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Inversion patching #255

Merged
merged 9 commits into from
Jul 1, 2024
Merged

Inversion patching #255

merged 9 commits into from
Jul 1, 2024

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ekg
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@ekg ekg commented Jun 26, 2024

This adds a way to patch in the reverse complement direction when the forward patching fails. It turns this happen. It actually is capable of detecting inversions in the wflign phase, and these can be as short as detectable with this approach.

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ekg commented Jun 28, 2024

image

image

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ekg commented Jul 1, 2024

This could be improved by recording the successful inverse patches and re-patching around them. It doesn't work exactly this way now.

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ekg commented Jul 1, 2024

In any case, the current setup should avoid the forced forward patches that lead to huge numbers of FP variants.

@ekg ekg merged commit e3dba1b into main Jul 1, 2024
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