ATE262892T1 - Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms - Google Patents

Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms

Info

Publication number
ATE262892T1
ATE262892T1 AT98925862T AT98925862T ATE262892T1 AT E262892 T1 ATE262892 T1 AT E262892T1 AT 98925862 T AT98925862 T AT 98925862T AT 98925862 T AT98925862 T AT 98925862T AT E262892 T1 ATE262892 T1 AT E262892T1
Authority
AT
Austria
Prior art keywords
irgitable
resiniferatoxin
treatment
composition containing
bowel syndrome
Prior art date
Application number
AT98925862T
Other languages
English (en)
Inventor
Fiona Kate Gardiner
Original Assignee
Reckitt Benckiser Healthcare
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt Benckiser Healthcare filed Critical Reckitt Benckiser Healthcare
Application granted granted Critical
Publication of ATE262892T1 publication Critical patent/ATE262892T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98925862T 1997-06-10 1998-06-08 Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms ATE262892T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711962.2A GB9711962D0 (en) 1997-06-10 1997-06-10 Therapeutically active compositions
PCT/GB1998/001673 WO1998056356A1 (en) 1997-06-10 1998-06-08 Therapeutically active compositions

Publications (1)

Publication Number Publication Date
ATE262892T1 true ATE262892T1 (de) 2004-04-15

Family

ID=10813845

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98925862T ATE262892T1 (de) 1997-06-10 1998-06-08 Verwendung einer zusammensetzung enthaltend capsaicin oder resiniferatoxin zur behandlung des reizdarmsyndroms

Country Status (17)

Country Link
US (1) US6201014B1 (de)
EP (1) EP0988028B1 (de)
JP (1) JP2002513418A (de)
KR (1) KR20010013618A (de)
CN (1) CN1198594C (de)
AR (1) AR012960A1 (de)
AT (1) ATE262892T1 (de)
AU (1) AU737606B2 (de)
BR (1) BR9809994A (de)
CA (1) CA2291796C (de)
DE (1) DE69822822T2 (de)
GB (3) GB9711962D0 (de)
HU (1) HUP0004245A2 (de)
ID (1) ID22878A (de)
PL (1) PL337337A1 (de)
WO (1) WO1998056356A1 (de)
ZA (1) ZA984920B (de)

