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Consensus metric #3

Merged
merged 5 commits into from
Dec 10, 2020
Merged

Consensus metric #3

merged 5 commits into from
Dec 10, 2020

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huddlej
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@huddlej huddlej commented Dec 10, 2020

Add a fitness metric based on the distance of each strain's sequence from the consensus sequence of circulating strains at a given timepoint. These results were presented in a blog post summarizing the forecasting efforts from this project and Dr. Barrat-Charlaix's project.

Adds a predictor entry in the config for simulated populations, a rule to the
Snakemake workflow, and a script to calculate the consensus sequence from
strains with non-zero frequencies at a given timepoint and the corresponding
distance from the consensus for all of those same strains. These values should
get merged into the final tip attributes table such that the
"distance_from_consensus" attribute can be used to fit a model for simulated and
natural populations.
@huddlej huddlej merged commit 6edf14b into master Dec 10, 2020
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