ATE239739T1 - Phospholipid-derivate von nichtsteroiden entzündungshemmenden medikamenten - Google Patents
Phospholipid-derivate von nichtsteroiden entzündungshemmenden medikamentenInfo
- Publication number
- ATE239739T1 ATE239739T1 AT99956297T AT99956297T ATE239739T1 AT E239739 T1 ATE239739 T1 AT E239739T1 AT 99956297 T AT99956297 T AT 99956297T AT 99956297 T AT99956297 T AT 99956297T AT E239739 T1 ATE239739 T1 AT E239739T1
- Authority
- AT
- Austria
- Prior art keywords
- inflammatory drugs
- phospholipide
- derivatives
- steroid anti
- compounds
- Prior art date
Links
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003904 phospholipids Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/106—Adducts, complexes, salts of phosphatides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL12714398A IL127143A0 (en) | 1998-11-19 | 1998-11-19 | Phospholipid terivatives of non-steroidal anti inflammatory drugs |
| PCT/IL1999/000623 WO2000031083A1 (en) | 1998-11-19 | 1999-11-18 | Phospholipid derivatives of non-steroidal anti-inflammatory drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239739T1 true ATE239739T1 (de) | 2003-05-15 |
Family
ID=11072158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99956297T ATE239739T1 (de) | 1998-11-19 | 1999-11-18 | Phospholipid-derivate von nichtsteroiden entzündungshemmenden medikamenten |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6730696B1 (de) |
| EP (1) | EP1131326B1 (de) |
| JP (1) | JP2002530410A (de) |
| AT (1) | ATE239739T1 (de) |
| AU (1) | AU766045B2 (de) |
| CA (1) | CA2346869C (de) |
| DE (1) | DE69907720T2 (de) |
| IL (1) | IL127143A0 (de) |
| NZ (1) | NZ510938A (de) |
| WO (1) | WO2000031083A1 (de) |
| ZA (1) | ZA200102718B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL127143A0 (en) * | 1998-11-19 | 1999-09-22 | Dpharm Ltd | Phospholipid terivatives of non-steroidal anti inflammatory drugs |
| WO2003068242A1 (en) * | 2002-02-11 | 2003-08-21 | Vertex Pharmaceuticals Incorporated | Phospholipids as caspase inhibitor prodrugs |
| US20070053984A1 (en) * | 2005-03-03 | 2007-03-08 | Monique Spann-Wade | Topical gels compositions |
| DE102006019907A1 (de) * | 2006-04-28 | 2007-10-31 | Müller-Enoch, Dieter, Prof. Dr. | Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung |
| US20080317684A1 (en) * | 2006-09-06 | 2008-12-25 | Isw Group, Inc. | Topical Compositions |
| US20100278836A1 (en) * | 2007-10-30 | 2010-11-04 | Athera Biotechnologies Ab | Diagnostic and therapeutic methods and compositions for cardiovascular disease |
| EP2646056A1 (de) * | 2010-12-02 | 2013-10-09 | Ben Gurion University of the Negev Research and Development Authority | Konjugate eines phospholipids und arzneimittel zur behandlung von entzündlichen darmerkrankungen |
| WO2021262892A1 (en) * | 2020-06-23 | 2021-12-30 | The Trustees Of The University Of Pennsylvania | Compositions and methods of using a pla2-responsive drug delivery system |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223263A (en) | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
| US5352673A (en) * | 1989-08-29 | 1994-10-04 | Dennis Edward A | Prodrugs |
