AU2002219127A1 - Process for the production of ceftifur sodium salt - Google Patents

Process for the production of ceftifur sodium salt

Info

Publication number
AU2002219127A1
AU2002219127A1 AU2002219127A AU1912702A AU2002219127A1 AU 2002219127 A1 AU2002219127 A1 AU 2002219127A1 AU 2002219127 A AU2002219127 A AU 2002219127A AU 1912702 A AU1912702 A AU 1912702A AU 2002219127 A1 AU2002219127 A1 AU 2002219127A1
Authority
AU
Australia
Prior art keywords
sodium salt
ceftifur
production
formula
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002219127A
Inventor
Andreas Berger
Martin Decristorforo
Johannes Ludescher
Herbert Schleich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz GmbH
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Publication of AU2002219127A1 publication Critical patent/AU2002219127A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Process for preparing ceftiofur having formula I:in the form of the sodium salt.
AU2002219127A 2000-11-22 2001-11-20 Process for the production of ceftifur sodium salt Abandoned AU2002219127A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25270700P 2000-11-22 2000-11-22
US60/252,707 2000-11-22
PCT/EP2001/013443 WO2002042266A2 (en) 2000-11-22 2001-11-20 Process for the production of ceftifur sodium salt

Publications (1)

Publication Number Publication Date
AU2002219127A1 true AU2002219127A1 (en) 2002-06-03

Family

ID=22957174

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002219127A Abandoned AU2002219127A1 (en) 2000-11-22 2001-11-20 Process for the production of ceftifur sodium salt

Country Status (11)

Country Link
US (1) US6504026B2 (en)
EP (1) EP1343790B1 (en)
JP (1) JP4319835B2 (en)
KR (1) KR100870885B1 (en)
AT (1) ATE318825T1 (en)
AU (1) AU2002219127A1 (en)
CA (1) CA2427199C (en)
DE (1) DE60117620T2 (en)
ES (1) ES2258569T3 (en)
TW (1) TWI246513B (en)
WO (1) WO2002042266A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555679B2 (en) 2001-10-03 2003-04-29 Orchid Chemicals & Pharmaceuticals Ltd. Method for preparation of ceftiofur sodium from its hydrohalide salts
JP2006507290A (en) * 2002-10-29 2006-03-02 ルピン リミティド Method for producing ceftiofur
NZ566790A (en) * 2005-10-12 2011-03-31 Orchid Chemicals & Pharm Ltd Crystalline sodium salt of cephalosporin antibiotic
US8470809B2 (en) * 2005-10-12 2013-06-25 Orchid Chemicals & Pharmaceuticals Limited Crystalline sodium salt of cephalosporin antibiotic
US8431562B2 (en) * 2008-08-22 2013-04-30 Orchid Chemicals & Pharmaceuticals Limited Crystalline sodium salt of cephalosporin antibiotic
KR101699539B1 (en) * 2015-12-30 2017-02-13 (주)솔레이어 Nano filteration module and condensation method using the same
CN115772179A (en) * 2022-12-09 2023-03-10 山东鑫泉医药有限公司 Recrystallization method of ceftiofur sodium

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902683A (en) * 1984-10-25 1990-02-20 The Upjohn Company Crystalline cephalosporin hydrohalide salts
JPH0749432B2 (en) 1985-08-12 1995-05-31 ジ・アップジョン・カンパニ− Conversion of cephalosporin hydrohalides to alkali metal salts
US4877782A (en) * 1988-02-16 1989-10-31 The Upjohn Company Zinc ceftiofur complexes
IL95561A0 (en) 1990-09-02 1991-06-30 Weizmann Kiryat Membrane Prod Method for the purification and concentration of biologically active materials
JP2919112B2 (en) * 1991-05-13 1999-07-12 武田薬品工業株式会社 Cephalosporin injection and production method thereof
TW293821B (en) 1993-09-27 1996-12-21 Ind Tech Res Inst Process for preparing alkali salts of cephalosporin C
US5491259A (en) 1994-09-13 1996-02-13 The Dow Chemical Company Process to produce aminocarboxylic acids containing low residual salt
ES2105988B1 (en) 1996-03-15 1998-07-01 Antibioticos Sa PROCEDURE TO PURIFY 7-SUBSTITUTED-AMINO-DESACETOXI-CEPHALOSPORINS THROUGH THE USE OF FILTRATION MEMBRANES.
IT1283641B1 (en) 1996-07-30 1998-04-23 Ribbon Srl PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINE
SI1071744T1 (en) 1998-04-14 2003-12-31 Dsm Ip Assets B.V. Membrane filtration
DE19839209A1 (en) 1998-08-28 2000-03-02 Fraunhofer Ges Forschung Process for obtaining solid substances from solutions
KR100355115B1 (en) * 1999-01-14 2002-11-22 주식회사 엘지씨아이 New cephem compouns for preparation of ceftiofur
JP3737642B2 (en) * 1999-01-18 2006-01-18 武田薬品工業株式会社 Cephalosporin injection and method for producing the same
US6458949B1 (en) * 2000-08-14 2002-10-01 Aurobindo Pharma Limited Ceftiofur, its intermediate and a process for the preparation of the same

Also Published As

Publication number Publication date
CA2427199C (en) 2009-02-10
WO2002042266A2 (en) 2002-05-30
JP4319835B2 (en) 2009-08-26
US6504026B2 (en) 2003-01-07
DE60117620T2 (en) 2006-10-12
EP1343790A2 (en) 2003-09-17
KR100870885B1 (en) 2008-11-28
WO2002042266A3 (en) 2002-08-15
CA2427199A1 (en) 2002-05-30
DE60117620D1 (en) 2006-04-27
TWI246513B (en) 2006-01-01
ES2258569T3 (en) 2006-09-01
EP1343790B1 (en) 2006-03-01
ATE318825T1 (en) 2006-03-15
JP2004514667A (en) 2004-05-20
US20020082248A1 (en) 2002-06-27
KR20030070014A (en) 2003-08-27

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