ATE491722T1 - Herstellung und reinigung von il-29 - Google Patents
Herstellung und reinigung von il-29Info
- Publication number
- ATE491722T1 ATE491722T1 AT06816409T AT06816409T ATE491722T1 AT E491722 T1 ATE491722 T1 AT E491722T1 AT 06816409 T AT06816409 T AT 06816409T AT 06816409 T AT06816409 T AT 06816409T AT E491722 T1 ATE491722 T1 AT E491722T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- production
- purification
- coli
- vectors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72354405P | 2005-10-04 | 2005-10-04 | |
PCT/US2006/039139 WO2007041713A1 (en) | 2005-10-04 | 2006-10-04 | Production and purification of il-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE491722T1 true ATE491722T1 (de) | 2011-01-15 |
Family
ID=37603659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06816409T ATE491722T1 (de) | 2005-10-04 | 2006-10-04 | Herstellung und reinigung von il-29 |
Country Status (15)
Country | Link |
---|---|
US (6) | US20080096252A1 (de) |
EP (1) | EP1931704B1 (de) |
JP (3) | JP5364375B2 (de) |
AT (1) | ATE491722T1 (de) |
AU (1) | AU2006299339B2 (de) |
CA (1) | CA2625208A1 (de) |
CY (1) | CY1112323T1 (de) |
DE (1) | DE602006018969D1 (de) |
DK (1) | DK1931704T3 (de) |
ES (1) | ES2357152T3 (de) |
IL (2) | IL189994A (de) |
PL (1) | PL1931704T3 (de) |
PT (1) | PT1931704E (de) |
SI (1) | SI1931704T1 (de) |
WO (1) | WO2007041713A1 (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001296962A1 (en) | 2000-09-29 | 2002-04-08 | Schering Corporation | Pegylated interleukin-10 |
US7038032B2 (en) | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
WO2005023862A2 (en) * | 2003-08-07 | 2005-03-17 | Zymogenetics, Inc. | Homogeneous preparations of il-28 and il-29 |
JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
AU2006269908A1 (en) * | 2005-07-20 | 2007-01-25 | Bristol-Myers Squibb Company | IL28 and IL29 truncated cysteine mutants and antiviral methods of using same |
DK1931704T3 (da) | 2005-10-04 | 2011-03-14 | Zymogenetics L L C | Frembringelse og rensning af IL-29 |
CL2008002053A1 (es) | 2007-07-17 | 2009-05-22 | Hoffmann La Roche | Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion. |
AR067536A1 (es) * | 2007-07-17 | 2009-10-14 | Hoffmann La Roche | Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea |
WO2009036510A1 (en) * | 2007-09-20 | 2009-03-26 | Commonwealth Scientific And Industrial Research Organisation | Novel avian cytokines and genetic sequences encoding same |
US20110034672A1 (en) * | 2008-01-18 | 2011-02-10 | Roberto Falkenstein | Purification of not-glycosylated polypeptides |
WO2009149377A1 (en) | 2008-06-05 | 2009-12-10 | Zymogenetics, Llc | Use of pegylated type iii interferons for the treatment of hepatitis c |
DK2350271T3 (en) | 2008-11-20 | 2016-04-04 | Biogen Ma Inc | ARGININ INACTIVATION OF ENVIRONMENT VIRA |
US8691205B2 (en) | 2008-12-17 | 2014-04-08 | Merck Sharp & Dohme Corporation | Mono- and di-PEG IL-10 production; and uses |
CN102459569B (zh) * | 2009-04-10 | 2018-02-23 | Reg生命科学有限责任公司 | 脂肪酸衍生物的产生 |
EP2535057A2 (de) | 2010-02-09 | 2012-12-19 | Proyecto de Biomedicina Cima, S.L. | Zusammensetzung zur behandlung von infektions- und tumorerkrankungen |