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US20110071468A1 (en) * 1998-06-04 2011-03-24 Mederi Therapeutics, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US6802841B2 (en) * 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
GB9812426D0 (en) * 1998-06-10 1998-08-05 Reckitt & Colmann Prod Ltd Improvements in or relating to organic compositions
GB9925127D0 (en) * 1999-10-22 1999-12-22 Pharmacia & Upjohn Spa Oral formulations for anti-tumor compounds
JP5042425B2 (ja) * 2000-03-01 2012-10-03 ユーロセルティック ソシエテ アノニム 機能性胃腸疾患治療用トラマドール
US7192612B2 (en) * 2001-02-22 2007-03-20 Purdue Research Foundation Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
AU2002254007B2 (en) 2001-02-22 2006-09-21 Purdue Research Foundation Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
US6428822B1 (en) 2001-04-03 2002-08-06 Chengzhi Life Science Company, Ltd. Extracts of mixed arctium lappa L., carrot and whole radish for treating hypertension, constipation and detoxification
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
WO2003086441A1 (en) * 2002-04-12 2003-10-23 Pangenomics Co., Ltd Crude drug composition for preventing and treating gastrointestinal dyskinetic diseases
AU2003299691B2 (en) * 2002-12-18 2008-06-05 Algorx Pharmaceuticals, Inc. Administration of capsaicinoids
ES2311756T3 (es) * 2002-12-18 2009-02-16 Algorx Administracion de la capsiacina.
BRPI0409748A (pt) * 2003-04-08 2006-10-24 Algorx Pharmaceuticals Inc preparação e purificação de capsaicin sintetico
US20100159000A1 (en) * 2003-11-10 2010-06-24 Lundeen Sr James E Medicine for treating gastrointestinal disorder including fecal incontinence
AT413646B (de) * 2004-04-02 2006-04-15 Hammer Johann Dr Verwendung von capsaicin und/oder capsaicinoiden
US20050277657A1 (en) * 2004-06-15 2005-12-15 Dusan Ninkov Method of protection of biologically active essential oils and pharmaceutical composition for weight control and enhance fat burning in adults, adolescents and children
CN101119713A (zh) * 2004-11-24 2008-02-06 阿尔高克斯制药公司 类辣椒素凝胶制剂及其用途
WO2006069451A1 (de) 2004-12-28 2006-07-06 Mestex Ag Verwendung von resiniferatoxin (rtx) für die herstellung eines mittels zur behandlung von gelenkschmerzen und verfahren zur applikation dieses mittels
EP2096927B1 (de) 2006-10-27 2012-10-10 BMB Patent Holding Corporation Therapeutische zusammensetzungen und behandlungsverfahren mit capsianosidartigen verbindungen
EP2187979B1 (de) * 2007-08-29 2014-09-24 Sorbent Therapeutics, Inc. Saugfähige polymer-zusammensetzungen mit variierendem gegenionen-gehalt und ihre herstellungs- und anwendungsverfahren
KR20090047637A (ko) * 2007-11-08 2009-05-13 재단법인서울대학교산학협력재단 커큐민 또는 이의 약학적으로 허용가능한 염을유효성분으로 함유하는 통증 예방 및 치료용 조성물
HUP0700755A2 (en) * 2007-11-26 2009-08-28 Pannonpharma Gyogyszergyar Pharmaceutical compositions containing capsaicionoid and non-steroidal anti-inflammatory drug
US8697155B2 (en) * 2008-07-22 2014-04-15 Mayo Foundation For Medical Education And Research Treatment of obesity and related disorders
US20110200669A1 (en) * 2010-02-15 2011-08-18 Winston Laboratories, Inc. Method and compositions of civamide to treat disease of the intestines
KR101378973B1 (ko) * 2012-04-13 2014-03-28 한미약품 주식회사 구형에 가까운 형태의 다중 투여 단위 정제를 포함하는 경질 캡슐 복합 제형 및 이의 제조방법
CN103027901B (zh) * 2012-12-11 2014-11-12 广东药学院 一种载辣椒素壳聚糖微球肠溶片及其制备方法
US10092528B2 (en) 2013-03-13 2018-10-09 Altria Client Services Llc Application of encapsulated capsaicin and analogues thereof for controlling calorie intake
WO2014152754A2 (en) 2013-03-15 2014-09-25 Cedars-Sinai Medical Center Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens
US9289418B2 (en) 2013-03-15 2016-03-22 Cedars-Sinai Medical Center Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens
MX369540B (es) 2014-01-30 2019-11-11 Omniactive Health Tech Limited Composicion de sustancias oleosas, picantes y odoriferas y un proceso para la preparacion de las mismas.
EP3179983A4 (de) 2014-08-13 2018-01-10 Cedars-Sinai Medical Center Anti-methanogene zusammensetzungen und verwendungen davon
WO2016161085A1 (en) * 2015-04-01 2016-10-06 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
WO2021011002A1 (en) * 2019-07-18 2021-01-21 Dignify Therapeutics, Llc Compositions and methods for inducing defecation
EP4135652A1 (de) * 2020-04-15 2023-02-22 Grünenthal GmbH Zusammensetzungen von resiniferatoxin
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Also Published As

Publication number Publication date
GB9827192D0 (en) 1999-02-03
PL337337A1 (en) 2000-08-14
CA2291796C (en) 2008-03-25
GB2332147B (en) 1999-10-27
CA2291796A1 (en) 1998-12-17
CN1198594C (zh) 2005-04-27
GB9811819D0 (en) 1998-07-29
AR012960A1 (es) 2000-11-22
DE69822822D1 (de) 2004-05-06
AU737606B2 (en) 2001-08-23
ID22878A (id) 1999-12-16
US6201014B1 (en) 2001-03-13
JP2002513418A (ja) 2002-05-08
GB2332147A (en) 1999-06-16
CN1259863A (zh) 2000-07-12
AU7782998A (en) 1998-12-30
HUP0004245A2 (hu) 2001-08-28
ZA984920B (en) 1999-07-01
WO1998056356A1 (en) 1998-12-17
GB9711962D0 (en) 1997-08-06
KR20010013618A (ko) 2001-02-26
EP0988028A1 (de) 2000-03-29
DE69822822T2 (de) 2005-01-13
EP0988028B1 (de) 2004-03-31
BR9809994A (pt) 2000-08-01

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