DDxT is an automatic method for autoregressive generation of differential diagnosis (DDx) and prediction of the most likely pathology based on the patient's conditions and medical history built with Transformer.

The code is written in PyTorch. Additionally, for tokenizing and input processing, it has a dependency on the HuggingFace transformers library. All the required libraries are listed in the requirements file. Create a conda environment and install the required libraries using the following commands.

conda create -y -n ddxt
conda activate ddxt
cd $REPOSITORY_DIRECTORY
pip install -r requirements.txt

The network is trained and tested on an 8GB RTX 2070 Super Max-Q GPU with 16GB of main memory.

• PyTorch [cuda] tested on version '1.10.2'
• The working directory should have a data/ folder having all the csv datasets and json files with dataset information.
• The weights/ folder should contain a model.h5 file to successfully run the test.py file.

The working directory should have the following structure:

.
├── data/                   # contains dataset files 
├── evaluate/               # evaluation files 
├── results/                # temp cache files with eval output
├── weights/                # contains model.h5 file 
├── .gitignore
├── *.py 
└── README.md 

The code was developed for the differential diagnosis using transformers paper. For a more detailed explanation of the proposed method, please go through the pdf of the paper. If you use this work, code, or find this useful, please cite this paper as:

DDxT: Deep Generative Transformer Models for Differential Diagnosis

@article{alam2023ddxt,
  title={DDxT: Deep Generative Transformer Models for Differential Diagnosis},
  author={Alam, Mohammad Mahmudul and Raff, Edward and Oates, Tim and Matuszek, Cynthia},
  journal={arXiv preprint arXiv:2312.01242},
  year={2023}
}

dataset.py: generates data loader for training

network.py: generates proposed network architecture

train.py: train the network

test.py: runs the network over the test dataset

Here is the output of the test.py:

Loading data & network ...
Start testing ...
test ddx acc: 73.71%, test cls acc: 99.50%, eta: 2.7e+02s

inference.py: runs the inference over a single sample of the dataset

The rest of the files are utility and helper files used to do the preprocessing task.

preprocess.py: parse the dataset content

read_utils.py: read condition and evidence information of the dataset

utils.py: evaluating function utilized during training

vocab.py: generates vocabulary for both encoder and decoder