modular & open DIA search

Implementation of the ProteinMPNN redesign approach on the SickKids HPC cluster.

Engineering crysalin lattice

Biological sequence analysis for the modern age.

Code by Lasse Blaabjerg, RaSP project

Toolkit for free-energy calculation setup/analysis and biomolecular structure handling

Novel estimator for the change in stability upon point mutation in monomeric and multimeric proteins.

Improving the quality AlphaFold predicted protein complex structure by MSA optimization

Gibbs sampling for generating protein sequences

Integrative protein sequence design with evolutionary multiobjective optimization.

FlexPose, a framework for AI-based flexible modeling of protein-ligand binding pose.

Designing high temperature protein sequences via learned language processing

Rank binders by structure modeling

Pytorch implementation for ICML 2024 paper Proteus: Exploring Protein Structure Generation for Enhanced Designability and Efficiency.

MSAGPT

Spectral Framework For AI Model Evaluation

Therapeutics Commons: Artificial Intelligence Foundation for Therapeutic Science

Code for the ProteinMPNN paper

In-house inpainting pipeline (Rfdiffusion>ProteinMPNN>AF2)