AU2002220241A1 - Parb inhibitors - Google Patents

Parb inhibitors

Info

Publication number
AU2002220241A1
AU2002220241A1 AU2002220241A AU2024102A AU2002220241A1 AU 2002220241 A1 AU2002220241 A1 AU 2002220241A1 AU 2002220241 A AU2002220241 A AU 2002220241A AU 2024102 A AU2024102 A AU 2024102A AU 2002220241 A1 AU2002220241 A1 AU 2002220241A1
Authority
AU
Australia
Prior art keywords
parb
inhibitors
parb inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002220241A
Inventor
Teri Melese
Edward L Perkins
Donxu Sun
Elaine Yeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iconix Pharmaceuticals Inc
Original Assignee
Iconix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iconix Pharmaceuticals Inc filed Critical Iconix Pharmaceuticals Inc
Publication of AU2002220241A1 publication Critical patent/AU2002220241A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002220241A 2000-12-01 2001-12-03 Parb inhibitors Abandoned AU2002220241A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25081100P 2000-12-01 2000-12-01
US60/250,811 2000-12-01
PCT/US2001/046811 WO2002044157A2 (en) 2000-12-01 2001-12-03 Parb inhibitors

Publications (1)

Publication Number Publication Date
AU2002220241A1 true AU2002220241A1 (en) 2002-06-11

Family

ID=22949252

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002220241A Abandoned AU2002220241A1 (en) 2000-12-01 2001-12-03 Parb inhibitors

Country Status (2)

Country Link
AU (1) AU2002220241A1 (en)
WO (1) WO2002044157A2 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794383B2 (en) 2000-08-31 2004-09-21 Takeda Chemical Industries, Ltd. Heart muscular cell apoptosis inhibitors and remedies/preventives for heart diseases
US7151102B2 (en) 2000-10-30 2006-12-19 Kudos Pharmaceuticals Limited Phthalazinone derivatives
CA2444531A1 (en) 2001-05-08 2002-11-14 Kudos Pharmaceuticals Limited Isoquinolinone derivatives as parp inhibitors
JPWO2002094790A1 (en) * 2001-05-23 2004-09-09 三菱ウェルファーマ株式会社 Fused heterocyclic compounds and their pharmaceutical uses
ATE491703T1 (en) 2002-04-30 2011-01-15 Kudos Pharm Ltd PHTHALAZINONE DERIVATIVES
JPWO2004024694A1 (en) * 2002-09-10 2006-01-05 杏林製薬株式会社 4-substituted aryl-5-hydroxyisoquinolinone derivatives
TW200424188A (en) 2002-10-01 2004-11-16 Mitsubishi Pharma Corp Isoquinoline compound and pharmaceutical use thereof
CA2507027C (en) 2002-11-22 2012-05-08 Mitsubishi Pharma Corporation Isoquinoline compounds and medicinal use thereof
AU2003289176A1 (en) * 2002-12-05 2004-07-29 Takeda Pharmaceutical Company Limited 1,3-benzothiazinone derivatives, process for producing the same and use thereof
GB0305681D0 (en) 2003-03-12 2003-04-16 Kudos Pharm Ltd Phthalazinone derivatives
US7449464B2 (en) 2003-03-12 2008-11-11 Kudos Pharmaceuticals Limited Phthalazinone derivatives
GB0521373D0 (en) 2005-10-20 2005-11-30 Kudos Pharm Ltd Pthalazinone derivatives
TWI404716B (en) 2006-10-17 2013-08-11 Kudos Pharm Ltd Phthalazinone derivative
US20090012103A1 (en) 2007-07-05 2009-01-08 Matthew Abelman Substituted heterocyclic compounds
CA2699038A1 (en) 2007-09-14 2009-03-19 Astrazeneca Ab Phthalazinone derivatives
UY31603A1 (en) 2008-01-23 2009-08-31 DERIVATIVES OF FTALAZINONA
CN102238945B (en) 2008-10-07 2014-10-29 阿斯利康(英国)有限公司 Pharmaceutical formulation 514
US20100113461A1 (en) 2008-10-29 2010-05-06 Gilead Palo Alto, Inc. Substituted heterocyclic compounds
US20100113514A1 (en) 2008-10-30 2010-05-06 Gilead Palo Alto, Inc. Fused heterocyclic compounds as ion channel modulators
US20100125091A1 (en) 2008-11-14 2010-05-20 Gilead Palo Alto, Inc. Substituted heterocyclic compounds as ion channel modulators
CN104803986A (en) 2008-12-23 2015-07-29 哈佛大学校长及研究员协会 Small molecule inhibitors of necroptosis
EP2214020B1 (en) * 2009-01-29 2012-08-15 Bergen Teknologieverforing AS PARP-based cytochemical and histochemical detection methods and kits therefor
ES2406635B1 (en) * 2011-12-02 2014-06-11 Cartonajes Bernabeu, S.A. PALETIZING SYSTEM FOR PACKING FEEDING LINES.
WO2014087165A1 (en) * 2012-12-06 2014-06-12 University Of Bath Tankyrase inhibitors
WO2014145022A1 (en) 2013-03-15 2014-09-18 President And Fellows Of Harvard College Hybrid necroptosis inhibitors
ES2879434T3 (en) 2015-07-23 2021-11-22 Inst Curie Use of a combination of Dbait molecule and PARP inhibitors for cancer treatment
GB201519573D0 (en) 2015-11-05 2015-12-23 King S College London Combination
WO2018162439A1 (en) 2017-03-08 2018-09-13 Onxeo New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule
US20200407720A1 (en) 2018-03-13 2020-12-31 Onxeo A dbait molecule against acquired resistance in the treatment of cancer
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2108066T3 (en) * 1991-10-31 1997-12-16 Asta Medica Ag NEW PHTHALAZINES THAT IN POSITION 1 CONTAIN AN ETER GROUPING, AND PROCEDURE FOR THEIR PREPARATION.
GB9702701D0 (en) * 1997-02-01 1997-04-02 Univ Newcastle Ventures Ltd Quinazolinone compounds
US6197785B1 (en) * 1997-09-03 2001-03-06 Guilford Pharmaceuticals Inc. Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity
ITMI981670A1 (en) * 1998-07-21 2000-01-21 Zambon Spa PHTHALAZINIC DERIVATIVES INHIBITORS OF PHOSPHODIESTERASE 4
RU2167659C1 (en) * 2000-08-02 2001-05-27 Закрытое акционерное общество "Центр современной медицины "Медикор" Method of correction of immune system of living body

Also Published As

Publication number Publication date
WO2002044157A3 (en) 2002-12-27
WO2002044157A2 (en) 2002-06-06

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