JP5768341B2 (ja) * | 2010-08-04 | 2015-08-26 | 東ソー株式会社 | Fc結合性タンパク質の製造方法 |
CN102584979B (zh) * | 2011-01-18 | 2015-10-14 | 北京凯因科技股份有限公司 | PEG化干扰素λ |
US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
WO2013028233A1 (en) * | 2011-08-25 | 2013-02-28 | Nanogen Pharmaceutical Biotechnology | Peg-interferon lambda 1 conjugates |
US8454947B1 (en) | 2012-03-01 | 2013-06-04 | Nanogen Pharmaceutical Biotechnology | PEG-interferon lambda 1 conjugates |
RU2549710C2 (ru) * | 2012-06-29 | 2015-04-27 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа |
JP6086378B2 (ja) * | 2012-11-30 | 2017-03-01 | 国立大学法人お茶の水女子大学 | 組み換えヒト膵臓リパーゼの調製方法 |
CN104045704B (zh) * | 2013-03-11 | 2016-08-10 | 中国医学科学院基础医学研究所 | PEG化重组人IFN-λ1、其制备方法和用途 |
CN105209054A (zh) | 2013-04-18 | 2015-12-30 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素-10治疗疾病和病症的方法 |
AU2014281828B2 (en) | 2013-06-17 | 2019-05-09 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
US20160159853A1 (en) * | 2013-07-19 | 2016-06-09 | Biogenomics Limited | Apparatus for refolding of recombinant proteins |
JP6509867B2 (ja) | 2013-08-30 | 2019-05-08 | アルモ・バイオサイエンシーズ・インコーポレイテッド | 疾患及び障害を治療するためにインターロイキン−10を使用する方法 |
JP6660297B2 (ja) | 2013-11-11 | 2020-03-11 | アルモ・バイオサイエンシーズ・インコーポレイテッド | 疾患及び障害を処置するためのインターロイキン−10の使用方法 |
JP6730926B2 (ja) * | 2014-01-08 | 2020-07-29 | プロージット ソウル バイオテクノロジー (ベイジン) カンパニー リミテッド | 融合ポリペプチドおよび使用方法 |
US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
WO2015187295A2 (en) | 2014-06-02 | 2015-12-10 | Armo Biosciences, Inc. | Methods of lowering serum cholesterol |
JP2017536098A (ja) | 2014-10-14 | 2017-12-07 | アルモ・バイオサイエンシーズ・インコーポレイテッド | インターロイキン−15組成物及びその使用 |
ES2941234T3 (es) | 2014-10-22 | 2023-05-19 | Armo Biosciences Inc | Métodos de uso de la interleucina-10 para el tratamiento de enfermedades y trastornos |
EP3237441A4 (de) * | 2014-12-23 | 2018-06-06 | Armo Biosciences, Inc. | Verfahren zur verbesserung des ertrags in der produktion rekombinanter proteine |
WO2016126615A1 (en) | 2015-02-03 | 2016-08-11 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
WO2016172342A1 (en) | 2015-04-21 | 2016-10-27 | Eiger Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising lonafarnib and ritonavir |
CN107847583A (zh) | 2015-05-28 | 2018-03-27 | 阿尔莫生物科技股份有限公司 | 用于治疗癌症的聚乙二醇化白细胞介素‑10 |
KR20180038553A (ko) | 2015-08-25 | 2018-04-16 | 아르모 바이오사이언시스 인코포레이티드 | 질환 및 장애를 치료하기 위한 인터류킨-10을 사용하는 방법 |
US10953072B2 (en) | 2016-02-19 | 2021-03-23 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection with interferon lambda |
JP7073363B2 (ja) * | 2016-11-07 | 2022-05-23 | シージェン インコーポレイテッド | 工学的に操作されたシステインキャップの分配 |
EP3927733A4 (de) | 2019-02-24 | 2022-07-06 | Oncosimis Biotech Private Limited | Verfahren zur kontinuierlichen herstellung von rekombinantem glp-1-peptid durch bakterien |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4795077A (en) * | 1988-05-23 | 1989-01-03 | Motorola Inc. | Bonding method and apparatus |
EP0626448A3 (de) * | 1993-05-26 | 1998-01-14 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Herstellung und Reinigung von alpha-Interferon |
JP2002531089A (ja) * | 1998-11-30 | 2002-09-24 | イーライ・リリー・アンド・カンパニー | 赤血球産生性化合物 |
CZ299516B6 (cs) * | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
