ATE281455T1 - Oxindolderivate - Google Patents
OxindolderivateInfo
- Publication number
- ATE281455T1 ATE281455T1 AT01950642T AT01950642T ATE281455T1 AT E281455 T1 ATE281455 T1 AT E281455T1 AT 01950642 T AT01950642 T AT 01950642T AT 01950642 T AT01950642 T AT 01950642T AT E281455 T1 ATE281455 T1 AT E281455T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- oxindol derivatives
- oxindol
- oxindole derivatives
- methods
- Prior art date
Links
- JYGFTBXVXVMTGB-UHFFFAOYSA-N indolin-2-one Chemical class C1=CC=C2NC(=O)CC2=C1 JYGFTBXVXVMTGB-UHFFFAOYSA-N 0.000 title 1
- 125000004095 oxindolyl group Chemical class N1(C(CC2=CC=CC=C12)=O)* 0.000 abstract 2
- 102000013701 Cyclin-Dependent Kinase 4 Human genes 0.000 abstract 1
- 108010025464 Cyclin-Dependent Kinase 4 Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- WCUZQRJNLHUKTA-UHFFFAOYSA-N pyrrolo[3,2-f]quinolin-2-one Chemical class C1=CN=C2C=CC3=NC(=O)C=C3C2=C1 WCUZQRJNLHUKTA-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23024100P | 2000-09-01 | 2000-09-01 | |
| PCT/US2001/020703 WO2002020524A1 (en) | 2000-09-01 | 2001-06-28 | Oxindole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE281455T1 true ATE281455T1 (de) | 2004-11-15 |
Family
ID=22864461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01950642T ATE281455T1 (de) | 2000-09-01 | 2001-06-28 | Oxindolderivate |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6720332B2 (de) |
| EP (1) | EP1313732B1 (de) |
| JP (1) | JP2004508372A (de) |
| AT (1) | ATE281455T1 (de) |
| AU (1) | AU2001271611A1 (de) |
| DE (1) | DE60106947T2 (de) |
| ES (1) | ES2230337T3 (de) |
| WO (1) | WO2002020524A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000071102A2 (en) * | 1999-05-19 | 2000-11-30 | Neurosearch A/S | Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders |
| WO2003062236A1 (en) | 2002-01-22 | 2003-07-31 | Warner-Lambert Company Llc | 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d]PYRIMIDIN-7-ONES |
| DE602004017474D1 (de) * | 2003-07-11 | 2008-12-11 | Warner Lambert Co | Isethionat salz eines selektiven cdk4 inhibitors |
| JP2007513967A (ja) * | 2003-12-11 | 2007-05-31 | セラヴァンス， インコーポレーテッド | 変異レセプターチロシンキナーゼが駆動する細胞増殖性疾患の処置において使用するための組成物 |
| US7304074B2 (en) | 2005-04-05 | 2007-12-04 | Hoffmann-La Roche Inc. | Substituted 1,5-naphthyridine azolinones |
| ES2685171T3 (es) | 2010-06-14 | 2018-10-05 | The Scripps Research Institute | Reprogramación de células a un nuevo destino |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9716557D0 (en) | 1997-08-06 | 1997-10-08 | Glaxo Group Ltd | Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity |
| GB9718913D0 (en) * | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Substituted oxindole derivatives |
| GB9904933D0 (en) * | 1999-03-04 | 1999-04-28 | Glaxo Group Ltd | Compounds |
-
2001
- 2001-06-28 ES ES01950642T patent/ES2230337T3/es not_active Expired - Lifetime
- 2001-06-28 US US10/362,744 patent/US6720332B2/en not_active Expired - Fee Related
- 2001-06-28 DE DE60106947T patent/DE60106947T2/de not_active Expired - Fee Related
- 2001-06-28 WO PCT/US2001/020703 patent/WO2002020524A1/en active IP Right Grant
- 2001-06-28 AT AT01950642T patent/ATE281455T1/de not_active IP Right Cessation
- 2001-06-28 JP JP2002525145A patent/JP2004508372A/ja active Pending
- 2001-06-28 EP EP01950642A patent/EP1313732B1/de not_active Expired - Lifetime
- 2001-06-28 AU AU2001271611A patent/AU2001271611A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2230337T3 (es) | 2005-05-01 |
| DE60106947D1 (de) | 2004-12-09 |
| WO2002020524A1 (en) | 2002-03-14 |
| AU2001271611A1 (en) | 2002-03-22 |
| EP1313732B1 (de) | 2004-11-03 |
| DE60106947T2 (de) | 2005-11-10 |
| US20030195189A1 (en) | 2003-10-16 |
| US6720332B2 (en) | 2004-04-13 |
| EP1313732A1 (de) | 2003-05-28 |
| JP2004508372A (ja) | 2004-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |