Update 41. Effects of Fasting & Time Restricted Eating on Fat Loss & …

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41. Effects of Fasting & Time Restricted Eating on Fat Loss & Health.md

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  <summary>(1:29:15) Non-Alcoholic Fatty Liver </summary>
 The other very exciting finding about intermittent fasting is one of the major health issues these days is the proliferation of so-called non-alcoholic fatty liver disease, 30 years or so non-alcoholic fatty liver disease was exceedingly rare to see in the clinic, except in alcoholics, fatty deposits in the liver are bad. It is essentially liver disease. Nowadays children and adults are showing up with non-alcoholic fatty liver disease. Some of these people are obese, others are not, but it's a serious health concern. And it's growing in numbers all the time. A recent study that was published in Cell Reports Medicine just a couple of weeks ago, tested the hypothesis, whether or not the gut microbiome or so-called brown fat tissue is impacting the liver health. And in particular nonalcoholic fatty liver disease. The short takeaway from this study is that contrary to what was previously thought, the gut microbiome, while very important for a number of other processes in the body doesn't seem to be related to this non-alcoholic fatty liver disease. This is surprising to people or should be to those of you that have been following the gut microbiome literature, however, brown fat, which is a healthy fat that we have between our two scapulae and in our upper neck, it doesn't tend to be blubbery type fat pads, but it sits deep to the skin, but creates a thermogenic effect in the body that is helpful for reducing the amount of other fat, the type of fat that we're more typically used to thinking about and talking about white fat and pink fat that's subcutaneous fat around the abdomen and so forth. Brown fat seems to have a direct correlation with the lack of non-alcoholic fatty liver disease. What this study showed was that in people that have diminished concentrations of brown fat, there is a higher probability of having non-alcoholic fatty liver disease. Now the good news is brown fat stores can be increased. And again, this isn't going to create blubber of brown fat. This is going to create increased thermogenesis and actually make people leaner and brown fat has a number of other important positive effects. Now, this is interesting because cold exposure of anywhere from one to three minutes, two or four times per week, or maybe even 10 minutes, two to four times per week can increase brown fat stores. Also time-restricted feeding has now been tied to the density of brown fat store. So time-restricted feeding also seems to positively increase brown fat stores, probably because of the way that brown fat stores relate to epinephrin and adrenaline, which tend to go up when we're fasted. What does this all mean? This means for sake of liver health and for sake of reducing, or maybe preventing, or even potentially, I want to underline potentially reversing non-alcoholic fatty liver disease, time-restricted feeding also appears to be beneficial. 
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  <summary>(1:32:00) Effects of Fasting on Hormones: Testosterone, Cortisol</summary>