DK1294888T3 (da) * | 2000-06-30 | 2007-08-20 | Zymogenetics Inc | Interferonlignende protein Zcyto21 |
US7038032B2 (en) * | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
AU2003286624B2 (en) * | 2002-10-23 | 2008-11-13 | Bristol-Myers Squibb Company | Methods for treating viral infection using IL-28 and IL-29 |
MXPA05006117A (es) * | 2002-12-13 | 2005-09-30 | Zymogenetics Inc | Produccion de il-21 en hospederos procarioticos. |
WO2005023862A2 (en) * | 2003-08-07 | 2005-03-17 | Zymogenetics, Inc. | Homogeneous preparations of il-28 and il-29 |
US20050244423A1 (en) * | 2004-04-02 | 2005-11-03 | Klucher Kevin M | Methods for treating viral infection using IL-28 and IL-29 cysteine mutants |
US7351689B2 (en) * | 2004-07-29 | 2008-04-01 | Zymogenetics, Inc. | Use of IL-28 and IL-29 to treat cancer and autoimmune disorders |
CN1305902C (zh) * | 2004-11-25 | 2007-03-21 | 汕头大学医学院 | 一种人白细胞介素29的生产方法及重组il-29工程菌 |
SI1828239T1 (sl) * | 2004-12-10 | 2011-11-30 | Zymogenetics Inc | Proizvodnja fgf18 v prokariotskih gostiteljih |
JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
DK1931704T3 (da) | 2005-10-04 | 2011-03-14 | Zymogenetics L L C | Frembringelse og rensning af IL-29 |
-
2006
- 2006-10-04 DK DK06816409.4T patent/DK1931704T3/da active
- 2006-10-04 DE DE602006018969T patent/DE602006018969D1/de active Active
- 2006-10-04 AT AT06816409T patent/ATE491722T1/de active
- 2006-10-04 EP EP06816409A patent/EP1931704B1/de active Active
- 2006-10-04 AU AU2006299339A patent/AU2006299339B2/en active Active
- 2006-10-04 PL PL06816409T patent/PL1931704T3/pl unknown
- 2006-10-04 SI SI200630952T patent/SI1931704T1/sl unknown
- 2006-10-04 ES ES06816409T patent/ES2357152T3/es active Active
- 2006-10-04 WO PCT/US2006/039139 patent/WO2007041713A1/en active Application Filing
- 2006-10-04 PT PT06816409T patent/PT1931704E/pt unknown
- 2006-10-04 JP JP2008534712A patent/JP5364375B2/ja active Active
- 2006-10-04 CA CA002625208A patent/CA2625208A1/en not_active Abandoned
- 2006-10-04 US US11/538,688 patent/US20080096252A1/en not_active Abandoned
-
2008
- 2008-03-06 IL IL189994A patent/IL189994A/en active IP Right Grant
-
2009
- 2009-08-07 US US12/537,935 patent/US7759092B2/en active Active
-
2010
- 2010-02-05 US US12/701,358 patent/US7968315B2/en active Active
-
2011
- 2011-03-11 CY CY20111100270T patent/CY1112323T1/el unknown
- 2011-05-24 US US13/114,566 patent/US8211670B2/en active Active
-
2012
- 2012-06-05 US US13/488,840 patent/US20120271037A1/en not_active Abandoned
- 2012-08-01 JP JP2012170709A patent/JP2012235789A/ja active Pending
- 2012-12-19 US US13/720,363 patent/US8759027B2/en active Active
- 2012-12-27 JP JP2012284581A patent/JP2013099337A/ja active Pending
-
2013
- 2013-07-29 IL IL227691A patent/IL227691A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20100003722A1 (en) | 2010-01-07 |
JP2013099337A (ja) | 2013-05-23 |
WO2007041713A1 (en) | 2007-04-12 |
CY1112323T1 (el) | 2015-12-09 |
IL189994A (en) | 2013-08-29 |
CA2625208A1 (en) | 2007-04-12 |
US20080096252A1 (en) | 2008-04-24 |
US7759092B2 (en) | 2010-07-20 |
JP2009510173A (ja) | 2009-03-12 |
SI1931704T1 (sl) | 2011-04-29 |
IL189994A0 (en) | 2008-08-07 |
