AR044200A1 - Composicion de fondaparinux sodico de alta pureza ,un procedimiento de preparacion de esta composicion y composiciones farmaceuticas que la contienen como principio activo - Google Patents

Composicion de fondaparinux sodico de alta pureza ,un procedimiento de preparacion de esta composicion y composiciones farmaceuticas que la contienen como principio activo

Info

Publication number
AR044200A1
AR044200A1 ARP040100513A ARP040100513A AR044200A1 AR 044200 A1 AR044200 A1 AR 044200A1 AR P040100513 A ARP040100513 A AR P040100513A AR P040100513 A ARP040100513 A AR P040100513A AR 044200 A1 AR044200 A1 AR 044200A1
Authority
AR
Argentina
Prior art keywords
composition
pharmaceutical compositions
high purity
fondaparinux
compositions containing
Prior art date
Application number
ARP040100513A
Other languages
English (en)
Inventor
Jean Francois Brannelec
Christian Morello
Pierre Potier
Patrick Trouilleux
Henricus Cornelis Jozephus Claassen
Petrus Marcus Franciscus Maria Bastiaansen
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of AR044200A1 publication Critical patent/AR044200A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Composiciones de fondaparinux sódico de alta pureza (al menos 97 %), procedimientos de preparación de esta composición para su utilización en composiciones farmacéuticas y composiciones farmacéuticas que la contienen como principio activo. Este compuesto es útil para el tratamiento y la prevención de las enfermedades tromboembólicas.
ARP040100513A 2003-02-27 2004-02-19 Composicion de fondaparinux sodico de alta pureza ,un procedimiento de preparacion de esta composicion y composiciones farmaceuticas que la contienen como principio activo AR044200A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37526803A 2003-02-27 2003-02-27

Publications (1)

Publication Number Publication Date
AR044200A1 true AR044200A1 (es) 2005-09-07

Family

ID=32961215

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040100513A AR044200A1 (es) 2003-02-27 2004-02-19 Composicion de fondaparinux sodico de alta pureza ,un procedimiento de preparacion de esta composicion y composiciones farmaceuticas que la contienen como principio activo

Country Status (14)

