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Provide mutation info with StartLosses #206
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I concur with @joaoe 's suggestion above. It'd be nice to have the aa_alt attribute for this effect class, instead of the p.M1? annotation. |
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Both VEP and ANNOVAR mark start losses but include the information regarding changes in the coding sequence and aminoacids.
For instance, the json from VEP with variant
chr10 58224929 A G
:Would perhaps be nice to annotate these as regular annotations (
Substitution
,Insertion
,Deletion
), and then wrap them with aStartLoss
in a property calledalternate_effect
the same way it happens for ExonicSpliceSite. Or just includeaa_ref
andaa_alt.
(which is not that useful if the annotation has other consequences, like being aFrameshift
orPrematureStop
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