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GO term ID and Label
GO:0101030 tRNA-guanine transglycosylation
The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine. PMID:24911101
Reason for deprecation Put an x in the appropriate box:
The reason for obsoletion is that this term represents a molecular function.
"Replace by" term (ID and label)
"Consider" term(s) (ID and label)
MF: GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity
Catalysis of the reaction: guanosine34 in tRNA + queuine = guanine + queuosine34 in tRNA.
BP: GO:0002099 tRNA wobble guanine modification
The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.
Are there annotations to this term?
How many EXP: 14
Are there mappings and cross references to this term? (InterPro, Keywords; check QuickGO cross-references section)
IPR004803
Is this term in a subset? (check the AmiGO page for that term)
No
Any other information
I think we need to retain one BP for this process (i.e. GO:0002099 tRNA wobble guanine modification) as the process appears to be multi-step in bacteria and archaea (but not eukaryotes.)
E.g. IPR004803 entry says: In eukaryotes, queuine is directly exchanged into tRNA while in eubacteria, a queuine precursor (preQ1) is incorporated and ultimately modified to queuine. Archaea contain a closely related enzyme [IPR004804] that catalyses a base exchange of guanine for an archaeosine precursor. This precursor is then subsequently converted to the archaeal-specific modified base archaeosine.
Please provide as much information as you can:
GO term ID and Label
GO:0101030 tRNA-guanine transglycosylation
The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine. PMID:24911101
Reason for deprecation Put an x in the appropriate box:
"Replace by" term (ID and label)
"Consider" term(s) (ID and label)
MF: GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity
Catalysis of the reaction: guanosine34 in tRNA + queuine = guanine + queuosine34 in tRNA.
BP: GO:0002099 tRNA wobble guanine modification
The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.
Are there annotations to this term?
How many EXP: 14
Are there mappings and cross references to this term? (InterPro, Keywords; check QuickGO cross-references section)
IPR004803
Is this term in a subset? (check the AmiGO page for that term)
No
Any other information
I think we need to retain one BP for this process (i.e. GO:0002099 tRNA wobble guanine modification) as the process appears to be multi-step in bacteria and archaea (but not eukaryotes.)
E.g. IPR004803 entry says: In eukaryotes, queuine is directly exchanged into tRNA while in eubacteria, a queuine precursor (preQ1) is incorporated and ultimately modified to queuine. Archaea contain a closely related enzyme [IPR004804] that catalyses a base exchange of guanine for an archaeosine precursor. This precursor is then subsequently converted to the archaeal-specific modified base archaeosine.
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