The source code in this repository accompanies the articles series at https://blog.f0b.org/

I recommend to start working with the PoCs in a virtual machine without any protections (Yama, SELinux, etc.) on. You can enable protections (see part 3 of the series) to see their impact.

Do note, however, that pwntools, a tool used for most Python-based PoCs, uses the Unicorn engine. This tool will not work with certain protections on, but it does not mean that the technique(s) cannot be used with those protections on.