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Term merge: [term labels and ID] symbiont-mediated suppression of RIG-I terms may need a merge #28251

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genegodbold opened this issue Jun 21, 2024 · 2 comments

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@genegodbold
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  • Which term do you propose this term merge into? Provide GO ID and term label
    Hey @pgaudet
  • Terms to be merged: Provide GO ID and term label
    RIG-I terms
    GO:0039540 symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity
    GO:0141078 symbiont-mediated suppression of host RIG-I signaling pathway
    GO:0039545 symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
    GO:0039554 symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity

RIG-I is a member of the RIG-I like receptors (RLRs) that also includes Melanoma Differentiation-Associated protein 5 (MDA5) and Laboratory of genetics physiology 2 (LGP2) RIG-I and MDA5 are both involved in activating MAVS and triggering an antiviral response.

  • Reason for merge
    I think the annotations for GO:0141078 should be merged into GO:0039540

  • Reference(s)
    PMID:nnnnnn

  • Any other information

@pgaudet
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pgaudet commented Jul 2, 2024

Done here #28234

Or are you asking something different?

@pgaudet
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pgaudet commented Jul 2, 2024

@genegodbold confirmed that this is a duplicate.

@pgaudet pgaudet closed this as not planned Won't fix, can't repro, duplicate, stale Jul 2, 2024
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