Dataset downloaded from https://openneuro.org/datasets/ds000174/versions/1.0.1 and is in the classic BIDS format. Original paper by Koenders et. al: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152482

• 42 Patients (20 Cannabis Users, 22 Controls) each with 2 MRIs (one at a baseline time, and one at a 3-year follow-up)
• Each MRI has an assigned CUDIT score (higher CUDIT = heavier cannabis consumption) in participants.tsv
• MRI Images in mri_data folder

Environment Conditions

1. pip install nilearn
2. pip install monai
3. pip install torch
4. pip install tensorflow
5. pip install keras
6. python 3.6.1

Experiments:

• Binary Classification of MRI images as "Heavy Cannabis User" or "Control"
• CUDIT score prediction (higher CUDIT -> more cannabis use)
• Decoding Voxels of High Predictive Value

How to Run?

• in "main.py" there are several hyperparameters denoting which task to run, and how to run it. After configuring, in the command line execute: python main.py
• The "run_tests.py" file is responsible for running everything: training/validating CNNs, Decoders, etc... and is called on by main.py

"How can this be adapted to my own project?"

• Inside the 'mri_data' folder, all the subject data is there and formatted by the BIDS format. This is a consistent format accross many OpenNeuroCV datasets. In "File_Structure.py", there is code for extracting all of the MRI filenames including their 'location paths' and labelling them based on the "participants.tsv" file.
• As long as you can create an array X = all filenames including the paths to those files, and y = the labels of these filenames, they can be fed into the "evaluate" function in "run_tests".
• You may also want to adjust the self.shape attribute in run_tests to reflect the nature of your dataset.

Results:

Control vs. Heavy Cannabis Users; GridSearch at 50 Epochs

DenseNet264 at 200 Epochs

CUDIT Score

Decoding

Contact Information: Aaron: [email protected] Vivian: [email protected] Feel free to reach out!