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Proposal to deal with GO:0044403 biological process involved in symbiotic interaction #27736

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pgaudet opened this issue Apr 25, 2024 · 2 comments

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@pgaudet
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pgaudet commented Apr 25, 2024

@pmasson55 proposes that we change definition of the following terms to allow annotation of host proteins:

'biological process involved in interaction with host' http:https://purl.obolibrary.org/obo/GO_0051701
'biological process involved in interaction with symbiont' http:https://purl.obolibrary.org/obo/GO_0051702
'biological process involved in symbiotic interaction' http:https://purl.obolibrary.org/obo/GO_0044403
'biological process involved in interspecies interaction between organisms' http:https://purl.obolibrary.org/obo/GO_0044419
'biological process involved in intraspecies interaction between organisms' http:https://purl.obolibrary.org/obo/GO_0051703
'regulation of biological process involved in symbiotic interaction' http:https://purl.obolibrary.org/obo/GO_0043903

& some children like:
'migration in host'
'acquisition of nutrients from host'
'adhesion of symbiont to host'
'exit from host cell'
'symbiont entry into host'
'symbiont intracellular protein transport in host'
'symbiont-mediated killing of host cell'
'translocation of molecules into host'

@pgaudet
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pgaudet commented Jun 4, 2024

Call with @genegodbold
Maybe this could be organized like this:

. interspecies interaction
.. symbiont-mediated modulation of host process
.. venom-mediated modulation of process in another organism
.. host-mediated modulation of symbiont process
.. symbiont intracellular protein transport in host {host + symbiont proteins}
.. viral translation {host + symbiont proteins}
.. migration in host {host + symbiont proteins}
.. killing of cells of another organism
... neutrophil-mediated cell killing

@pgaudet
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pgaudet commented Jul 2, 2024

Examples:
GO:0046761 viral budding from plasma membrane - check mammalian proteins annotated to this; do we want these host proteins to be annotated to this process, or only symbiont proteins?

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