cFDAP is a command-line Linux tool for fitting FRAP/FDAP data.

The overall goal of cFDAP is to provide a fast and robust way to extract kinetic parameters from FRAP/FDAP data gathered from outgrowths of living neuronal cells. Nevetheless, the code can be relatively simply adapted to any experiment outline, which, in turn, requires theoretical expressions for FRAP(t)/FDAP(t) signals be hardcoded explicitly (for more details please read Igaev et al. (2015) Biophys. J. 107: 2567-2578).

• 30.08.2016

  A new option "-w" has been introduced which allows the user to choose between weighted and unweighted fitting.

• 09.02.2016

  GSL 2.0 support has been implemented.

• 13.09.2015

  Several bugs have been fixed. From now on, cFDAP and curve/error files must be located in the same folder.

• 12.08.2015

  cFDAP now supports kinetic models with 1 and 2 fit parameters and calculates 95%, 97.5% and 99.9% confidence intervals.

To successfully compile cFDAP, you need to install the GNU Scientific Library (http:https://www.gnu.org/software/gsl/). For Ubuntu/Debian, one needs to install gsl-bin (binary package), libgsl2 (library package) and, optionally, libgsl-dev (development package).

cc cFDAP.c -o cFDAP -lgsl -lgslcblas -lm

To get quick start just run

./cFDAP

cFDAP is licensed under a GPL license. That means that distributing the code is only allowed under the same terms.

• statically linked GSL 2.0
• cFDAP version for Windows 7
• a simple GUI (preferably a Fiji plugin)