ATE199260T1 - Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzieren - Google Patents

Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzieren

Info

Publication number
ATE199260T1
ATE199260T1 AT94927602T AT94927602T ATE199260T1 AT E199260 T1 ATE199260 T1 AT E199260T1 AT 94927602 T AT94927602 T AT 94927602T AT 94927602 T AT94927602 T AT 94927602T AT E199260 T1 ATE199260 T1 AT E199260T1
Authority
AT
Austria
Prior art keywords
peptides
hiv
nucleotide sequences
sequences
fusion
Prior art date
Application number
AT94927602T
Other languages
English (en)
Inventor
Hermann Katinger
Thomas Muster
Original Assignee
Polymun Scient Immunbio Forsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polymun Scient Immunbio Forsch filed Critical Polymun Scient Immunbio Forsch
Application granted granted Critical
Publication of ATE199260T1 publication Critical patent/ATE199260T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT94927602T 1993-09-11 1994-09-12 Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzieren ATE199260T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93114631 1993-09-11
PCT/EP1994/003039 WO1995007354A1 (en) 1993-09-11 1994-09-12 Peptides that elicit neutralizing antibodies against genetically divergent hiv-1 strains

Publications (1)

Publication Number Publication Date
ATE199260T1 true ATE199260T1 (de) 2001-03-15

Family

ID=8213253

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94927602T ATE199260T1 (de) 1993-09-11 1994-09-12 Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzieren

Country Status (15)

Country Link
EP (1) EP0725825B1 (de)
JP (1) JPH09502348A (de)
CN (1) CN1135237A (de)
AT (1) ATE199260T1 (de)
AU (1) AU682893B2 (de)
BR (1) BR9407531A (de)
CA (1) CA2171544C (de)
CZ (1) CZ287808B6 (de)
DE (1) DE69426725T2 (de)
ES (1) ES2156902T3 (de)
HU (1) HU219507B (de)
PT (1) PT725825E (de)
RU (1) RU2181379C2 (de)
UA (1) UA43350C2 (de)
WO (1) WO1995007354A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69527089T2 (de) * 1995-04-19 2003-01-02 Polymun Scientific Immunbiologische Forschung Gmbh, Wien Monoklonale antikörper gegen hiv-1 und davon hergestellte impfstoffe
US6319890B1 (en) 1996-12-30 2001-11-20 Manfred P. Dierich Inhibition of binding of complement Factor H
NZ507083A (en) * 1998-03-23 2003-10-31 Trimeris Inc Methods and compositions for peptide synthesis, in particular T-20 (DP-178) and T-20-like peptides
US6482928B1 (en) 1999-04-13 2002-11-19 Aventis Pasteur Limited And University Of Toronto Fab′-epitope complex from HIV-1 cross-neutralizing monoclonal antibody 2F5
CN1172717C (zh) * 2000-08-18 2004-10-27 清华大学 一种治疗艾滋病的药物及其制备方法
FR2851165A1 (fr) * 2003-02-19 2004-08-20 Aventis Pasteur Antigene derivant de l'helice c de la proteine gp41
EP1868651A4 (de) 2005-04-12 2010-10-06 Univ Duke Verfahren zur induktion von neutralisierenden antikörpern gegen das hiv-virus
EP1754715A1 (de) 2005-08-19 2007-02-21 Bundesrepublik Deutschland vertreten durch das Bundesminsterium für Gesundheit, dieses vertr. durch das Robert-Koch-Institut Impfstoff auf Basis virusneutralisierender Antikörper
EP2139516A4 (de) 2007-04-13 2011-06-29 Univ Duke Verfahren zur induzierung neutralisierender antikörper gegen hiv
CA2750067C (en) * 2009-02-06 2018-08-21 Mymetics Corporation Splitting gp41
US10076567B2 (en) 2013-09-27 2018-09-18 Duke University MPER-liposome conjugates and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2053413T3 (es) * 1992-05-14 1997-11-16 Polymun Scient Immunbio Forsch Peptidos que inducen anticuerpos que neutralizan aislados de vih-1 geneticamente divergentes.
US5817767A (en) * 1993-02-24 1998-10-06 Progenics Pharmaceuticals, Inc. Synergistic composition of CD4-based protein and anti-HIV-1 antibody, and methods of using same

Also Published As

Publication number Publication date
HUT76102A (en) 1997-06-30
CZ74196A3 (en) 1996-07-17
EP0725825A1 (de) 1996-08-14
UA43350C2 (uk) 2001-12-17
WO1995007354A1 (en) 1995-03-16
HU9600587D0 (en) 1996-05-28
PT725825E (pt) 2001-08-30
EP0725825B1 (de) 2001-02-21
DE69426725T2 (de) 2001-09-06
RU2181379C2 (ru) 2002-04-20
CN1135237A (zh) 1996-11-06
CA2171544C (en) 2003-06-24
AU7696594A (en) 1995-03-27
AU682893B2 (en) 1997-10-23
CZ287808B6 (en) 2001-02-14
JPH09502348A (ja) 1997-03-11
BR9407531A (pt) 1997-08-26
CA2171544A1 (en) 1995-03-16
ES2156902T3 (es) 2001-08-01
HU219507B (hu) 2001-04-28
DE69426725D1 (de) 2001-03-29

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Legal Events

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