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NTR: lipid transporter inhibitor activity #23772

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RLovering opened this issue Jul 25, 2022 · 1 comment
Open

NTR: lipid transporter inhibitor activity #23772

RLovering opened this issue Jul 25, 2022 · 1 comment

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@RLovering
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Please provide as much information as you can:

  • Suggested term label:
    transporter inhibitor activity

  • Definition (free text)
    Binds to and stops, prevents or reduces the activity of a transporter, any enzyme that directs the movement of lipids into, out of or within a cell, between cells or to an acceptor membrane or lipid particle.

  • **Reference, in format PMID:18992221

  • Gene product name and ID to be annotated to this term APOC1, inhibits CETP

  • Parent term(s)

  • GO:0140678 molecular function inhibitor activity

  • NTR is_a : transporter inhibitor activity

GO:0005215 transporter activity

  • NTR regulates: transporter regulator activity
    ** NTR is_a : transporter inhibitor activity

GO:0005215 transporter activity
NTR negatively regulates : transporter inhibitor activity

Plus BP negative regulation of transport parent
NTR negatively regulates : transporter inhibitor activity

  • Children terms (if applicable) Should any existing terms that should be moved underneath this new proposed term?

  • Synonyms (please specify, EXACT, BROAD, NARROW or RELATED)

  • Cross-references

  • For enzymes, please provide RHEA and/or EC numbers.

  • Can also provide MetaCyc, KEGG, Wikipedia, and other links.

  • Any other information

@ValWood
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ValWood commented Jul 26, 2022

GO:0097690
iron ion transmembrane transporter inhibitor activity

should move under this term too.
(Or if the term is 'lipid transported inhibitor as in the header, a parent term for the 2 terms created)

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