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Description:
This analysis tool was develeped for KEGG enrichment analysis according to the published article "Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life".
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Dependencies of R packages
optparse, ggplot2
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For pathway enrichment caculation:
Rscript caculate_reporter_score.R --group group.list --abund KO.rela.xls --type pathway --outdir pathway
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For module enrichment caculation:
Rscript caculate_reporter_score.R --group group.list --abund KO.rela.xls --type module --outdir module
This command will generate two files "stat.ko.res.xls" and "reporter_score.xls". More result interprations, please see the published article.
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Visualization:
Rscript plot_reporter.score.R pathway/reporter_score.xls pathway/
Rscript plot_reporter.score.R module/reporter_score.xls module/
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