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Merge stizolobate synthase activity & DOPA dioxygenase activity #28192

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sjm41 opened this issue Jun 18, 2024 · 0 comments
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Merge stizolobate synthase activity & DOPA dioxygenase activity #28192

sjm41 opened this issue Jun 18, 2024 · 0 comments

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@sjm41
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sjm41 commented Jun 18, 2024

These two terms are the same - same MetaCyc ID, and 4,5-seco-dopa is a synonym of "4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde"

id: GO:0050297
name: stizolobate synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde." [EC:1.13.11.29]
synonym: "3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing)" RELATED [EC:1.13.11.29]
xref: EC:1.13.11.29
xref: MetaCyc:RXN-8460
xref: RHEA:21220
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

id: GO:0046566
name: DOPA dioxygenase activity
namespace: molecular_function
def: "Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid." [PMID:11711071]
synonym: "dihydroxyphenylalanine dioxygenase activity" EXACT []
xref: MetaCyc:RXN-8460
is_a: GO:0051213 ! dioxygenase activity

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