18-Deoxyaldosterone
Appearance
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Other names | 11β,18-epoxy-21-hydroxypregn-4-ene-3,20-dione, 11β-11,18-epoxy-21-hydroxypregn-4-ene-3,20-dione, 11β,18-epoxy-21-hydroxy-progesterone, 21-hydroxy-11β,18-oxido-4-pregnene-3,20-dione[1] |
Drug class | Antimineralocorticoid |
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Chemical and physical data | |
Formula | C21H28O4 |
Molar mass | 344.451 g·mol−1 |
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18-Deoxyaldosterone is a steroidal antimineralocorticoid with mixed agonist–antagonist but predominantly antagonistic activity at the mineralocorticoid receptor.[2]
References
[edit]- ^ "(11beta)-11,18-Epoxy-21-hydroxypregn-4-ene-3,20-dione".
- ^ Duax WL, Griffin JF, Strong PD, Funder JW, Ulick S (1982). "Molecular structure of 18-deoxyaldosterone and its relationship to receptor binding and activity". Journal of the American Chemical Society. 104 (25): 7291–7293. doi:10.1021/ja00389a063. ISSN 0002-7863.