ATE491722T1 - Herstellung und reinigung von il-29 - Google Patents

Herstellung und reinigung von il-29

Info

Publication number
ATE491722T1
ATE491722T1 AT06816409T AT06816409T ATE491722T1 AT E491722 T1 ATE491722 T1 AT E491722T1 AT 06816409 T AT06816409 T AT 06816409T AT 06816409 T AT06816409 T AT 06816409T AT E491722 T1 ATE491722 T1 AT E491722T1
Authority
AT
Austria
Prior art keywords
methods
production
purification
coli
vectors
Prior art date
Application number
AT06816409T
Other languages
English (en)
Inventor
Bruce Zamost
Geoffrey Lee
Robert Dedinsky
Original Assignee
Zymogenetics L L C
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics L L C, Bristol Myers Squibb Co filed Critical Zymogenetics L L C
Application granted granted Critical
Publication of ATE491722T1 publication Critical patent/ATE491722T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06816409T 2005-10-04 2006-10-04 Herstellung und reinigung von il-29 ATE491722T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72354405P 2005-10-04 2005-10-04
PCT/US2006/039139 WO2007041713A1 (en) 2005-10-04 2006-10-04 Production and purification of il-29

Publications (1)

Publication Number Publication Date
ATE491722T1 true ATE491722T1 (de) 2011-01-15

Family

ID=37603659

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06816409T ATE491722T1 (de) 2005-10-04 2006-10-04 Herstellung und reinigung von il-29

Country Status (15)

Country Link
US (6) US20080096252A1 (de)
EP (1) EP1931704B1 (de)
JP (3) JP5364375B2 (de)
AT (1) ATE491722T1 (de)
AU (1) AU2006299339B2 (de)
CA (1) CA2625208A1 (de)
CY (1) CY1112323T1 (de)
DE (1) DE602006018969D1 (de)
DK (1) DK1931704T3 (de)
ES (1) ES2357152T3 (de)
IL (2) IL189994A (de)
PL (1) PL1931704T3 (de)
PT (1) PT1931704E (de)
SI (1) SI1931704T1 (de)
WO (1) WO2007041713A1 (de)

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US8691205B2 (en) 2008-12-17 2014-04-08 Merck Sharp & Dohme Corporation Mono- and di-PEG IL-10 production; and uses
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RU2549710C2 (ru) * 2012-06-29 2015-04-27 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа
JP6086378B2 (ja) * 2012-11-30 2017-03-01 国立大学法人お茶の水女子大学 組み換えヒト膵臓リパーゼの調製方法
CN104045704B (zh) * 2013-03-11 2016-08-10 中国医学科学院基础医学研究所 PEG化重组人IFN-λ1、其制备方法和用途
CN105209054A (zh) 2013-04-18 2015-12-30 阿尔莫生物科技股份有限公司 使用白细胞介素-10治疗疾病和病症的方法
AU2014281828B2 (en) 2013-06-17 2019-05-09 Armo Biosciences, Inc. Method for assessing protein identity and stability
US20160159853A1 (en) * 2013-07-19 2016-06-09 Biogenomics Limited Apparatus for refolding of recombinant proteins
JP6509867B2 (ja) 2013-08-30 2019-05-08 アルモ・バイオサイエンシーズ・インコーポレイテッド 疾患及び障害を治療するためにインターロイキン−10を使用する方法
JP6660297B2 (ja) 2013-11-11 2020-03-11 アルモ・バイオサイエンシーズ・インコーポレイテッド 疾患及び障害を処置するためのインターロイキン−10の使用方法
JP6730926B2 (ja) * 2014-01-08 2020-07-29 プロージット ソウル バイオテクノロジー (ベイジン) カンパニー リミテッド 融合ポリペプチドおよび使用方法
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2015187295A2 (en) 2014-06-02 2015-12-10 Armo Biosciences, Inc. Methods of lowering serum cholesterol
JP2017536098A (ja) 2014-10-14 2017-12-07 アルモ・バイオサイエンシーズ・インコーポレイテッド インターロイキン−15組成物及びその使用
ES2941234T3 (es) 2014-10-22 2023-05-19 Armo Biosciences Inc Métodos de uso de la interleucina-10 para el tratamiento de enfermedades y trastornos
EP3237441A4 (de) * 2014-12-23 2018-06-06 Armo Biosciences, Inc. Verfahren zur verbesserung des ertrags in der produktion rekombinanter proteine
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
WO2016172342A1 (en) 2015-04-21 2016-10-27 Eiger Biopharmaceuticals, Inc. Pharmaceutical compositions comprising lonafarnib and ritonavir
CN107847583A (zh) 2015-05-28 2018-03-27 阿尔莫生物科技股份有限公司 用于治疗癌症的聚乙二醇化白细胞介素‑10
KR20180038553A (ko) 2015-08-25 2018-04-16 아르모 바이오사이언시스 인코포레이티드 질환 및 장애를 치료하기 위한 인터류킨-10을 사용하는 방법
US10953072B2 (en) 2016-02-19 2021-03-23 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection with interferon lambda
JP7073363B2 (ja) * 2016-11-07 2022-05-23 シージェン インコーポレイテッド 工学的に操作されたシステインキャップの分配
EP3927733A4 (de) 2019-02-24 2022-07-06 Oncosimis Biotech Private Limited Verfahren zur kontinuierlichen herstellung von rekombinantem glp-1-peptid durch bakterien