PL1931704T3 (pl) | 2011-06-30 |
JP5364375B2 (ja) | 2013-12-11 |
IL227691A0 (en) | 2013-09-30 |
US20100222552A1 (en) | 2010-09-02 |
DE602006018969D1 (de) | 2011-01-27 |
US20130143270A1 (en) | 2013-06-06 |
US20120271037A1 (en) | 2012-10-25 |
AU2006299339B2 (en) | 2012-03-15 |
US20120015403A1 (en) | 2012-01-19 |
US8759027B2 (en) | 2014-06-24 |
EP1931704A1 (de) | 2008-06-18 |
AU2006299339A1 (en) | 2007-04-12 |
DK1931704T3 (da) | 2011-03-14 |
US8211670B2 (en) | 2012-07-03 |
EP1931704B1 (de) | 2010-12-15 |
ES2357152T3 (es) | 2011-04-19 |
US7968315B2 (en) | 2011-06-28 |
JP2012235789A (ja) | 2012-12-06 |
PT1931704E (pt) | 2011-03-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE491722T1 (de) | Herstellung und reinigung von il-29 | |
ATE492633T1 (de) | Polypeptide mit cellobiohydrolaseaktivität und dafür kodierende polynukleotide | |
CY1110860T1 (el) | Αναστροφη μεταγραφαση τελομερασης πτηνου | |
ATE515568T1 (de) | Polypeptide mit endoglucanase-aktivtät und dafür codierende polynukleotide | |
ATE470702T1 (de) | Verfahren zur herstellung von permanenten humanen zelllinien | |
BRPI0613770A2 (pt) | anticorpos anti-cd26 e métodos de uso destes | |
WO2011150133A3 (en) | Fibronectin based scaffold proteins having improved stability | |
EA201270713A1 (ru) | Белки на основе фибронектина с каркасными доменами, которые связывают ил-23 | |
MX2009012846A (es) | Polipeptidos que tienen actividad celulosica mejorada y polinucleotidos que los codifican. | |
WO2010099477A3 (en) | Polypeptide structural motifs associated with cell signaling activity | |
BR112012008054A2 (pt) | domínios catalíticos de lisil oxidase e loxl2 | |
ATE513907T1 (de) | Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung | |
TW200740841A (en) | Polypeptides having antimicrobial activity and polynucleotides encoding same | |
FI3581650T3 (fi) | IX-tekijän polypeptidimutantti, sen käyttöjä ja menetelmä sen valmistamiseksi | |
BR112013003522A8 (pt) | "polipeptídeos relaxina modificados compreendendo um aminoácido não codificado naturalmente, uso, método de preparação, bem como ácido nucleico codificando os mesmos" | |
MX339031B (es) | Peptidos intestinales vasoactivos modificados. | |
DE602006010051D1 (de) | Polypeptide mit endoglucanase-aktivtät und dafür codierende polynukleotide | |
EA200701592A1 (ru) | Композиты и способы их получения и использования | |
EA201300056A1 (ru) | Полипептид с активностью ацетилксиланэстеразы и его применения | |
EA201300057A1 (ru) | Полипептид, обладающий углеводдеградирующей активностью, и его применения | |
TW200734350A (en) | Polypeptides having antimicrobial activity and polynucleotides encoding same | |
BRPI0515904A (pt) | processo para purificar uma mistura gasosa compreendendo monóxido de dinitrogênio, uso de uma mistura gasosa, e, processo para preparar uma cetona | |
EA201300059A1 (ru) | Полипептид, обладающий активностью сволленина, и его применение | |
TW200700076A (en) | Polypeptides having antimicrobial activity and polynucleotides encoding same | |
AR051489A1 (es) | Polipeptidos que tienen actividad antimicrobiana y polinucleotidos que los codifican |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1931704 Country of ref document: EP |