Country Link
US (1) US20050020536A1 (es)
EP (1) EP1625135B1 (es)
JP (1) JP4594298B2 (es)
AR (1) AR044200A1 (es)
AT (1) ATE427953T1 (es)
CY (1) CY1109168T1 (es)
DE (1) DE602004020459D1 (es)
DK (1) DK1625135T3 (es)
ES (1) ES2322464T3 (es)
HK (1) HK1087719A1 (es)
PT (1) PT1625135E (es)
SI (1) SI1625135T1 (es)
TW (1) TWI335224B (es)
WO (1) WO2004078105A2 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
JP2008541231A (ja) * 2005-05-05 2008-11-20 アーキペラゴ ホールディングス インコーポレイテッド 反内在化注文の変成装置
US7635773B2 (en) 2008-04-28 2009-12-22 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions
WO2010132616A1 (en) * 2009-05-12 2010-11-18 Rsa Protective Technologies, Llc Surface mount vehicle anti-ram security systems
EP3666786A1 (en) 2009-07-31 2020-06-17 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
US20130005954A1 (en) * 2011-06-28 2013-01-03 Apicore, Llc Process for preparing heparinoids and intermediates useful in the synthesis thereof
CN102659859B (zh) * 2012-04-11 2014-12-10 苏州纳微科技有限公司 单分散聚甲基丙烯酸酯离子交换层析介质在磺达肝癸钠柱层析纯化中的应用
CN103570774B (zh) * 2012-08-07 2017-08-25 博瑞生物医药（苏州）股份有限公司 一种戊糖化合物的纯化方法
CA2888822C (en) 2012-10-22 2021-01-26 Cydex Pharmaceuticals, Inc. Alkylated cyclodextrin compositions and processes for preparing and using the same
CN103864862B (zh) * 2012-12-14 2017-10-17 博瑞生物医药（苏州）股份有限公司 一种戊糖化合物的纯化方法
US10072039B2 (en) 2013-07-25 2018-09-11 Scinopharm Taiwan, Ltd. Process for the production of Fondaparinux sodium
WO2015011519A1 (en) 2013-07-25 2015-01-29 Scinopharm Taiwan, Ltd. Process for the production of fondaparinux sodium
US9346844B2 (en) 2013-07-25 2016-05-24 Scinopharm Taiwan, Ltd. Process for the production of fondaparinux sodium
CN103992364B (zh) * 2014-03-25 2016-08-10 南京天翔医药科技有限公司 一种磺达肝癸钠的分离提取方法
CN103965269B (zh) * 2014-04-16 2018-05-04 杭州华东医药集团新药研究院有限公司 低水分高纯度的磺达肝癸钠及其制备方法
US9873712B2 (en) * 2014-10-03 2018-01-23 Amphastar Pharmaceuticals, Inc. Method of purifying idraparinux sodium
US10688249B2 (en) * 2015-06-11 2020-06-23 Virchow Biotech Pvt. Ltd. Multiple dose pharmaceutical compositions containing heparin and/or heparin-like compounds and devices and methods for delivering the same
CN105037452B (zh) * 2015-06-19 2018-10-09 天津红日药业股份有限公司 一种快速制备高纯度磺达肝癸钠的精制方法
CN104910217B (zh) * 2015-06-19 2018-04-17 天津红日药业股份有限公司 用于磺达肝癸钠质量控制的参比化合物
CN107501359B (zh) * 2017-08-24 2020-07-31 深圳市海滨制药有限公司 一种磺达肝癸钠杂质化合物及其制备方法与应用
CN114478663B (zh) * 2020-11-12 2023-12-01 杭州中美华东制药有限公司 一种磺达肝癸钠杂质的制备方法
CN114591379A (zh) * 2021-12-30 2022-06-07 淮北师范大学 一种磺达肝癸钠甲酰化杂质的制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE664087A (es) * 1956-03-29
US4025357A (en) * 1975-04-14 1977-05-24 A. E. Staley Manufacturing Company Ion exchange enrichment of impure dextrose solutions
JPS5577896A (en) * 1978-12-07 1980-06-12 Meiji Seika Kaisha Ltd Preparation of high-purity maltose
FR2456116A1 (fr) * 1979-05-11 1980-12-05 Sarget Lab Nouvelle saponine triterpenique derivee de la caulophyllogenine et ses applications therapeutiques
US4242501A (en) * 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
US4502890A (en) * 1981-03-02 1985-03-05 Calgon Carbon Corporation Purification of sugar liquors with activated carbon
DE3118588C2 (de) * 1981-05-11 1983-07-07 Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung
JPS5899497A (ja) * 1981-11-27 1983-06-13 Snow Brand Milk Prod Co Ltd 新規なオリゴ糖、その製造法及びビフイドバクテリウム菌の増殖促進剤
JPS60102196A (ja) * 1983-11-07 1985-06-06 Daicel Chem Ind Ltd 粗グリコシドの精製処理方法
US4686102A (en) * 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
JPS61118336A (ja) * 1984-11-13 1986-06-05 Yonezawa Kagaku Kogyo Kk ペンタクロルフエノ−ル及びその誘導体の精製法
JPH0673442B2 (ja) * 1986-03-13 1994-09-21 明治製菓株式会社 食品の老化防止方法
SE453394B (sv) * 1986-07-07 1988-02-01 Pharmacia Ab Forfarande for framstellning av sulfaterade polysackarider genom anvendning av ett reducerande medel for sulfateringsreaktionen
JPS6398395A (ja) * 1986-10-16 1988-04-28 Katakura Chitsukarin Kk キトサンオリゴ糖の製造法
US5756721A (en) * 1991-01-16 1998-05-26 National Starch And Chemical Investment Holding Corporation Purification of polysaccharides
US5569756A (en) * 1995-03-21 1996-10-29 American Maize-Products Company Purification of chemically modified cyclodextrins
DE19543052A1 (de) * 1995-11-06 1997-05-07 Schering Ag Verfahren zur Herstellung und Reinigung von Fludarabin-Phosphat und die Verwendung von sauren Ionenaustauschern im Verfahren
AU6897100A (en) * 1999-08-30 2001-03-26 Shell Internationale Research Maatschappij B.V. A process for separation of the dipotassium salt of naphthalene dicarboxylic acid using activated carbon beds

Also Published As

Publication number Publication date
JP4594298B2 (ja) 2010-12-08
JP2006519246A (ja) 2006-08-24
DK1625135T3 (da) 2009-06-22
EP1625135A2 (fr) 2006-02-15
ATE427953T1 (de) 2009-04-15
WO2004078105A2 (fr) 2004-09-16
DE602004020459D1 (de) 2009-05-20
TWI335224B (en) 2011-01-01
ES2322464T3 (es) 2009-06-22
PT1625135E (pt) 2009-07-10
TW200501965A (en) 2005-01-16
SI1625135T1 (sl) 2009-08-31
HK1087719A1 (en) 2006-10-20
EP1625135B1 (fr) 2009-04-08
US20050020536A1 (en) 2005-01-27
WO2004078105A3 (fr) 2004-10-28
CY1109168T1 (el) 2014-07-02

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