AU2002228891A1 - Cytoprotective estrogen derivatives - Google Patents

Cytoprotective estrogen derivatives

Info

Publication number
AU2002228891A1
AU2002228891A1 AU2002228891A AU2889102A AU2002228891A1 AU 2002228891 A1 AU2002228891 A1 AU 2002228891A1 AU 2002228891 A AU2002228891 A AU 2002228891A AU 2889102 A AU2889102 A AU 2889102A AU 2002228891 A1 AU2002228891 A1 AU 2002228891A1
Authority
AU
Australia
Prior art keywords
cytoprotective
estrogen derivatives
estrogen
derivatives
cytoprotective estrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002228891A
Inventor
Douglas F. Covey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Washington University in St Louis WUSTL
Original Assignee
University of Washington
Washington University in St Louis WUSTL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington, Washington University in St Louis WUSTL filed Critical University of Washington
Publication of AU2002228891A1 publication Critical patent/AU2002228891A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002228891A 2000-11-17 2001-11-05 Cytoprotective estrogen derivatives Abandoned AU2002228891A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24958000P 2000-11-17 2000-11-17
US60/249,580 2000-11-17
PCT/US2001/047262 WO2002040032A2 (en) 2000-11-17 2001-11-05 Cytoprotective estrogen derivatives

Publications (1)

Publication Number Publication Date
AU2002228891A1 true AU2002228891A1 (en) 2002-05-27

Family

ID=22944106

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002228891A Abandoned AU2002228891A1 (en) 2000-11-17 2001-11-05 Cytoprotective estrogen derivatives

Country Status (3)

Country Link
US (1) US20020132802A1 (en)
AU (1) AU2002228891A1 (en)
WO (1) WO2002040032A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2292239A3 (en) 2003-04-18 2011-03-30 Advanced Medicine Research Institute Remedies for diseases to be applied to eye
EP1749017A2 (en) * 2004-05-27 2007-02-07 MIGENIX Corp. Compounds and methods for cytoprotection
US10055727B2 (en) 2012-11-05 2018-08-21 Mfoundry, Inc. Cloud-based systems and methods for providing consumer financial data

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1509931A (en) * 1966-04-29 1968-01-19 Roussel Uclaf Process for the preparation of optically active ketone compounds and products thereof
US4330540A (en) * 1981-01-29 1982-05-18 Akzo N.V. Ent-16-amino-17-hydroxy-oestra-1,3,5(10)-trienes and derivatives thereof, and pharmaceutical compositions
US4617298A (en) * 1985-10-22 1986-10-14 University Of Florida Method and compositions for weight control
US4786647A (en) * 1986-06-30 1988-11-22 University Of Florida Method for eliciting anxiolysis
IL110309A0 (en) * 1993-07-15 1994-10-21 Univ Kentucky Res Found A method of protecting against neuron loss
US5877169A (en) * 1993-11-05 1999-03-02 University Of Florida Research Foundation, Inc. Methods of treatment of ischemic damage
US5554601A (en) * 1993-11-05 1996-09-10 University Of Florida Methods for neuroprotection
US5859001A (en) * 1996-01-11 1999-01-12 University Of Florida Research Foundation, Inc. Neuroprotective effects of polycyclic phenolic compounds
US6197833B1 (en) * 1995-07-24 2001-03-06 Apollo Biopharmaceutics, Inc. Neuroprotective effects of polycyclic phenolic compounds
DE4338316A1 (en) * 1993-11-10 1995-05-11 Jenapharm Gmbh New steroids with radicallyophilic substituents, process for their preparation and medicaments containing these compounds
DE4338314C1 (en) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmaceutical preparations for the prophylaxis and therapy of radical-mediated cell damage
FR2717690B1 (en) * 1994-03-24 1996-04-26 Roussel Uclaf Application of aromatic steroids 3 substituted by an aminoalkoxy substituted for obtaining a medicament for controlling sterility, especially male sterility.
FR2718138B1 (en) * 1994-04-01 1996-04-26 Roussel Uclaf New steroids comprising in position 20 an amino-substituted chain, process and intermediates for preparation, application as medicaments and pharmaceutical compositions containing them.
US5395831A (en) * 1994-04-08 1995-03-07 American Home Products Corporation Treating cardiac disorders with Δ9(11)-dehydro-8-isoestrone
DE4429397C2 (en) * 1994-08-09 2003-11-20 Jenapharm Gmbh Estra-1,3,5 (10) -triene derivatives, processes for their preparation and pharmaceutical compositions containing these compounds
EP0841906A1 (en) * 1995-07-24 1998-05-20 University Of Florida Research Foundation, Inc. Use of non-estrogen polycyclic phenol compounds for the manufacture of a medicament for conferring neuroprotection to cells
ATE262915T1 (en) * 1997-01-16 2004-04-15 Univ Florida COMPOSITIONS FOR ENHANCEMENT OF CYTOPROTECTIVE ACTION OF POLYCYCLIC PHENOL COMPOUNDS THROUGH SYNERGISTIC INTERACTION OF ANTIOXIDANTS
DE19723794A1 (en) * 1997-06-06 1998-12-10 Jenapharm Gmbh Non-estrogenic derivatives of estradiol with antioxidant activity
US6245756B1 (en) * 1998-02-27 2001-06-12 Jenapharm Gmbh & Co. Kg Pharmaceutical preparations for treatment of estrogen deficiency in the central nervous system
DE19917930A1 (en) * 1999-04-15 2000-10-19 Schering Ag Treating estrogen deficiency associated disorders, e.g. menopausal problems, osteoporosis, neoplasia or neurodegenerative disease, using new or known ent-steroids having bone-selective estrogenic activity
US6265147B1 (en) * 1999-12-01 2001-07-24 The Board Of Trustees Of The Leland Stanford Junior University Method of screening for neuroprotective agents

Also Published As

Publication number Publication date
US20020132802A1 (en) 2002-09-19
WO2002040032A2 (en) 2002-05-23
WO2002040032A3 (en) 2003-08-28

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