| WO1991016920A1 (en) | 1990-05-07 | 1991-11-14 | Vical, Inc. | Lipid prodrugs of salicylate and nonsteroidal anti-inflammatory drugs |
| US5563257A (en) * | 1990-08-20 | 1996-10-08 | Boehringer Mannheim Gmbh | Phospholipid derivatives of nucleosides |
| US5256641A (en) | 1990-11-01 | 1993-10-26 | State Of Oregon | Covalent polar lipid-peptide conjugates for immunological targeting |
| US5149794A (en) | 1990-11-01 | 1992-09-22 | State Of Oregon | Covalent lipid-drug conjugates for drug targeting |
| US5543389A (en) | 1990-11-01 | 1996-08-06 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non Profit Organization | Covalent polar lipid-peptide conjugates for use in salves |
| EP0594677A4 (en) | 1991-07-12 | 1997-09-17 | Vical Inc | Antiviral liponucleosides: treatment of hepatitis b |
| JPH07188280A (ja) * | 1993-12-28 | 1995-07-25 | L T T Kenkyusho:Kk | ホスファチジルエタノールアミン類結合生理活性物質およびその中間体 |
| US5534499A (en) * | 1994-05-19 | 1996-07-09 | The University Of British Columbia | Lipophilic drug derivatives for use in liposomes |
| ATE218872T1 (de) | 1995-01-27 | 2002-06-15 | Univ Texas | Verfahren zur erhöhung der therapeutischen wirkung von nsaids und dazu verwendbare zwitterionische phospholipidhaltige zusammensetungen |
| JP3781877B2 (ja) * | 1997-10-03 | 2006-05-31 | 株式会社ムック | アスコルビン酸誘導体またはその塩、および医薬 |
| IL127143A0 (en) * | 1998-11-19 | 1999-09-22 | Dpharm Ltd | Phospholipid terivatives of non-steroidal anti inflammatory drugs |
-
1998
- 1998-11-19 IL IL12714398A patent/IL127143A0/xx unknown
-
1999
- 1999-11-18 EP EP99956297A patent/EP1131326B1/de not_active Expired - Lifetime
- 1999-11-18 US US09/856,009 patent/US6730696B1/en not_active Expired - Fee Related
- 1999-11-18 WO PCT/IL1999/000623 patent/WO2000031083A1/en active IP Right Grant
- 1999-11-18 CA CA2346869A patent/CA2346869C/en not_active Expired - Fee Related
- 1999-11-18 AU AU12928/00A patent/AU766045B2/en not_active Ceased
- 1999-11-18 NZ NZ510938A patent/NZ510938A/xx not_active IP Right Cessation
- 1999-11-18 JP JP2000583911A patent/JP2002530410A/ja active Pending
- 1999-11-18 AT AT99956297T patent/ATE239739T1/de not_active IP Right Cessation
- 1999-11-18 DE DE69907720T patent/DE69907720T2/de not_active Expired - Lifetime
-
2001
- 2001-04-03 ZA ZA200102718A patent/ZA200102718B/en unknown
-
2004
- 2004-01-14 US US10/757,098 patent/US7173018B2/en not_active Expired - Lifetime
-
2006
- 2006-12-20 US US11/643,189 patent/US7417035B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NZ510938A (en) | 2002-11-26 |
| EP1131326A1 (de) | 2001-09-12 |
| IL127143A0 (en) | 1999-09-22 |
| CA2346869A1 (en) | 2000-06-02 |
| US7173018B2 (en) | 2007-02-06 |
| WO2000031083A1 (en) | 2000-06-02 |
| AU766045B2 (en) | 2003-10-09 |
| US20070191310A1 (en) | 2007-08-16 |
| JP2002530410A (ja) | 2002-09-17 |
| EP1131326A4 (de) | 2002-03-27 |
| ZA200102718B (en) | 2001-10-05 |
| US7417035B2 (en) | 2008-08-26 |
| DE69907720T2 (de) | 2004-02-26 |
| CA2346869C (en) | 2010-03-23 |
| US20040147485A1 (en) | 2004-07-29 |
| EP1131326B1 (de) | 2003-05-07 |
| AU1292800A (en) | 2000-06-13 |
| DE69907720D1 (de) | 2003-06-12 |
| US6730696B1 (en) | 2004-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |