01-31
US08/381,054 US5569743A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US08/381,163 US5563245A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US08/381,037 US5563243A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US381034 1995-01-31
US381247 1995-01-31
US381049 1995-01-31
US381037 1995-01-31
US381050 1995-01-31
US08/381,049 US5574133A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US08/381,057 US5580954A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US08/381,040 US5552522A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US08/381,034 US5532336A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US381451 1995-01-31
US08/381,370 US5525705A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US381047 1995-01-31
US381370 1995-01-31
US08/381,050 US5563244A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US08/381,041 US5567678A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US381666 1995-01-31
US381041 1995-01-31
US381054 1995-01-31
US08/381,666 US5521283A (en) 1995-01-31 1995-01-31 Anti-obesity proteins
US08/384,492 US5594104A (en) 1995-01-31 1995-02-06 Anti-obesity proteins
US384492 1995-02-06
US383649 1995-02-06
US08/383,649 US5567803A (en) 1995-01-31 1995-02-06 Anti-obesity proteins
US08/383,650 US5691309A (en) 1995-01-31 1995-02-06 Anti-obesity proteins
US08/383,632 US5569744A (en) 1995-01-31 1995-02-06 Anti-obesity proteins
PCT/US1996/000947 WO1996023514A1 (en) 1995-01-31 1996-01-29 Anti-obesity proteins
US383650 2009-03-27

Publications (1)

Publication Number Publication Date
AU4766096A true AU4766096A (en) 1996-08-21

Family

ID=27586325

Family Applications (1)

Application Number Title Priority Date Filing Date
AU47660/96A Abandoned AU4766096A (en) 1995-01-31 1996-01-29 Anti-obesity proteins

Country Status (5)

