senescence


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se·nes·cent

 (sĭ-nĕs′ənt)
adj.
1. Growing old; aging.
2. No longer dividing. Used of a cell.
[Latin senēscēns, senēscent-, present participle of senēscere, to grow old, inchoative of senēre, to be old, from senex, sen-, old; see sen- in Indo-European roots.]
se·nes′cence n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.senescence - the organic process of growing older and showing the effects of increasing agesenescence - the organic process of growing older and showing the effects of increasing age
ageing, aging
catabiosis - normal aging of cells
biological process, organic process - a process occurring in living organisms
2.senescence - the property characteristic of old agesenescence - the property characteristic of old age
agedness
oldness - the opposite of youngness
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.

senescence

noun
Old age:
age, agedness, elderliness, senectitude, year (used in plural).
The American Heritage® Roget's Thesaurus. Copyright © 2013, 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Translations

senescence

n (form) → Alterungsprozess m, → Seneszenz f (spec)
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

se·nes·cence

n. senescencia, senectud, proceso de envejecimiento.
English-Spanish Medical Dictionary © Farlex 2012
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References in periodicals archive ?
To achieve this, lead author Alireza Delfarah, a graduate student in the Graham lab, focused on senescence, a natural process in which cells permanently stop creating new cells.
New Cause of Cell Aging Discovered
A graduate student working under him at the Graham lab, lead author Alireza Delfarah, decided to study the process during which cells stop proliferating called senescence. When senescence occurs, it could manifest in a host of diseases such as arthritis, osteoporosis and cardiovascular trouble.A
Scientists Uncover What Keeps Cells Young
First, we force the cancer cells to age prematurely i.e., we force them into senescence. This is the first therapeutic punch.
Researchers develop 'one-two punch' to destroy cancerous ovarian cells
Cellular senescence is the permanent cell cycle arrest evoked in response to a variety of stressors (1).
Filamin B and CD13 Are Components of Senescent Secretomes That May Be Involved in Primary (Stress Induced) and Paracrine Senescence of Mesenchymal Stromal Cells
Senescence or biological aging is inevitable but health experts recommend proper diet, healthy lifestyle, and optimism to help delay aging.
Freeze: Some things that make us look older
More alarming, the presence of just a few senescent cells produced a snowball effect, triggering senescence in a larger number of previously healthy cells.
SENOLYTICS and the Promise of a Longer Life
(6,7,8,9,10,11) Our goal was to investigate the effects of anti-VEGF drugs on viability, apoptosis, proliferation, and senescence in retinal pigment epithelium (RPE) cell culture, which can serve as an in vitro model.
The Effects of Anti-Vascular Endothelial Growth Factor Drugs on Retinal Pigment Epithelial Cell Culture
Aims: The purpose of this study was to investigate the effects of glucosamine (GlcN) on hydrogen peroxide (H[sub]2O[sub]2)-induced premature senescence in human retinal pigment epithelial (RPE) cells in vitro.
Glucosamine attenuates hydrogen peroxide-induced premature senescence in human retinal pigment epithelial cells in vitro
At the same time, senescence plays an important role in the pathogenesis of chronic lung diseases including COPD and lung fibrosis as well [2].
The Function of Ophiocordyceps sinensis in Airway Epithelial Cell Senescence in a Rat COPD Model
This special issue is focused on the factors involved in ripening, senescence, and deterioration of harvested tropical and subtropical fruits and the postharvest technologies to restrict loss and ensure the maximum quality value.
Tropical and Subtropical Fruits: Postharvest Biology and Storage
The intracellular molecular mechanism of such effects is still unclear, which may involve oxidative stress [18], gene instability [16], and the regulation of p53 and p16 [18, 20, 21], but many experimental studies imply that in principle, hypoxia promotes MSC long-term expansion by slowing down replicative senescence, that is, the inherent division limitation of cultured cells even in an ideal environment [11, 12, 16, 22].
Mathematical Modeling Reveals the Role of Hypoxia in the Promotion of Human Mesenchymal Stem Cell Long-Term Expansion

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