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Issues list

Announcing cdot: a data provider to load lots of transcripts fast resurrected
#634 opened Feb 3, 2022 by davmlaw
20
FLT3 Large Insertion Generating Incorrect HGVS_P bug Something isn't working
#482 opened Feb 27, 2018 by akeeeshi
17
make data provider dependencies optional keep alive exempt issue from staleness checks
#199 opened Jul 19, 2014 by reece
13
How to apply a protein change to a given amino acid sequence to produce a mutant amino acid sequence keep alive exempt issue from staleness checks
#641 opened Jun 24, 2022 by nh13
10
In-frame del at the end of a transcript throws Index Error bug Something isn't working
#529 opened Oct 22, 2018 by sptaylor
9
Ambiguous genome-transcript alignments cause ambiguous variant projections keep alive exempt issue from staleness checks
#514 opened Aug 23, 2018 by reece
8
mitochondria (m.) assembly mapping keep alive exempt issue from staleness checks
#663 opened Jul 5, 2023 by davmlaw
7
Index Error for variant using am37.c_to_g() bug Something isn't working
#606 opened Jul 30, 2020 by sptaylor
7
support uncertain ranges enhancement New feature or request keep alive exempt issue from staleness checks
#225 opened Apr 22, 2015 by reece
7
Consider exposing a utility for converting between g. variants by leveraging pyliftover enhancement New feature or request keep alive exempt issue from staleness checks
#711 opened Nov 17, 2023 by mihaitodor
6
Inconsistencies across intron/exon boundaries keep alive exempt issue from staleness checks
#655 opened May 23, 2023 by cassiemk
1
6
Provide utility to generate transcript variants from HGVS-ish expressions with gene names keep alive exempt issue from staleness checks
#517 opened Aug 27, 2018 by reece
@reece
6
untangle lru_cache and persistent cache keep alive exempt issue from staleness checks
#450 opened Jun 26, 2017 by reece
6
Validation - refactor to be able to retrieve all errors rather than throw exception on 1st enhancement New feature or request keep alive exempt issue from staleness checks
#706 opened Oct 9, 2023 by davmlaw
5
Make data provider config explicit keep alive exempt issue from staleness checks
#645 opened Nov 12, 2022 by reece
@reece
5
Investigate replacing psycopg2 with asyncpg
#603 opened Jul 12, 2020 by reece
5
require points or ranges as appropriate for edit type keep alive exempt issue from staleness checks
#279 opened Sep 23, 2015 by reece
5
Normalizer.normalize() is performing sequence position validation which cannot be skipped keep alive exempt issue from staleness checks
#705 opened Oct 9, 2023 by mihaitodor
4
Normalizer constructor doesn't pass the validate param to the VariantMapper constructor keep alive exempt issue from staleness checks
#704 opened Oct 7, 2023 by mihaitodor
4
Exon boundary / intron validation - need for genome build specific validation? data provider schema change enhancement New feature or request keep alive exempt issue from staleness checks
#700 opened Sep 28, 2023 by davmlaw
4
Update / modernize packaging keep alive exempt issue from staleness checks
#691 opened Sep 14, 2023 by reece
4
Support for circular genomic identifiers keep alive exempt issue from staleness checks
#650 opened Apr 3, 2023 by mbiokyle29
4
Support transcript variants with specification of underlying genomic reference keep alive exempt issue from staleness checks
#642 opened Sep 30, 2022 by reece
4
move SequenceVariant.fill_ref() to separate module keep alive exempt issue from staleness checks
#593 opened Mar 25, 2020 by reece
4
RFC: Develop plan to replace Parsley keep alive exempt issue from staleness checks
#505 opened Jul 25, 2018 by reece
4
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