agglutinin


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Related to agglutinin: cold agglutinin

ag·glu·ti·nin

 (ə-glo͞ot′n-ĭn)
n.
An antibody or other substance that is capable of causing agglutination, as of red blood cells or bacteria.
[agglutin(ation) + -in.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

agglutinin

(əˈɡluːtɪnɪn)
n
(Biology) a substance, such as an antibody or a lectin, that causes agglutination of cells or bacteria
[C19: agglutinate + -in]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ag•glu•ti•nin

(əˈglut n ɪn)

n.
an antibody that causes agglutination.
[1895–1900]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.agglutinin - an antibody that causes agglutination of a specific antigen
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
isoagglutinin - an antibody produced by one individual that causes agglutination of red blood cells in other individuals of the same species
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
Lectin Wheat germ agglutinin (WGA) conjugated with isitiosionate of fluoresceine (WGA-FITC) has been used to identify these carbohydrates in vitro.
Sperm Morphophysiology in Different Sections of the Rooster Reproductive Tract/Morfofisiologia Espermatica en Diferentes Secciones del Tracto Reproductivo del Gallo
Apellis is currently evaluating APL-2 in clinical studies in patients with geographic atrophy (GA), in patients with paroxysmal nocturnal hemoglobinuria (PNH) who are being treated with eculizumab or who are naive to complement inhibitor treatment, in patients with warm autoimmune hemolytic anemia (wAIHA) or cold agglutinin disease (CAD) and in patients with complement-dependent nephropathies.
Apellis Pharmaceuticals Reports Second Quarter 2019 Business Update and Financial Results
Apellis Pharmaceuticals announced updated data from its Phase 2 PLAUDIT study of APL-2 in patients with autoimmune hemolytic anemia, including cold agglutinin disease and warm antibody autoimmune hemolytic anemia.
Apellis presents data from ongoing Phase 2 PLAUDIT study of APL-2
Kumar et al that Allium cepa agglutinin increased the level of NO, TNF-a and COX-2 in CP treated immunosuppressed rats.
Amelioration of Cyclophosphamide Induced Immunosupression by the hydro-Alcoholic Extract of Gymnema Sylvestre Leaves in Albino Rats
In the case presented by the authors, IgM type autoantibodies lead to agglutination and hemolysis of erythrocytes by adhering to erythrocyte surface with complement (C3b) opsonization at low temperature (3-4 [degrees]C) in cold antibody AIHA (cold agglutinin disease) which the authors were focused on and which frequently occurs secondary to infections (1, 2, 4, 5).
Current treatment options for severe autoimmune hemolytic anemia
BioveratiVs pipeline includes a Phase III program for cold agglutinin disease, and early stage research programs and collaborations in hemophilia, and other rare blood disorders, including sickle cell disease and beta thalassemia.
Sanofi Acquires Bioverativ for $11,6B
The first case report of autoimmune hemolytic anemia in brucellosis was described due to cold agglutinin antibodies [7], but hemolysis was mild in their case which was resolved with antibiotic treatment for brucellosis.
Acute Brucellosis Presenting as an Autoimmune Hemolytic Anemia
Slices were then rinsed in PBS 3x for 5min each, 50% alcohol for 30min, and PBS 3x for 5 min each and incubated and gently rocked in 1 : 500 fluorescein-conjugated Wisteria floribunda agglutinin (WFA, Vector Laboratories, Burlingame, CA) in PBS overnight (~20 hr) at 4[degrees]C.
Consumption of a High-Fat Diet Alters Perineuronal Nets in the Prefrontal Cortex
As part of the acquisition, Bioverativ will obtain worldwide rights to True North's lead candidate, TNT009, a monoclonal antibody in development to treat cold agglutinin disease, a hemolytic condition.
Bioverativ Closes Acquisition of Rare Disease Specialist True North Therapeutics
The category of cold hemolysins includes 2 distinct disease entities: cold agglutinin syndrome and paroxysmal cold hemoglobinuria, either of which should demonstrate a DAT positive only with C3 antisera.
The Direct Antiglobulin Test: Indications, Interpretation, and Pitfalls
Serology performed to detect other infections indicated a cold agglutinin titer of 1: 320 and an M.
A Rare Case of Cavitary Lesion of the Lung Caused by Mycoplasma pneumoniae in an Immunocompetent Patient
Especially in endemic areas, the Widal test is still of significant diagnostic value, provided judicious interpretation of the test is made against a background of pertinent information, especially data which relate to agglutinin levels in normal individuals and in nontyphoidal fevers common in the region [8].
Baseline Antibody Titre against Salmonella enterica in Healthy Population of Mumbai, Maharashtra, India

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