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EP0626448A3 (de) * 1993-05-26 1998-01-14 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verfahren zur Herstellung und Reinigung von alpha-Interferon
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CZ299516B6 (cs) * 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
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US7038032B2 (en) * 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
AU2003286624B2 (en) * 2002-10-23 2008-11-13 Bristol-Myers Squibb Company Methods for treating viral infection using IL-28 and IL-29
MXPA05006117A (es) * 2002-12-13 2005-09-30 Zymogenetics Inc Produccion de il-21 en hospederos procarioticos.
WO2005023862A2 (en) * 2003-08-07 2005-03-17 Zymogenetics, Inc. Homogeneous preparations of il-28 and il-29
US20050244423A1 (en) * 2004-04-02 2005-11-03 Klucher Kevin M Methods for treating viral infection using IL-28 and IL-29 cysteine mutants
US7351689B2 (en) * 2004-07-29 2008-04-01 Zymogenetics, Inc. Use of IL-28 and IL-29 to treat cancer and autoimmune disorders
CN1305902C (zh) * 2004-11-25 2007-03-21 汕头大学医学院 一种人白细胞介素29的生产方法及重组il-29工程菌
SI1828239T1 (sl) * 2004-12-10 2011-11-30 Zymogenetics Inc Proizvodnja fgf18 v prokariotskih gostiteljih
JP4987001B2 (ja) * 2005-07-20 2012-07-25 ザイモジェネティクス リミテッド ライアビリティ カンパニー 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法
DK1931704T3 (da) 2005-10-04 2011-03-14 Zymogenetics L L C Frembringelse og rensning af IL-29

Also Published As

Publication number Publication date
US20100003722A1 (en) 2010-01-07
JP2013099337A (ja) 2013-05-23
WO2007041713A1 (en) 2007-04-12
CY1112323T1 (el) 2015-12-09
IL189994A (en) 2013-08-29
CA2625208A1 (en) 2007-04-12
US20080096252A1 (en) 2008-04-24
US7759092B2 (en) 2010-07-20
JP2009510173A (ja) 2009-03-12
SI1931704T1 (sl) 2011-04-29
IL189994A0 (en) 2008-08-07
PL1931704T3 (pl) 2011-06-30
JP5364375B2 (ja) 2013-12-11
IL227691A0 (en) 2013-09-30
US20100222552A1 (en) 2010-09-02
DE602006018969D1 (de) 2011-01-27
US20130143270A1 (en) 2013-06-06
US20120271037A1 (en) 2012-10-25
AU2006299339B2 (en) 2012-03-15
US20120015403A1 (en) 2012-01-19
US8759027B2 (en) 2014-06-24
EP1931704A1 (de) 2008-06-18
AU2006299339A1 (en) 2007-04-12
DK1931704T3 (da) 2011-03-14
US8211670B2 (en) 2012-07-03
EP1931704B1 (de) 2010-12-15
ES2357152T3 (es) 2011-04-19
US7968315B2 (en) 2011-06-28
JP2012235789A (ja) 2012-12-06
PT1931704E (pt) 2011-03-28

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