Country Link
EP (1) EP0836620A1 (en)
JP (1) JPH11501297A (en)
AU (1) AU4766096A (en)
CA (1) CA2211656A1 (en)
WO (1) WO1996023514A1 (en)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
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US6429290B1 (en) 1994-08-17 2002-08-06 The Rockefeller University OB polypeptides, modified forms and derivatives
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
GB9509164D0 (en) * 1995-05-05 1995-06-28 Smithkline Beecham Plc Novel compounds
WO1997016550A1 (en) * 1995-11-02 1997-05-09 Bristol-Myers Squibb Company Polypeptide fragments derived from the obese gene product
EP0902623A1 (en) * 1996-04-23 1999-03-24 Novo Nordisk A/S Animal feed additives
AU3337297A (en) * 1996-06-06 1998-01-05 Smithkline Beecham Plc Fragments of leptin (ob protein)
WO1998016545A1 (en) * 1996-10-11 1998-04-23 Eli Lilly And Company Therapeutic proteins
US6420339B1 (en) 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
DE60237100D1 (en) 2001-10-22 2010-09-02 Amgen Inc USE OF LEPTIN FOR THE TREATMENT OF LIPOATROPR PREDICTIVE POSITION AGAINST TREATMENT
US7105526B2 (en) 2002-06-28 2006-09-12 Banyu Pharmaceuticals Co., Ltd. Benzimidazole derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP4765627B2 (en) 2003-09-22 2011-09-07 Ｍｓｄ株式会社 Novel piperidine derivatives
EP1734963A4 (en) 2004-04-02 2008-06-18 Merck & Co Inc Method of treating men with metabolic and anthropometric disorders
US7737155B2 (en) 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
EP1892241B1 (en) 2005-05-30 2016-03-30 Msd K.K. Novel piperidine derivative
EP1916239A4 (en) 2005-08-10 2009-10-21 Banyu Pharma Co Ltd Pyridone compound
JPWO2007024004A1 (en) 2005-08-24 2009-03-05 萬有製薬株式会社 Phenylpyridone derivatives
US8227408B2 (en) 2005-09-07 2012-07-24 Neurotez, Inc. Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology
US20090264426A1 (en) 2005-09-07 2009-10-22 Shunji Sakuraba Bicyclic aromatic substituted pyridone derivative
CN101277960A (en) 2005-09-29 2008-10-01 默克公司 Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
CA2625416A1 (en) 2005-10-21 2007-04-26 Novartis Ag Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent
AU2006307046A1 (en) 2005-10-27 2007-05-03 Msd K.K. Novel benzoxathiin derivative
RU2428423C2 (en) 2005-11-10 2011-09-10 Баниу Фармасьютикал Ко., Лтд. Aza-substituted spiro-derivatives
EP2083831B1 (en) 2006-09-22 2013-12-25 Merck Sharp & Dohme Corp. Method of treatment using fatty acid synthesis inhibitors
AU2007301126A1 (en) 2006-09-28 2008-04-03 Banyu Pharmaceutical Co., Ltd. Diaryl ketimine derivative
WO2008120653A1 (en) 2007-04-02 2008-10-09 Banyu Pharmaceutical Co., Ltd. Indoledione derivative
ES2559319T3 (en) 2007-06-04 2016-02-11 Synergy Pharmaceuticals Inc. Guanylate cliclas agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2264026A4 (en) 2008-03-06 2012-03-28 Msd Kk Alkylaminopyridine derivative
CA2717384A1 (en) 2008-03-28 2009-10-01 Banyu Pharmaceutical Co., Ltd. Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism
KR20110028457A (en) 2008-05-21 2011-03-18 뉴로테즈 인코포레이티드 Methods for treating progressive cognitive disorders related to neurofibrillary tangles
JP2011522828A (en) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer, and other disorders
US20110071129A1 (en) 2008-06-19 2011-03-24 Makoto Ando Spirodiamine-diaryl ketoxime derivative
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
CA2731358A1 (en) 2008-07-30 2010-02-04 Banyu Pharmaceutical Co., Ltd. 5/5-or 5/6-membered condensed ring cycloalkylamine derivative
CA2741125A1 (en) 2008-10-22 2010-04-29 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
JP5557845B2 (en) 2008-10-31 2014-07-23 メルク・シャープ・アンド・ドーム・コーポレーション Novel cyclic benzimidazole derivatives useful as antidiabetic agents
WO2010054017A1 (en) 2008-11-04 2010-05-14 Nikolaos Tezapsidis Leptin compositions and methods for treating progressive cognitive function disorders resulting from accumulation of neurofibrillary tangles and amlyoid beta
US20110243940A1 (en) 2008-12-16 2011-10-06 Schering Corporation Bicyclic pyranone derivatives and methods of use thereof
WO2010075068A1 (en) 2008-12-16 2010-07-01 Schering Corporation Pyridopyrimidine derivatives and methods of use thereof
US20120071401A1 (en) 2009-04-10 2012-03-22 Amylin Pharamaceuticals, Inc. Amylin agonist compounds for estrogen-deficient mammals
AU2011218830B2 (en) 2010-02-25 2014-07-24 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP3241558B1 (en) 2010-09-28 2021-03-03 Aegerion Pharmaceuticals, Inc. Highly soluble leptins
EA201690035A1 (en) 2011-02-25 2016-05-31 Мерк Шарп Энд Домэ Корп. NEW CYCLIC DERIVATIVES OF AZABENZIMIDAZOLE, USED AS ANTI-DIABETIC AGENTS
AU2013296470B2 (en) 2012-08-02 2016-03-17 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
CN104994848A (en) 2013-02-22 2015-10-21 默沙东公司 Antidiabetic bicyclic compounds
EP2970119B1 (en) 2013-03-14 2021-11-03 Merck Sharp & Dohme Corp. Novel indole derivatives useful as anti-diabetic agents
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
PT3004138T (en) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2015051496A1 (en) 2013-10-08 2015-04-16 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
RU2021109549A (en) 2014-08-29 2021-05-13 Тес Фарма С.Р.Л. Α-AMINO-β-CARBOXYMUCONATE INHIBITORS of ε-SEMIALDEHYDE-DECARBOXYLASE
WO2018069532A1 (en) 2016-10-14 2018-04-19 Tes Pharma S.R.L. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
US11072602B2 (en) 2016-12-06 2021-07-27 Merck Sharp & Dohme Corp. Antidiabetic heterocyclic compounds
US10968232B2 (en) 2016-12-20 2021-04-06 Merck Sharp & Dohme Corp. Antidiabetic spirochroman compounds
CN113302189A (en) 2018-11-20 2021-08-24 Tes制药有限责任公司 Inhibitors of alpha-amino-beta-carboxyadipimic acid semialdehyde decarboxylating enzyme

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4626549A (en) * 1974-01-10 1986-12-02 Eli Lilly And Company Treatment of obesity with aryloxyphenylpropylamines

Also Published As

Publication number Publication date
EP0836620A1 (en) 1998-04-22
CA2211656A1 (en) 1996-08-08
WO1996023514A1 (en) 1996-08-08
JPH11501297A (en) 1999-02-02

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